FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894848202> ?p ?o ?g. }

• W2894848202 endingPage "1465" @default.
• W2894848202 startingPage "1449" @default.
• W2894848202 abstract "The bipartite begomoviruses (Geminiviridae family), which are DNA viruses that replicate in the nucleus of infected cells, encode the nuclear shuttle protein (NSP) to facilitate the translocation of viral DNA from the nucleus to the cytoplasm via nuclear pores. This intracellular trafficking of NSP–DNA complexes is accessorized by the NSP-interacting guanosine triphosphatase (NIG) at the cytosolic side. Here, we report the nuclear redistribution of NIG by AtWWP1, a WW domain-containing protein that forms immune nuclear bodies (NBs) against begomoviruses. We demonstrated that AtWWP1 relocates NIG from the cytoplasm to the nucleus where it is confined to AtWWP1-NBs, suggesting that the NIG-AtWWP1 interaction may interfere with the NIG pro-viral function associated with its cytosolic localization. Consistent with this assumption, loss of AtWWP1 function cuased plants more susceptible to begomovirus infection, whereas overexpression of AtWWP1 enhanced plant resistance to begomovirus. Furthermore, we found that a mutant version of AtWWP1 defective for NB formation was no longer capable of interacting with and relocating NIG to the nucleus and lost its immune function against begomovirus. The antiviral function of AtWWP1-NBs, however, could be antagonized by viral infection that induced either the disruption or a decrease in the number of AtWWP1-NBs. Collectively, these results led us to propose that AtWWP1 organizes nuclear structures into nuclear foci, which provide intrinsic immunity against begomovirus infection." @default.
• W2894848202 created "2018-10-12" @default.
• W2894848202 creator A5003016098 @default.
• W2894848202 creator A5011585820 @default.
• W2894848202 creator A5019479099 @default.
• W2894848202 creator A5022403185 @default.
• W2894848202 creator A5036936758 @default.
• W2894848202 creator A5040989370 @default.
• W2894848202 creator A5042314217 @default.
• W2894848202 creator A5050367915 @default.
• W2894848202 creator A5052641740 @default.
• W2894848202 creator A5053543995 @default.
• W2894848202 creator A5056346064 @default.
• W2894848202 creator A5056585171 @default.
• W2894848202 creator A5059825221 @default.
• W2894848202 creator A5077022038 @default.
• W2894848202 creator A5087639404 @default.
• W2894848202 date "2018-12-01" @default.
• W2894848202 modified "2023-09-27" @default.
• W2894848202 title "A WW Domain-Containing Protein Forms Immune Nuclear Bodies against Begomoviruses" @default.
• W2894848202 cites W1256550256 @default.
• W2894848202 cites W1504179404 @default.
• W2894848202 cites W176028781 @default.
• W2894848202 cites W1937173755 @default.
• W2894848202 cites W1964991608 @default.
• W2894848202 cites W1969521521 @default.
• W2894848202 cites W1976387692 @default.
• W2894848202 cites W1984056794 @default.
• W2894848202 cites W1985118118 @default.
• W2894848202 cites W1986554921 @default.
• W2894848202 cites W1987129476 @default.
• W2894848202 cites W1990728090 @default.
• W2894848202 cites W2007601085 @default.
• W2894848202 cites W2013411453 @default.
• W2894848202 cites W2028031991 @default.
• W2894848202 cites W2028343167 @default.
• W2894848202 cites W2040501427 @default.
• W2894848202 cites W2043186621 @default.
• W2894848202 cites W2043189073 @default.
• W2894848202 cites W2046376048 @default.
• W2894848202 cites W2057661436 @default.
• W2894848202 cites W2059030143 @default.
• W2894848202 cites W2064432179 @default.
• W2894848202 cites W2068132079 @default.
• W2894848202 cites W2073114238 @default.
• W2894848202 cites W2077469182 @default.
• W2894848202 cites W2082720258 @default.
• W2894848202 cites W2093931964 @default.
• W2894848202 cites W2094144098 @default.
• W2894848202 cites W2100177335 @default.
• W2894848202 cites W2101314370 @default.
• W2894848202 cites W2101629560 @default.
• W2894848202 cites W2103434107 @default.
• W2894848202 cites W2105639297 @default.
• W2894848202 cites W2105677208 @default.
• W2894848202 cites W2108158374 @default.
• W2894848202 cites W2119054256 @default.
• W2894848202 cites W2119451435 @default.
• W2894848202 cites W2129798482 @default.
• W2894848202 cites W2132178599 @default.
• W2894848202 cites W2135903629 @default.
• W2894848202 cites W2137453267 @default.
• W2894848202 cites W2141466624 @default.
• W2894848202 cites W2146260171 @default.
• W2894848202 cites W2151885957 @default.
• W2894848202 cites W2157236728 @default.
• W2894848202 cites W2171305498 @default.
• W2894848202 cites W2329354687 @default.
• W2894848202 cites W2372902066 @default.
• W2894848202 cites W2408730319 @default.
• W2894848202 cites W2416119739 @default.
• W2894848202 cites W2425315149 @default.
• W2894848202 cites W2537945846 @default.
• W2894848202 cites W2588030737 @default.
• W2894848202 cites W2783538580 @default.
• W2894848202 doi "https://doi.org/10.1016/j.molp.2018.09.009" @default.
• W2894848202 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30296599" @default.
• W2894848202 hasPublicationYear "2018" @default.
• W2894848202 type Work @default.
• W2894848202 sameAs 2894848202 @default.
• W2894848202 citedByCount "10" @default.
• W2894848202 countsByYear W28948482022018 @default.
• W2894848202 countsByYear W28948482022019 @default.
• W2894848202 countsByYear W28948482022020 @default.
• W2894848202 countsByYear W28948482022021 @default.
• W2894848202 countsByYear W28948482022022 @default.
• W2894848202 countsByYear W28948482022023 @default.
• W2894848202 crossrefType "journal-article" @default.
• W2894848202 hasAuthorship W2894848202A5003016098 @default.
• W2894848202 hasAuthorship W2894848202A5011585820 @default.
• W2894848202 hasAuthorship W2894848202A5019479099 @default.
• W2894848202 hasAuthorship W2894848202A5022403185 @default.
• W2894848202 hasAuthorship W2894848202A5036936758 @default.
• W2894848202 hasAuthorship W2894848202A5040989370 @default.
• W2894848202 hasAuthorship W2894848202A5042314217 @default.
• W2894848202 hasAuthorship W2894848202A5050367915 @default.
• W2894848202 hasAuthorship W2894848202A5052641740 @default.
• W2894848202 hasAuthorship W2894848202A5053543995 @default.

• next