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• W2894910686 abstract "1. Abstract 1.1 Introduction: Atherosclerotic lesions of carotid and large cerebral vessels are animportant cause of stroke, which leads to a higher risk of early recurrentischemia than any other stroke subtype. Extracranial ultrasound and Transcranial Dopplerography (TCD) in triplex mode is anon-invasive approach to obtaining qualitative changes in the carotid andmiddle cerebral arteries, and the quantitative parameters of the blood flow inthem. 1.2 Objective: Ultrasonographic assessment of carotid and middle cerebral arteries inpatients with hemispheric stroke, caused by atherosclerosis of this vessels. 1.3 Materials and Methods: A retrospective analysis of the results of carotid ultrasound and Transcranial Dopplerography(TCD) of the Middle Cerebral Artery (MCA) was performed in 134 patients withhemispheric Ischemic Strokes (IS) of large vessel subtype. The age of thesubjects was 41-80 years, among them 65 (48,5%) men and 69 (51,5%) women. Themaximum intima-media thickness, atherosclerotic plaque sizes and types, carotidstenosis degree, middle cerebral artery diameter and stenosis were determined.The comparative group consisted of 78 patients without previoustransient ischemic attack or ischemic stroke. <span style=font-size:10.0pt;font-family: times= new= roman,serif;mso-fareast-font-family:times= roman=>1.4 Results: 112 (83.6%) patients with stroke had a localthickening of the Internal Carotid Artery (ICA) wall more than 1,1 mm, wallcalcification and atherosclerotic plaques of various types. Stenosis of the ICAin the range of 31-50% was noted in 43 (32.1%) patients, 51-70% in 35 (26.15%)patients, more than 70 % - in 12 (9.0%) patients, respectively. A soft plaque on the wall of the ICA was recorded in13 (9.7%) patients. Carotid artery wall calcification was noted in 32 (23.9%)cases - in 21 of them it caused stenosis of the artery lumen in the range of31-50%. Isolated calcified plaques were recorded in 27 (20.1%) cases. In 19cases they contributed to the stenosis of the ICA in the range of 31-50%.Stenosis of the lumen of the ICA more than 50% was caused by a local thickeningof the oppositely located walls of the ICA in combination with calcification.Ulcerated plaques were diagnosed in 14 (10.4%) patients with stroke -significantly more often than in the comparative group. Atheroscleroticchanges in the walls of the Common Carotid Artery (ССA) were noted in 109(81.3%) patients with stroke. Stenosis of the CCA in range of 31-50% was notedin 57 (42.5%) patients, 51-70% in 23 (17.2%) patients. Large plaques causingstenosis of the CCA lumen more than 50% were recorded in 36 (26.9%) cases. In25 cases, these plaques were soft, homogeneous, in 11 cases - non-uniform withthe presence of calcification sites. With TCD a good visualization of the MCA was performed in 98 (73.1%)patients, and satisfactory in 27 (20.1%) patients. In 9 (6.7%) patients, theMCA was not visualized at all, but the Doppler spectrum without visualizationof the artery was obtained in 7 of them. In TCD stenosis of the middle cerebralartery (> 50%) was diagnosed in 28 (20.9) patients. 1.5 Conclusion: The relationshipbetween the nature of atherosclerotic plaque, the degree of stenosis of theinternal carotid artery and the frequency of occurrence of ischemic stroke areestablished. Ulcerated and embologenic plaques in the carotid arteries,stenosis of the internal carotid artery more than 70% increase the risk ofischemic stroke. Hemodynamically significant stenosis of the middle cerebralartery can be diagnosed by color Doppler in more than 70% of patients withischemic stroke. 2. Keywords <span style=font-size:10.0pt;font-family: times= new= roman,serif=>: <span style=font-size:10.0pt;font-family: times= new= roman,serif=> Carotid Atherosclerosis; Carotid Stenosis;Extracranial Ultrasonography; Ishemic Stroke; Transcranial Dopplerography" @default.
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• W2894910686 date "2018-07-05" @default.
• W2894910686 modified "2023-09-27" @default.
• W2894910686 title "Ultrasonographic Characteristics of Carotid and Middle Cerebral Arteries in Patients with Ischemic Stroke" @default.
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