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- W2894935735 abstract "Introduction: Radio frequency ablation (RFA) for hepatocellular carcinoma (HCC) were the importance therapeutic strategy. The gross classification by The General Rules of the Clinical and Pathological Study of Primary Liver Cancer and tumor size were very important for HCC therapy. For our surgical outcome and result of pathology based on the gross classification from 1990 to 1994, our RFA indication was less than 30 mm and simple nodular type (SN) or small nodular type with indistinct margin (SNIM). We presented that there were no significant difference of rate of disease-free (DFS) and overall survival rates (OS) between HR and RFA. This time, we studied relations between outcome of RFA and tumor marker AFP. Methods: 40 cases checked level of AFP two time before operation, undergoing first therapy by RFA from 2009 to 2012 were studied. We evaluated DSF, OS by a group with increasing of level of AFP (UP group) or not increasing (non-UP group). Results: In the group (n=22) and non-UP group (n=18), level of AFP at first time were 2-191 (median: 17) and 3-102 ng/ml (median: 7.5), level of AFP at second time were 3-298 (median: 18), 2-65 ng/ml (median: 7). The 5 years DSF of UP group or non-UP group were 18.8%, 27.3% (p=0.645), and the 5 OS were 48.1%, 84.2% (p=0.04). Conclusion: In RFA as first therapy for SN- or SNIM-type HCC (< 30 mm, single nodule), it was suggested :that some increasing of the level of AFP before operation had relation to OS." @default.
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- W2894935735 date "2018-09-01" @default.
- W2894935735 modified "2023-10-03" @default.
- W2894935735 title "Some increasing of the level of AFP before operation had relation to overall survival rates in rfa as first therapy for small HCC" @default.
- W2894935735 doi "https://doi.org/10.1016/j.hpb.2018.06.2679" @default.
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