Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894828340> ?p ?o ?g. }
- W2894828340 abstract "The growth and development of follicles are a very complex physiological process that is regulated by endocrine, autocrine and paracrine mechanisms. The effect of small molecules in follicular microenvironment on follicular growth and development has not been clearly analyzed. In the present study, the metabolic changes in ovaries of FSH-stimulated mice were investigated. Metabolomic profiling of ovary stimulated by FSH were analyzed by ultra-performance liquid chromatography/mass spectrometry and characterized by principal components analysis and orthogonal partial least squares discriminant analysis. Multivariate statistical analysis identified 21 differentially metabolites in positive ion mode and 12 in negative ion mode in the FSH-treated mice compared with the control mice. These results indicated that various types of phosphatidylcholine were changed. Furthermore, the levels of L-Glutamyl 5-phosphate, N-Acetyl-L-aspartic acid, 4-fumarylacetoacetic acid, adenylylselenate and 5′-Methylthioadenosine in the ovaries of the FSH-stimulated mice were decreased. However, the levels of 19-hydroxytestosterone and 5,10-methenyltetrahydrofolic acid were significantly increased in the positive ion mode and negative ion mode, respectively. Thirty-three differential metabolites including fatty acid metabolism, amino acid metabolism and lipid metabolism in the ovaries of mice were affected by FSH injection. The findings of our study provide a new insight into understanding the follicular development." @default.
- W2894828340 created "2018-10-12" @default.
- W2894828340 creator A5006583743 @default.
- W2894828340 creator A5019218337 @default.
- W2894828340 creator A5024846006 @default.
- W2894828340 creator A5053837458 @default.
- W2894828340 creator A5062181804 @default.
- W2894828340 creator A5070935951 @default.
- W2894828340 creator A5071074966 @default.
- W2894828340 creator A5083617974 @default.
- W2894828340 date "2018-11-21" @default.
- W2894828340 modified "2023-09-27" @default.
- W2894828340 title "Metabolomic profiling of ovary in mice treated with FSH using ultra performance liquid chromatography/mass spectrometry" @default.
- W2894828340 cites W1508973695 @default.
- W2894828340 cites W1534163224 @default.
- W2894828340 cites W1575199686 @default.
- W2894828340 cites W1962029512 @default.
- W2894828340 cites W1965837061 @default.
- W2894828340 cites W1967090815 @default.
- W2894828340 cites W1970118949 @default.
- W2894828340 cites W1976997610 @default.
- W2894828340 cites W1977029333 @default.
- W2894828340 cites W1977041255 @default.
- W2894828340 cites W1978320016 @default.
- W2894828340 cites W2003749800 @default.
- W2894828340 cites W2005111721 @default.
- W2894828340 cites W2018101989 @default.
- W2894828340 cites W2020192585 @default.
- W2894828340 cites W2030619112 @default.
- W2894828340 cites W2031168019 @default.
- W2894828340 cites W2038766067 @default.
- W2894828340 cites W2045997821 @default.
- W2894828340 cites W2047501280 @default.
- W2894828340 cites W2048646391 @default.
- W2894828340 cites W2049922617 @default.
- W2894828340 cites W2059027130 @default.
- W2894828340 cites W2093650264 @default.
- W2894828340 cites W2104729475 @default.
- W2894828340 cites W2108264311 @default.
- W2894828340 cites W2109930128 @default.
- W2894828340 cites W2110267211 @default.
- W2894828340 cites W2111051013 @default.
- W2894828340 cites W2121238860 @default.
- W2894828340 cites W2130462088 @default.
- W2894828340 cites W2141354142 @default.
- W2894828340 cites W2147793398 @default.
- W2894828340 cites W2156275180 @default.
- W2894828340 cites W2156720792 @default.
- W2894828340 cites W2253477758 @default.
- W2894828340 cites W2415430559 @default.
- W2894828340 cites W2522140141 @default.
- W2894828340 cites W259746414 @default.
- W2894828340 cites W2600465435 @default.
- W2894828340 cites W2757072723 @default.
- W2894828340 doi "https://doi.org/10.1042/bsr20180965" @default.
- W2894828340 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6246768" @default.
- W2894828340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30287502" @default.
- W2894828340 hasPublicationYear "2018" @default.
- W2894828340 type Work @default.
- W2894828340 sameAs 2894828340 @default.
- W2894828340 citedByCount "4" @default.
- W2894828340 countsByYear W28948283402020 @default.
- W2894828340 countsByYear W28948283402022 @default.
- W2894828340 crossrefType "journal-article" @default.
- W2894828340 hasAuthorship W2894828340A5006583743 @default.
- W2894828340 hasAuthorship W2894828340A5019218337 @default.
- W2894828340 hasAuthorship W2894828340A5024846006 @default.
- W2894828340 hasAuthorship W2894828340A5053837458 @default.
- W2894828340 hasAuthorship W2894828340A5062181804 @default.
- W2894828340 hasAuthorship W2894828340A5070935951 @default.
- W2894828340 hasAuthorship W2894828340A5071074966 @default.
- W2894828340 hasAuthorship W2894828340A5083617974 @default.
- W2894828340 hasBestOaLocation W28948283401 @default.
- W2894828340 hasConcept C126322002 @default.
- W2894828340 hasConcept C134018914 @default.
- W2894828340 hasConcept C162356407 @default.
- W2894828340 hasConcept C185592680 @default.
- W2894828340 hasConcept C187785154 @default.
- W2894828340 hasConcept C21565614 @default.
- W2894828340 hasConcept C2776991927 @default.
- W2894828340 hasConcept C2778324911 @default.
- W2894828340 hasConcept C2778575703 @default.
- W2894828340 hasConcept C2779279165 @default.
- W2894828340 hasConcept C43617362 @default.
- W2894828340 hasConcept C4733338 @default.
- W2894828340 hasConcept C55493867 @default.
- W2894828340 hasConcept C62231903 @default.
- W2894828340 hasConcept C64489805 @default.
- W2894828340 hasConcept C71315377 @default.
- W2894828340 hasConcept C71924100 @default.
- W2894828340 hasConcept C86803240 @default.
- W2894828340 hasConceptScore W2894828340C126322002 @default.
- W2894828340 hasConceptScore W2894828340C134018914 @default.
- W2894828340 hasConceptScore W2894828340C162356407 @default.
- W2894828340 hasConceptScore W2894828340C185592680 @default.
- W2894828340 hasConceptScore W2894828340C187785154 @default.
- W2894828340 hasConceptScore W2894828340C21565614 @default.
- W2894828340 hasConceptScore W2894828340C2776991927 @default.
- W2894828340 hasConceptScore W2894828340C2778324911 @default.
- W2894828340 hasConceptScore W2894828340C2778575703 @default.