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- W2894914225 abstract "Introduction: It is known that Gadolinium Ethoxybenzyl Diethylenetriamine Pentaacetic Acid enhanced magnetic resonance imaging (EOB-MRI) improved the detection of hepatocellular carcinoma (HCC). In preoperative MRI, additional non-hypervascular hypointense nodule (ANHHN) is found sometimes, however there are only few studies about prognosis of curative treatments of ANHHN and primary HCC lesion together. Method and materials: We retrospectively reviewed medical records and preoperative images of 441 HCC patients who underwent surgical curative treatment at Yonsei Cancer Center from January 2008 to December 2012. Results: Among 441 patients, 279 were diagnosed HCC with Computed Tomography (CT) and MRI both, 79 patients were diagnosed with additional EOB-MRI because of uncertain diagnosis in CT, and 83 patients were founded additional lesion in EOB-MRI. Overall survival analysis showed no statistically difference between the single and addtional lesion groups, and there was a significant difference between the single and multiple HCC groups. However, in disease-free survival analysis, there was no difference between multiple HCC and addtional lesion groups, but only single HCC group showed statistically favorable results. Single HCC group (median 80 months, 95% CI [64.002-89.986]) vs multiple HCC group (median 24 months, 95% CI [17.483-30.517]) vs ANHHN group (median 32 months, 95% CI [21.135-42.865]). Conclusion: Patients with ANHHN showed similar disease-free survival compared to multiple HCC, but overall survival was similar to that of single HCC. Therefore, a single overt HCC with ANHHN should be considered a surgical candidate and combined active treatment is recommended if their liver function is allowed." @default.
- W2894914225 created "2018-10-12" @default.
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- W2894914225 date "2018-09-01" @default.
- W2894914225 modified "2023-09-26" @default.
- W2894914225 title "Prognosis after curative treatments of additional non-hypervascular hypointense nodules detected by EOB-MRI in a resectable hepatocellular carcinoma" @default.
- W2894914225 doi "https://doi.org/10.1016/j.hpb.2018.06.2694" @default.
- W2894914225 hasPublicationYear "2018" @default.
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