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- W2894877140 endingPage "2547" @default.
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- W2894877140 abstract "Didymin (isosakuranetin 7-O-rutinoside) is an orally bioactive dietary flavonoid glycoside first found in citrus fruits. Traditionally, this flavonoid has long been used in Asian countries as a dietary antioxidant. Recent studies have provided newer insights into this pleiotropic compound, which could regulate multiple biological activities of many important signaling molecules in health and disease. Emerging data also presented the potential therapeutic application of dietary flavonoid glycoside didymin against cancer, neurological diseases, liver diseases, cardiovascular diseases, and other diseases. In this review, we briefly introduce the source and extraction methods of didymin, and summarize its potential therapeutic application in the treatment of various diseases, with an emphasis on molecular targets and mechanism that contributes to the observed therapeutic effects. The dietary flavonoid didymin can be used to affect health and disease with multiple therapeutic targets, and it is anticipated that this review will stimulate the future development of this potential dietary medicine." @default.
- W2894877140 created "2018-10-12" @default.
- W2894877140 creator A5002854293 @default.
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- W2894877140 creator A5009368703 @default.
- W2894877140 creator A5045648276 @default.
- W2894877140 creator A5062500316 @default.
- W2894877140 date "2018-10-06" @default.
- W2894877140 modified "2023-10-14" @default.
- W2894877140 title "Recent Trends in Potential Therapeutic Applications of the Dietary Flavonoid Didymin" @default.
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- W2894877140 doi "https://doi.org/10.3390/molecules23102547" @default.
- W2894877140 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6222367" @default.
- W2894877140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30301216" @default.
- W2894877140 hasPublicationYear "2018" @default.
- W2894877140 type Work @default.