Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894628829> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2894628829 abstract "Neuregulin (NRG)-1 is implicated in the preservation of left ventricular function in pathophysiological conditions. However, the role of NRG-1 in right ventricular (RV) failure is still unknown. We analysed the effects of NRG-1 treatment in an animal model of pulmonary arterial hypertension (PAH) and RV heart failure (HF). Male Wistar rats (180-200g) randomly received monocrotaline (MCT, 60mg/Kg,sc) or vehicle. After 14 days, animals randomly received NRG-1 (40µg/Kg/day,ip) or vehicle, resulting in 4 groups: ctrl (n=10); ctrl+NRG (n=10); MCT (n=10); MCT+NRG (n=10). RV hemodynamics and sample collection for vascular, morphometric, histologic and molecular studies were performed 25-28 days after MCT administration. Only significant results (mean±SEM, p<0.05) are given. MCT group developed PAH, as shown by increased RV maximum pressure (MCT vs ctrl: 63±3 vs 34±3mmHg) and by decreased cardiac output (MCT vs ctrl: 34±4 vs 65±4mL/min) which were both attenuated in the MCT+NRG group (53±3mmHg and 52±2mL/min). An..." @default.
- W2894628829 created "2018-10-12" @default.
- W2894628829 creator A5039151849 @default.
- W2894628829 creator A5051783080 @default.
- W2894628829 creator A5052974638 @default.
- W2894628829 creator A5054708047 @default.
- W2894628829 creator A5060298206 @default.
- W2894628829 creator A5063133041 @default.
- W2894628829 creator A5068149383 @default.
- W2894628829 creator A5070088160 @default.
- W2894628829 creator A5078540677 @default.
- W2894628829 date "2012-11-20" @default.
- W2894628829 modified "2023-10-13" @default.
- W2894628829 title "Abstract 14403: Neuregulin Attenuates Right Ventricular and Pulmonary Endothelial Dysfunction in an Experimental Model of Pulmonary Hypertension" @default.
- W2894628829 hasPublicationYear "2012" @default.
- W2894628829 type Work @default.
- W2894628829 sameAs 2894628829 @default.
- W2894628829 citedByCount "0" @default.
- W2894628829 crossrefType "journal-article" @default.
- W2894628829 hasAuthorship W2894628829A5039151849 @default.
- W2894628829 hasAuthorship W2894628829A5051783080 @default.
- W2894628829 hasAuthorship W2894628829A5052974638 @default.
- W2894628829 hasAuthorship W2894628829A5054708047 @default.
- W2894628829 hasAuthorship W2894628829A5060298206 @default.
- W2894628829 hasAuthorship W2894628829A5063133041 @default.
- W2894628829 hasAuthorship W2894628829A5068149383 @default.
- W2894628829 hasAuthorship W2894628829A5070088160 @default.
- W2894628829 hasAuthorship W2894628829A5078540677 @default.
- W2894628829 hasConcept C10162356 @default.
- W2894628829 hasConcept C126322002 @default.
- W2894628829 hasConcept C164705383 @default.
- W2894628829 hasConcept C170493617 @default.
- W2894628829 hasConcept C178853913 @default.
- W2894628829 hasConcept C26635844 @default.
- W2894628829 hasConcept C2778117688 @default.
- W2894628829 hasConcept C2778198053 @default.
- W2894628829 hasConcept C2778560701 @default.
- W2894628829 hasConcept C2780930700 @default.
- W2894628829 hasConcept C2909878918 @default.
- W2894628829 hasConcept C2993376042 @default.
- W2894628829 hasConcept C71924100 @default.
- W2894628829 hasConcept C84393581 @default.
- W2894628829 hasConceptScore W2894628829C10162356 @default.
- W2894628829 hasConceptScore W2894628829C126322002 @default.
- W2894628829 hasConceptScore W2894628829C164705383 @default.
- W2894628829 hasConceptScore W2894628829C170493617 @default.
- W2894628829 hasConceptScore W2894628829C178853913 @default.
- W2894628829 hasConceptScore W2894628829C26635844 @default.
- W2894628829 hasConceptScore W2894628829C2778117688 @default.
- W2894628829 hasConceptScore W2894628829C2778198053 @default.
- W2894628829 hasConceptScore W2894628829C2778560701 @default.
- W2894628829 hasConceptScore W2894628829C2780930700 @default.
- W2894628829 hasConceptScore W2894628829C2909878918 @default.
- W2894628829 hasConceptScore W2894628829C2993376042 @default.
- W2894628829 hasConceptScore W2894628829C71924100 @default.
- W2894628829 hasConceptScore W2894628829C84393581 @default.
- W2894628829 hasLocation W28946288291 @default.
- W2894628829 hasOpenAccess W2894628829 @default.
- W2894628829 hasPrimaryLocation W28946288291 @default.
- W2894628829 hasRelatedWork W1579954063 @default.
- W2894628829 hasRelatedWork W1586552449 @default.
- W2894628829 hasRelatedWork W1962389239 @default.
- W2894628829 hasRelatedWork W1989649500 @default.
- W2894628829 hasRelatedWork W2004360667 @default.
- W2894628829 hasRelatedWork W2009010735 @default.
- W2894628829 hasRelatedWork W2041329079 @default.
- W2894628829 hasRelatedWork W2247850667 @default.
- W2894628829 hasRelatedWork W2288611601 @default.
- W2894628829 hasRelatedWork W2292559722 @default.
- W2894628829 hasRelatedWork W2316392413 @default.
- W2894628829 hasRelatedWork W2351626409 @default.
- W2894628829 hasRelatedWork W2391314801 @default.
- W2894628829 hasRelatedWork W2393424567 @default.
- W2894628829 hasRelatedWork W2550232145 @default.
- W2894628829 hasRelatedWork W2726671021 @default.
- W2894628829 hasRelatedWork W2727603424 @default.
- W2894628829 hasRelatedWork W3028750049 @default.
- W2894628829 hasRelatedWork W3095434340 @default.
- W2894628829 hasRelatedWork W39080948 @default.
- W2894628829 isParatext "false" @default.
- W2894628829 isRetracted "false" @default.
- W2894628829 magId "2894628829" @default.
- W2894628829 workType "article" @default.