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- W2894619130 abstract "Systemic inflammation is known to cause WBC abnormalities, specifically neutrophilia and lymphopenia. The neutrophil-to-lymphocyte ratio (NLR) is a simple and affordable biomarker that has been used in human clinical settings of sepsis but has not been investigated in veterinary species. We evaluated NLR in dogs with septic and nonseptic systemic inflammatory diseases and compared with a healthy dog population. An NLR ≥6 had an 84.39% sensitivity and 86.95% specificity to identify dogs with systemic inflammatory states; however, no ratio distinguished septic and nonseptic causes. The NLR was not associated with length of hospitalization, morbidity based on the acute patient physiologic laboratory evaluation scoring system, or mortality. The disassociation may be due to the retrospective nature of the study, including a restricted population size and acquisition of only a one-time blood sample. NLR is currently of limited use for diagnosis and prognosis in systemic inflammatory states in dogs, and larger, prospective studies are necessary to further evaluate NLR." @default.
- W2894619130 created "2018-10-12" @default.
- W2894619130 creator A5056727749 @default.
- W2894619130 creator A5056884019 @default.
- W2894619130 creator A5081505177 @default.
- W2894619130 date "2018-10-03" @default.
- W2894619130 modified "2023-09-26" @default.
- W2894619130 title "Utility and Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Dogs with Septic Peritonitis." @default.
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- W2894619130 doi "https://doi.org/10.5326/jaaha-ms-6808" @default.
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- W2894619130 hasPublicationYear "2018" @default.
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