Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894810794> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2894810794 abstract "Background: Communication deficits are common and disabling after both left hemisphere (LH) and right hemisphere (RH) stroke, and can be quantified by the number of Content Units (CU; concepts mentioned by healthy speakers) in describing the cookie theft picture from the NIHSS. In LH and RH stroke, CU correlates with lesion volume. Hypothesis: Communication recovery in LH and RH stroke is influenced by % damage to specific areas or vascular territories, independently of lesion volume and initial severity. Methods: 25 acute ischemic RH (n=9) and LH (n=16) stroke patients were evaluated with DWI and described the NIHSS picture <24 from onset and again at 6 months. Communication recovery was measured by change in CU divided by baseline CU. A radiologist identified % damage to each cortical lobe, thalamus, basal ganglia, and each vascular territory on DWI, after co-registration to an atlas. We identified variables (age, infarct volume, initial CU, % damage to each region and vascular territory) associated with achieving the highest quartile of recovery (“best recovery”) using logistic regression. Results: Together, age, lesion volume, initial CU, and % damage to each cortical/subcortical area were strongly associated with best recovery (F(9, 15) = 12.55; p< 0.00001; r 2 = 0.88), but only initial severity (CU; t=-4.95; p<0.001) and % damage to basal ganglia (BG) (t=4.77; p<0.0001) independently predicted best recovery after adjustment for other variables. Likewise, age, lesion volume, initial CU, and % damage to each vascular territory were strongly associated with best recovery (F(10, 14) = 10.13; p = 0.0001; r 2 = 0.88), but only initial CU (t=-4.56; p<0.00001) and % damage to lenticulostriate territory (t=6.44; p<0.00001) independently predicted best recovery. To explore why higher % damage to BG predicted best recovery, we examined Day 1 PWI scans. Patients with BG strokes who showed best recovery had >50% damage to BG and had cortical hypoperfusion at Day 1. We speculate that good recovery was due to cortical reperfusion, but repeat PWI scans were not obtained. Conclusions: Patients who had the most room to improve on our measure of communication showed the most recovery. Independently of initial severity, more damage to left or right BG was associated with best recovery." @default.
- W2894810794 created "2018-10-12" @default.
- W2894810794 creator A5005636192 @default.
- W2894810794 creator A5042496782 @default.
- W2894810794 creator A5046021654 @default.
- W2894810794 creator A5061316720 @default.
- W2894810794 creator A5080933856 @default.
- W2894810794 date "2018-01-22" @default.
- W2894810794 modified "2023-09-26" @default.
- W2894810794 title "Abstract WP144: Variables Associated With Recovery of Communication After Stroke" @default.
- W2894810794 doi "https://doi.org/10.1161/str.49.suppl_1.wp144" @default.
- W2894810794 hasPublicationYear "2018" @default.
- W2894810794 type Work @default.
- W2894810794 sameAs 2894810794 @default.
- W2894810794 citedByCount "0" @default.
- W2894810794 crossrefType "journal-article" @default.
- W2894810794 hasAuthorship W2894810794A5005636192 @default.
- W2894810794 hasAuthorship W2894810794A5042496782 @default.
- W2894810794 hasAuthorship W2894810794A5046021654 @default.
- W2894810794 hasAuthorship W2894810794A5061316720 @default.
- W2894810794 hasAuthorship W2894810794A5080933856 @default.
- W2894810794 hasConcept C126322002 @default.
- W2894810794 hasConcept C126838900 @default.
- W2894810794 hasConcept C127413603 @default.
- W2894810794 hasConcept C141071460 @default.
- W2894810794 hasConcept C143409427 @default.
- W2894810794 hasConcept C164705383 @default.
- W2894810794 hasConcept C1862650 @default.
- W2894810794 hasConcept C2776361831 @default.
- W2894810794 hasConcept C2778024521 @default.
- W2894810794 hasConcept C2778187257 @default.
- W2894810794 hasConcept C2778818304 @default.
- W2894810794 hasConcept C2779246727 @default.
- W2894810794 hasConcept C2779306644 @default.
- W2894810794 hasConcept C2780645631 @default.
- W2894810794 hasConcept C2781156865 @default.
- W2894810794 hasConcept C2781192897 @default.
- W2894810794 hasConcept C44249647 @default.
- W2894810794 hasConcept C529278444 @default.
- W2894810794 hasConcept C68443243 @default.
- W2894810794 hasConcept C71924100 @default.
- W2894810794 hasConcept C78519656 @default.
- W2894810794 hasConceptScore W2894810794C126322002 @default.
- W2894810794 hasConceptScore W2894810794C126838900 @default.
- W2894810794 hasConceptScore W2894810794C127413603 @default.
- W2894810794 hasConceptScore W2894810794C141071460 @default.
- W2894810794 hasConceptScore W2894810794C143409427 @default.
- W2894810794 hasConceptScore W2894810794C164705383 @default.
- W2894810794 hasConceptScore W2894810794C1862650 @default.
- W2894810794 hasConceptScore W2894810794C2776361831 @default.
- W2894810794 hasConceptScore W2894810794C2778024521 @default.
- W2894810794 hasConceptScore W2894810794C2778187257 @default.
- W2894810794 hasConceptScore W2894810794C2778818304 @default.
- W2894810794 hasConceptScore W2894810794C2779246727 @default.
- W2894810794 hasConceptScore W2894810794C2779306644 @default.
- W2894810794 hasConceptScore W2894810794C2780645631 @default.
- W2894810794 hasConceptScore W2894810794C2781156865 @default.
- W2894810794 hasConceptScore W2894810794C2781192897 @default.
- W2894810794 hasConceptScore W2894810794C44249647 @default.
- W2894810794 hasConceptScore W2894810794C529278444 @default.
- W2894810794 hasConceptScore W2894810794C68443243 @default.
- W2894810794 hasConceptScore W2894810794C71924100 @default.
- W2894810794 hasConceptScore W2894810794C78519656 @default.
- W2894810794 hasIssue "Suppl_1" @default.
- W2894810794 hasLocation W28948107941 @default.
- W2894810794 hasOpenAccess W2894810794 @default.
- W2894810794 hasPrimaryLocation W28948107941 @default.
- W2894810794 hasRelatedWork W2023600537 @default.
- W2894810794 hasRelatedWork W2053126602 @default.
- W2894810794 hasRelatedWork W2078136539 @default.
- W2894810794 hasRelatedWork W2410138994 @default.
- W2894810794 hasRelatedWork W2467439931 @default.
- W2894810794 hasRelatedWork W2594494682 @default.
- W2894810794 hasRelatedWork W4241681661 @default.
- W2894810794 hasRelatedWork W4251751770 @default.
- W2894810794 hasRelatedWork W47940077 @default.
- W2894810794 hasRelatedWork W92743545 @default.
- W2894810794 hasVolume "49" @default.
- W2894810794 isParatext "false" @default.
- W2894810794 isRetracted "false" @default.
- W2894810794 magId "2894810794" @default.
- W2894810794 workType "article" @default.