FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894895332> ?p ?o ?g. }

• W2894895332 abstract "Use of inhaled corticosteroids (ICS) increases the risk of pneumonia in chronic obstructive pulmonary disease (COPD), but the magnitude of risk with different ICS remains unclear. A post hoc analysis of the 4-year UPLIFT® trial to assess whether pneumonia risk differed by type of ICS (fluticasone propionate [FP], other ICS, or no ICS) in permanent users (defined by use until end of study) or in users at baseline (sensitivity analysis). For the permanent-users analysis, 825 patients receiving FP throughout the trial, 825 patients receiving other ICS and 825 patients not receiving ICS were matched on relevant baseline features 1:1:1. A significantly greater risk of pneumonia was observed for FP versus no ICS: the hazard ratio (HR) for risk of pneumonia was 1.33 (95% confidence interval [CI] 1.00, 1.75; p = 0.046) and the rate ratio (RR) was 1.58 (95% CI 1.05, 2.37; p = 0.028). A greater risk was also found for FP versus other ICS: HR 1.28 (95% CI 0.97, 1.68; p = 0.078) and RR 1.48 (95% CI 1.00, 2.19; p = 0.049). A higher proportion of patients on FP were hospitalized with pneumonia (7.9%) versus other ICS (6.7%) or no ICS (5.9%). Whilst other ICS use was associated with the highest number of fatal pneumonia events, the total number of fatal pneumonia incidents was low. A similar pattern was observed in the sensitivity analyses, which included 4002 patients on different treatments at baseline (FP, other ICS, and no ICS) and considered potential switches during the study. The results support existing evidence of an increased pneumonia risk with FP use compared with other ICS and no ICS use in patients with COPD. Healthcare professionals should evaluate the risk–benefit ratio of using ICS when making treatment decisions with their patients. Post hoc analysis of UPLIFT®. ClinicalTrials.gov number: NCT00144339 . Retrospectively registered September 2, 2005." @default.
• W2894895332 created "2018-10-12" @default.
• W2894895332 creator A5008555938 @default.
• W2894895332 creator A5019484229 @default.
• W2894895332 creator A5038228413 @default.
• W2894895332 creator A5052712328 @default.
• W2894895332 creator A5062711392 @default.
• W2894895332 creator A5071831143 @default.
• W2894895332 creator A5090100096 @default.
• W2894895332 date "2018-10-05" @default.
• W2894895332 modified "2023-10-15" @default.
• W2894895332 title "Concomitant inhaled corticosteroid use and the risk of pneumonia in COPD: a matched-subgroup post hoc analysis of the UPLIFT® trial" @default.
• W2894895332 cites W1877054624 @default.
• W2894895332 cites W1965397792 @default.
• W2894895332 cites W1987555297 @default.
• W2894895332 cites W2001104945 @default.
• W2894895332 cites W2019271924 @default.
• W2894895332 cites W2019720524 @default.
• W2894895332 cites W2032080378 @default.
• W2894895332 cites W2038568752 @default.
• W2894895332 cites W2044458860 @default.
• W2894895332 cites W2045616259 @default.
• W2894895332 cites W2047030375 @default.
• W2894895332 cites W2054517043 @default.
• W2894895332 cites W2072338852 @default.
• W2894895332 cites W2073867181 @default.
• W2894895332 cites W2077672954 @default.
• W2894895332 cites W2088889277 @default.
• W2894895332 cites W2099683633 @default.
• W2894895332 cites W2100738224 @default.
• W2894895332 cites W2117978928 @default.
• W2894895332 cites W2127104182 @default.
• W2894895332 cites W2133119676 @default.
• W2894895332 cites W2133986277 @default.
• W2894895332 cites W2134492231 @default.
• W2894895332 cites W2139192099 @default.
• W2894895332 cites W2140001959 @default.
• W2894895332 cites W2140678268 @default.
• W2894895332 cites W2141034778 @default.
• W2894895332 cites W2142724633 @default.
• W2894895332 cites W2148644252 @default.
• W2894895332 cites W2150978030 @default.
• W2894895332 cites W2155440753 @default.
• W2894895332 cites W2169401204 @default.
• W2894895332 cites W2330533577 @default.
• W2894895332 cites W2344148139 @default.
• W2894895332 cites W2512624858 @default.
• W2894895332 cites W2583265473 @default.
• W2894895332 cites W2593627766 @default.
• W2894895332 cites W2604577460 @default.
• W2894895332 cites W2766594601 @default.
• W2894895332 cites W2768238389 @default.
• W2894895332 cites W2771765861 @default.
• W2894895332 doi "https://doi.org/10.1186/s12931-018-0874-0" @default.
• W2894895332 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6173940" @default.
• W2894895332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30290801" @default.
• W2894895332 hasPublicationYear "2018" @default.
• W2894895332 type Work @default.
• W2894895332 sameAs 2894895332 @default.
• W2894895332 citedByCount "16" @default.
• W2894895332 countsByYear W28948953322019 @default.
• W2894895332 countsByYear W28948953322020 @default.
• W2894895332 countsByYear W28948953322021 @default.
• W2894895332 countsByYear W28948953322022 @default.
• W2894895332 countsByYear W28948953322023 @default.
• W2894895332 crossrefType "journal-article" @default.
• W2894895332 hasAuthorship W2894895332A5008555938 @default.
• W2894895332 hasAuthorship W2894895332A5019484229 @default.
• W2894895332 hasAuthorship W2894895332A5038228413 @default.
• W2894895332 hasAuthorship W2894895332A5052712328 @default.
• W2894895332 hasAuthorship W2894895332A5062711392 @default.
• W2894895332 hasAuthorship W2894895332A5071831143 @default.
• W2894895332 hasAuthorship W2894895332A5090100096 @default.
• W2894895332 hasBestOaLocation W28948953321 @default.
• W2894895332 hasConcept C126322002 @default.
• W2894895332 hasConcept C187960798 @default.
• W2894895332 hasConcept C207103383 @default.
• W2894895332 hasConcept C2776780178 @default.
• W2894895332 hasConcept C2776804153 @default.
• W2894895332 hasConcept C2777914695 @default.
• W2894895332 hasConcept C2779028295 @default.
• W2894895332 hasConcept C44249647 @default.
• W2894895332 hasConcept C67761136 @default.
• W2894895332 hasConcept C71924100 @default.
• W2894895332 hasConcept C82789193 @default.
• W2894895332 hasConcept C90924648 @default.
• W2894895332 hasConceptScore W2894895332C126322002 @default.
• W2894895332 hasConceptScore W2894895332C187960798 @default.
• W2894895332 hasConceptScore W2894895332C207103383 @default.
• W2894895332 hasConceptScore W2894895332C2776780178 @default.
• W2894895332 hasConceptScore W2894895332C2776804153 @default.
• W2894895332 hasConceptScore W2894895332C2777914695 @default.
• W2894895332 hasConceptScore W2894895332C2779028295 @default.
• W2894895332 hasConceptScore W2894895332C44249647 @default.
• W2894895332 hasConceptScore W2894895332C67761136 @default.
• W2894895332 hasConceptScore W2894895332C71924100 @default.
• W2894895332 hasConceptScore W2894895332C82789193 @default.
• W2894895332 hasConceptScore W2894895332C90924648 @default.
• W2894895332 hasIssue "1" @default.
• W2894895332 hasLocation W28948953321 @default.

• next