Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894754683> ?p ?o ?g. }
- W2894754683 abstract "Hepatitis B infection in pregnancy mandates careful monitoring and specialized management according to the phase of hepatitis B infection. Perinatal transmission may be prevented by antiviral therapy in mothers with high viral load and timely immunoprophylaxis of the infant.This review focuses on the current first-line therapies for treating hepatitis B in pregnancy, timing of therapy, and prevention of perinatal transmission. Strategies to manage disease at the various phases and potential emerging therapies in phase III of development are also covered. Medline/PubMed and Cochrane databases were searched systematically from 1990 to April 2018 with the relevant articles selected for the review.Universal antenatal screening for hepatitis B and strict immunoprophylaxis for infants form the cornerstones to prevent hepatitis B virus (HBV) perinatal transmission. Tenofovir is the preferred drug for treatment in pregnancy in view of its good efficacy and high barrier to resistance. Most of the data on antivirals are from cohort studies which are prone to bias and more randomized controlled trials (RCTs) are needed to establish the benefits and safety of these drugs in pregnancy. Various novel drugs are in the pipeline which may pave the way for a cure in the near future." @default.
- W2894754683 created "2018-10-12" @default.
- W2894754683 creator A5011291757 @default.
- W2894754683 creator A5061814092 @default.
- W2894754683 date "2018-10-01" @default.
- W2894754683 modified "2023-09-24" @default.
- W2894754683 title "Synthetic therapeutics for the treatment of hepatitis B during pregnancy" @default.
- W2894754683 cites W1491418174 @default.
- W2894754683 cites W1599401828 @default.
- W2894754683 cites W1599791623 @default.
- W2894754683 cites W1774753613 @default.
- W2894754683 cites W1799522345 @default.
- W2894754683 cites W1924400606 @default.
- W2894754683 cites W1971363541 @default.
- W2894754683 cites W1984642053 @default.
- W2894754683 cites W1984902032 @default.
- W2894754683 cites W1988373760 @default.
- W2894754683 cites W1990676851 @default.
- W2894754683 cites W1996748009 @default.
- W2894754683 cites W1997945587 @default.
- W2894754683 cites W1998676987 @default.
- W2894754683 cites W2002557265 @default.
- W2894754683 cites W2008007496 @default.
- W2894754683 cites W2011592321 @default.
- W2894754683 cites W2019630600 @default.
- W2894754683 cites W2020014655 @default.
- W2894754683 cites W2030377672 @default.
- W2894754683 cites W2036759602 @default.
- W2894754683 cites W2039377491 @default.
- W2894754683 cites W2041109259 @default.
- W2894754683 cites W2044262098 @default.
- W2894754683 cites W2046912745 @default.
- W2894754683 cites W2047453765 @default.
- W2894754683 cites W2054581016 @default.
- W2894754683 cites W2066518280 @default.
- W2894754683 cites W2076431271 @default.
- W2894754683 cites W2081319861 @default.
- W2894754683 cites W2097818418 @default.
- W2894754683 cites W2098793704 @default.
- W2894754683 cites W2100587137 @default.
- W2894754683 cites W2104428567 @default.
- W2894754683 cites W2104563699 @default.
- W2894754683 cites W2106427665 @default.
- W2894754683 cites W2111565637 @default.
- W2894754683 cites W2112837294 @default.
- W2894754683 cites W2119532660 @default.
- W2894754683 cites W2124106198 @default.
- W2894754683 cites W2124446453 @default.
- W2894754683 cites W2127949912 @default.
- W2894754683 cites W2132928794 @default.
- W2894754683 cites W2135058162 @default.
- W2894754683 cites W2135844355 @default.
- W2894754683 cites W2142974747 @default.
- W2894754683 cites W2147283902 @default.
- W2894754683 cites W2159888649 @default.
- W2894754683 cites W2170455693 @default.
- W2894754683 cites W2173274566 @default.
- W2894754683 cites W2261427425 @default.
- W2894754683 cites W2314901126 @default.
- W2894754683 cites W2320554553 @default.
- W2894754683 cites W2329845985 @default.
- W2894754683 cites W2333754626 @default.
- W2894754683 cites W2343275121 @default.
- W2894754683 cites W2410353220 @default.
- W2894754683 cites W2442031947 @default.
- W2894754683 cites W2553959110 @default.
- W2894754683 cites W2554497669 @default.
- W2894754683 cites W2560975765 @default.
- W2894754683 cites W2565265846 @default.
- W2894754683 cites W2605785536 @default.
- W2894754683 cites W2608041479 @default.
- W2894754683 cites W2618139062 @default.
- W2894754683 cites W2765452995 @default.
- W2894754683 cites W2766060653 @default.
- W2894754683 cites W2768358871 @default.
- W2894754683 cites W2787656523 @default.
- W2894754683 cites W2791839818 @default.
- W2894754683 cites W2793736750 @default.
- W2894754683 cites W2886008167 @default.
- W2894754683 doi "https://doi.org/10.1080/14656566.2018.1527313" @default.
- W2894754683 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30273073" @default.
- W2894754683 hasPublicationYear "2018" @default.
- W2894754683 type Work @default.
- W2894754683 sameAs 2894754683 @default.
- W2894754683 citedByCount "0" @default.
- W2894754683 crossrefType "journal-article" @default.
- W2894754683 hasAuthorship W2894754683A5011291757 @default.
- W2894754683 hasAuthorship W2894754683A5061814092 @default.
- W2894754683 hasConcept C119599485 @default.
- W2894754683 hasConcept C126322002 @default.
- W2894754683 hasConcept C127413603 @default.
- W2894754683 hasConcept C142462285 @default.
- W2894754683 hasConcept C168563851 @default.
- W2894754683 hasConcept C177713679 @default.
- W2894754683 hasConcept C203014093 @default.
- W2894754683 hasConcept C2522874641 @default.
- W2894754683 hasConcept C2776455275 @default.
- W2894754683 hasConcept C2777382497 @default.
- W2894754683 hasConcept C2779234561 @default.
- W2894754683 hasConcept C2780593183 @default.