FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894630001> ?p ?o ?g. }

• W2894630001 endingPage "e88" @default.
• W2894630001 startingPage "e81" @default.
• W2894630001 abstract "In both acute graft‐versus‐host disease (GVHD) and lupus erythematosus (LE), the patient's own tissues are subjected to immunological assault via complex mechanisms influenced by interferon (IFN) and other cytokines. Although not typically confused clinically, these entities have overlapping histopathological findings in the skin. To assess whether GVHD can be differentiated from LE using molecular methods on skin specimens. We developed a quantitative reverse transcription PCR assay based on previously identified tissue‐based biomarkers of cutaneous GVHD, and compared gene expression in GVHD with that in LE. Both entities showed robust expression of IFN‐induced genes and of genes encoding proteins involved in antigen presentation, cell signalling and tissue repair. Levels of gene expression differed significantly in GVHD compared with LE, particularly those of IFN‐induced genes such as MX1, OAS3, TAP1 and STAT3 (P < 0.01). Three logistic regression models could differentiate the two entities with a high degree of certainty (receiver operating characteristic area under the curve of 1.0). The study demonstrates the feasibility of distinguishing between microscopically similar inflammatory dermatoses using tissue‐based molecular techniques." @default.
• W2894630001 created "2018-10-12" @default.
• W2894630001 creator A5020953597 @default.
• W2894630001 creator A5022328904 @default.
• W2894630001 creator A5036477761 @default.
• W2894630001 creator A5040139732 @default.
• W2894630001 creator A5042678113 @default.
• W2894630001 creator A5042915360 @default.
• W2894630001 creator A5043033429 @default.
• W2894630001 creator A5058060310 @default.
• W2894630001 creator A5063383942 @default.
• W2894630001 creator A5064721834 @default.
• W2894630001 creator A5084606047 @default.
• W2894630001 creator A5085360755 @default.
• W2894630001 date "2018-10-02" @default.
• W2894630001 modified "2023-10-18" @default.
• W2894630001 title "Differential expression of interferon‐induced genes and other tissue‐based biomarkers in acute graft‐versus‐host disease vs. lupus erythematosus in skin" @default.
• W2894630001 cites W1996518557 @default.
• W2894630001 cites W1997458644 @default.
• W2894630001 cites W2013130330 @default.
• W2894630001 cites W2015445702 @default.
• W2894630001 cites W2028385745 @default.
• W2894630001 cites W2060795000 @default.
• W2894630001 cites W2068765603 @default.
• W2894630001 cites W2087613277 @default.
• W2894630001 cites W2094901150 @default.
• W2894630001 cites W2106273198 @default.
• W2894630001 cites W2142884221 @default.
• W2894630001 cites W2152185706 @default.
• W2894630001 cites W2154243191 @default.
• W2894630001 cites W2156184478 @default.
• W2894630001 cites W2160431507 @default.
• W2894630001 cites W2163274288 @default.
• W2894630001 cites W2166338481 @default.
• W2894630001 cites W2331678896 @default.
• W2894630001 cites W2581947608 @default.
• W2894630001 cites W2626177916 @default.
• W2894630001 cites W2755469868 @default.
• W2894630001 doi "https://doi.org/10.1111/ced.13759" @default.
• W2894630001 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6445793" @default.
• W2894630001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30280423" @default.
• W2894630001 hasPublicationYear "2018" @default.
• W2894630001 type Work @default.
• W2894630001 sameAs 2894630001 @default.
• W2894630001 citedByCount "4" @default.
• W2894630001 countsByYear W28946300012022 @default.
• W2894630001 countsByYear W28946300012023 @default.
• W2894630001 crossrefType "journal-article" @default.
• W2894630001 hasAuthorship W2894630001A5020953597 @default.
• W2894630001 hasAuthorship W2894630001A5022328904 @default.
• W2894630001 hasAuthorship W2894630001A5036477761 @default.
• W2894630001 hasAuthorship W2894630001A5040139732 @default.
• W2894630001 hasAuthorship W2894630001A5042678113 @default.
• W2894630001 hasAuthorship W2894630001A5042915360 @default.
• W2894630001 hasAuthorship W2894630001A5043033429 @default.
• W2894630001 hasAuthorship W2894630001A5058060310 @default.
• W2894630001 hasAuthorship W2894630001A5063383942 @default.
• W2894630001 hasAuthorship W2894630001A5064721834 @default.
• W2894630001 hasAuthorship W2894630001A5084606047 @default.
• W2894630001 hasAuthorship W2894630001A5085360755 @default.
• W2894630001 hasBestOaLocation W28946300012 @default.
• W2894630001 hasConcept C104317684 @default.
• W2894630001 hasConcept C142724271 @default.
• W2894630001 hasConcept C150194340 @default.
• W2894630001 hasConcept C159654299 @default.
• W2894630001 hasConcept C203014093 @default.
• W2894630001 hasConcept C2775915377 @default.
• W2894630001 hasConcept C2776178377 @default.
• W2894630001 hasConcept C2779134260 @default.
• W2894630001 hasConcept C2779972918 @default.
• W2894630001 hasConcept C2780841837 @default.
• W2894630001 hasConcept C54355233 @default.
• W2894630001 hasConcept C71924100 @default.
• W2894630001 hasConcept C86803240 @default.
• W2894630001 hasConcept C8891405 @default.
• W2894630001 hasConceptScore W2894630001C104317684 @default.
• W2894630001 hasConceptScore W2894630001C142724271 @default.
• W2894630001 hasConceptScore W2894630001C150194340 @default.
• W2894630001 hasConceptScore W2894630001C159654299 @default.
• W2894630001 hasConceptScore W2894630001C203014093 @default.
• W2894630001 hasConceptScore W2894630001C2775915377 @default.
• W2894630001 hasConceptScore W2894630001C2776178377 @default.
• W2894630001 hasConceptScore W2894630001C2779134260 @default.
• W2894630001 hasConceptScore W2894630001C2779972918 @default.
• W2894630001 hasConceptScore W2894630001C2780841837 @default.
• W2894630001 hasConceptScore W2894630001C54355233 @default.
• W2894630001 hasConceptScore W2894630001C71924100 @default.
• W2894630001 hasConceptScore W2894630001C86803240 @default.
• W2894630001 hasConceptScore W2894630001C8891405 @default.
• W2894630001 hasFunder F4320332161 @default.
• W2894630001 hasIssue "4" @default.
• W2894630001 hasLocation W28946300011 @default.
• W2894630001 hasLocation W28946300012 @default.
• W2894630001 hasLocation W28946300013 @default.
• W2894630001 hasOpenAccess W2894630001 @default.
• W2894630001 hasPrimaryLocation W28946300011 @default.
• W2894630001 hasRelatedWork W2009966535 @default.
• W2894630001 hasRelatedWork W2045903301 @default.

• next