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- W2894931114 abstract "Introduction: Previous study indicated that clinical scoring model (CSM) could accurately predict the severity of cirrhosis. This study aimed to compare the therapeutic efficacy of liver resection (LR) and percutaneous microwave coagulation therapy(PMCT) for solitary and small hepatocellular carcinoma (HCC) using CSM. Methods: In this study, 228 patients with single HCC ≤3 cm and Child-Pugh A liver function were retrospectively reviewed. Among these patients, 131 patients underwent LR, and 97 patients received PMCT. The short and long-term outcomes were compared between the two procedures. Results: There was no 90-days mortality in either group. Major complications were significantly more frequent in the LR group compared to the PMCT group (18.8% vs 4.6%, p=0.003). The 1-, 3-, and 5-year overall survival(OS) rates for the LR group and PMCT group were 97.2%, 91.6%, 65.2% and 90.1%, 72.4%, 42%, respectively ( p=0.006). The 1-, 3-, and 5-year disease-free survival (DFS) rates for the LR group and PMCT group were 95.4%, 74.5%, 51.7% and 83.4%, 51.2%, 31.5%,respectively (p=0.004). Nevertheless, subgroup analyses suggested that HCC patients with CSM score ≥4, PMCT may provide long-term outcomes that are similar to LR and lower complications. Conclusions: LR may provide better OS and DFS rates than PMCT for solitary HCC≤ 3 cm and Child-Pugh A liver function. PMCT should be optimal choice for HCC patients with CSM score ≥4." @default.
- W2894931114 created "2018-10-12" @default.
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- W2894931114 date "2018-09-01" @default.
- W2894931114 modified "2023-09-27" @default.
- W2894931114 title "Clinical scoring model determines surgical modality for solitarya and small hepatocellular carcinoma with child-pugh a liver function" @default.
- W2894931114 doi "https://doi.org/10.1016/j.hpb.2018.06.2740" @default.
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