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- W2894896110 abstract "Context.— Hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC) is an uncommon disorder with germline-inactivating mutations in the fumarate hydratase (FH) gene. The kidney cancers that develop in patients with HLRCC are often unilateral and solitary, with a potentially aggressive clinical course; morphologic identification of suspicious cases is of the utmost importance. Objective.— To review classic morphologic features of HLRCC-associated renal cell carcinoma, the reported morphologic spectrum of these tumors and their mimics, and the evidence for use of immunohistochemistry and molecular testing in diagnosis of these tumors. Data Sources.— University of Michigan cases and review of pertinent literature about HLRCC and the morphologic spectrum of HLRCC-associated renal cell carcinoma. Conclusions.— Histologic features, such as prominent nucleoli with perinucleolar halos and multiple architectural patterns within one tumor, are suggestive of HLRCC-associated renal cell carcinoma. However, the morphologic spectrum is broad. Appropriate use of FH immunohistochemistry and referral to genetic counseling is important for detection of this syndrome." @default.
- W2894896110 created "2018-10-12" @default.
- W2894896110 creator A5047988040 @default.
- W2894896110 creator A5060849370 @default.
- W2894896110 creator A5089805603 @default.
- W2894896110 date "2018-10-01" @default.
- W2894896110 modified "2023-10-12" @default.
- W2894896110 title "Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome (HLRCC): A Contemporary Review and Practical Discussion of the Differential Diagnosis for HLRCC-Associated Renal Cell Carcinoma" @default.
- W2894896110 cites W1964116613 @default.
- W2894896110 cites W1967291345 @default.
- W2894896110 cites W1970421659 @default.
- W2894896110 cites W1972747987 @default.
- W2894896110 cites W1976949137 @default.
- W2894896110 cites W1982568580 @default.
- W2894896110 cites W1985132407 @default.
- W2894896110 cites W1985522572 @default.
- W2894896110 cites W1991408439 @default.
- W2894896110 cites W1994414101 @default.
- W2894896110 cites W1994419353 @default.
- W2894896110 cites W1997098864 @default.
- W2894896110 cites W1998596376 @default.
- W2894896110 cites W2002015567 @default.
- W2894896110 cites W2004056464 @default.
- W2894896110 cites W2005293813 @default.
- W2894896110 cites W2008279952 @default.
- W2894896110 cites W2013321025 @default.
- W2894896110 cites W2016972161 @default.
- W2894896110 cites W2019655769 @default.
- W2894896110 cites W2022168777 @default.
- W2894896110 cites W2023754146 @default.
- W2894896110 cites W2053928554 @default.
- W2894896110 cites W2059747280 @default.
- W2894896110 cites W2062570696 @default.
- W2894896110 cites W2065664525 @default.
- W2894896110 cites W2068892354 @default.
- W2894896110 cites W2070640824 @default.
- W2894896110 cites W2072997207 @default.
- W2894896110 cites W2078704667 @default.
- W2894896110 cites W2080212907 @default.
- W2894896110 cites W2082420723 @default.
- W2894896110 cites W2087415995 @default.
- W2894896110 cites W2089554929 @default.
- W2894896110 cites W2091941055 @default.
- W2894896110 cites W2106886066 @default.
- W2894896110 cites W2108479829 @default.
- W2894896110 cites W2110251906 @default.
- W2894896110 cites W2110394707 @default.
- W2894896110 cites W2121296807 @default.
- W2894896110 cites W2125955965 @default.
- W2894896110 cites W2129660563 @default.
- W2894896110 cites W2131964237 @default.
- W2894896110 cites W2136749294 @default.
- W2894896110 cites W2143929280 @default.
- W2894896110 cites W2144390074 @default.
- W2894896110 cites W2144502965 @default.
- W2894896110 cites W2147712199 @default.
- W2894896110 cites W2153883646 @default.
- W2894896110 cites W2155316695 @default.
- W2894896110 cites W2157817512 @default.
- W2894896110 cites W2164311435 @default.
- W2894896110 cites W2167675084 @default.
- W2894896110 cites W2169516568 @default.
- W2894896110 cites W2178443118 @default.
- W2894896110 cites W2282366831 @default.
- W2894896110 cites W2288944226 @default.
- W2894896110 cites W2294648023 @default.
- W2894896110 cites W2297190827 @default.
- W2894896110 cites W2313855800 @default.
- W2894896110 cites W2331885701 @default.
- W2894896110 cites W2342089985 @default.
- W2894896110 cites W2400586155 @default.
- W2894896110 cites W245624368 @default.
- W2894896110 cites W2515985642 @default.
- W2894896110 cites W2519800643 @default.
- W2894896110 cites W2527365254 @default.
- W2894896110 cites W2529393194 @default.
- W2894896110 cites W2560290289 @default.
- W2894896110 cites W2562768756 @default.
- W2894896110 cites W2586119740 @default.
- W2894896110 cites W2592572314 @default.
- W2894896110 cites W2597953270 @default.
- W2894896110 cites W2609187871 @default.
- W2894896110 cites W2739142491 @default.
- W2894896110 cites W2747673880 @default.
- W2894896110 cites W2766175335 @default.
- W2894896110 cites W2781495894 @default.
- W2894896110 cites W2786384569 @default.
- W2894896110 cites W2791954561 @default.
- W2894896110 cites W4243165592 @default.
- W2894896110 cites W1876086267 @default.
- W2894896110 doi "https://doi.org/10.5858/arpa.2018-0216-ra" @default.
- W2894896110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30281371" @default.
- W2894896110 hasPublicationYear "2018" @default.
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