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- W2894655918 abstract "Introduction: Endoscopic biliary drainage (EBD) or percutaneous transhepatic biliary drainage (PTBD) are recommended to improve liver function before major hepatectomy for perihilar cholangiocarcinoma (PHC). However infectious drainage-related complications are associated with both methods. Aim of this study was to evaluate the operative risk associated with EBD and PTBD. Method: Retrospective multicenter study including 14 Italian hepatobiliary centers, members of the Italian Chapter of the International Hepato-Pancreato-Biliary-Association. Patients undergoing associated major hepatectomy for PHC between 2000 and 2016 were included. Results: Data were available on 639 patients. Preoperative biliary drainage was performed in 69% of patients (range 38%-93%). PTBD was used in 51% of patients. Morbidity rate after biliary drainage was 35.8% and it was not significantly different between the two methods (27.1% after PTBD and 26.7% after EBD; p=ns). Infectious complications were the most frequent cause of morbidity (64.5%). Morbidity was significantly higher in Bismuth type 1-2 than in Bismuth type 3-4 (22.6% vs. 38.6%; p=0.01). In Bismuth type 3-4, morbidity rate was not significantly different according to the type of drainage (37.3% after PTBD vs. 44.4% after EBD; p=ns). Unilateral drainage of the future remnant liver was the preferred method of drainage (78.7%) and its failure rate was 14.8%. Conclusions: Morbidity rate following biliary drainage was not correlated with the type of drainage but with the complexity of biliary stricture. Unilateral biliary drainage of the future remnant liver was associated with low risk of failure." @default.
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- W2894655918 date "2018-09-01" @default.
- W2894655918 modified "2023-09-29" @default.
- W2894655918 title "Preoperative biliary drainage in perihilar cholangiocarcinoma: results of an Italian multicenter study" @default.
- W2894655918 doi "https://doi.org/10.1016/j.hpb.2018.06.029" @default.
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