FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894948944> ?p ?o ?g. }

• W2894948944 abstract "Breast cancer (BC) is the most frequently diagnosed malignant tumor in women worldwide, and the development of new molecules associated with BC is essential for the management of this disease. RAS and EF-hand domain-containing (RASEF) encodes the GTPase enzyme that belongs to the Rab family. Although the effects of this gene have been reported in several malignant tumor types, the role of RASEF in BC has not been completely elucidated. The aim of the present study was to investigate the importance of RASEF expression in BC. RASEF mRNA expression levels were evaluated in BC and non-cancerous mammary cell lines. The association between RASEF mRNA expression levels and clinicopathological factors in 167 patients with BC were then determined. Among the 13 examined BC cell lines, ER-negative/HER2-negative cell lines expressed lower RASEF mRNA levels, when compared with the other examined cell lines (P=0.014). Of the 167 patients examined, patients with negative hormone receptor status exhibited significantly lower RASEF mRNA expression levels (P<0.001). In addition low RASEF expression in BC tissues was associated with negative estrogen receptor status (P<0.001), negative progesterone receptor status (P<0.001), and triple-negative status (P<0.001). Additionally, although the differences were not statistically significant, patients with low RASEF expression levels exhibited poorer disease-free survival (P=0.123) and overall survival (P=0.086) than other patients. The results of the present study indicate that RASEF mRNA expression levels are associated with hormone receptor status in BC." @default.
• W2894948944 created "2018-10-12" @default.
• W2894948944 creator A5004655295 @default.
• W2894948944 creator A5012115431 @default.
• W2894948944 creator A5014646068 @default.
• W2894948944 creator A5014954218 @default.
• W2894948944 creator A5018146056 @default.
• W2894948944 creator A5018268432 @default.
• W2894948944 creator A5021773480 @default.
• W2894948944 creator A5026524817 @default.
• W2894948944 creator A5031632066 @default.
• W2894948944 creator A5036527872 @default.
• W2894948944 creator A5038954107 @default.
• W2894948944 creator A5041744762 @default.
• W2894948944 creator A5045259409 @default.
• W2894948944 creator A5067378665 @default.
• W2894948944 creator A5086122888 @default.
• W2894948944 creator A5089181888 @default.
• W2894948944 date "2018-10-03" @default.
• W2894948944 modified "2023-09-28" @default.
• W2894948944 title "RASEF expression correlates with hormone receptor status in breast cancer" @default.
• W2894948944 cites W1982769068 @default.
• W2894948944 cites W1987813585 @default.
• W2894948944 cites W1990065094 @default.
• W2894948944 cites W1991262919 @default.
• W2894948944 cites W1992273782 @default.
• W2894948944 cites W2009336701 @default.
• W2894948944 cites W2015219390 @default.
• W2894948944 cites W2044702943 @default.
• W2894948944 cites W2059678866 @default.
• W2894948944 cites W2063874882 @default.
• W2894948944 cites W2076914444 @default.
• W2894948944 cites W2096316763 @default.
• W2894948944 cites W2100618663 @default.
• W2894948944 cites W2103157496 @default.
• W2894948944 cites W2114941442 @default.
• W2894948944 cites W2126945850 @default.
• W2894948944 cites W2137153762 @default.
• W2894948944 cites W2148345265 @default.
• W2894948944 cites W2155468833 @default.
• W2894948944 cites W2156323044 @default.
• W2894948944 cites W2164387214 @default.
• W2894948944 cites W2170915948 @default.
• W2894948944 cites W2173858545 @default.
• W2894948944 cites W2418889459 @default.
• W2894948944 cites W2436425944 @default.
• W2894948944 cites W2467685370 @default.
• W2894948944 cites W2523763608 @default.
• W2894948944 cites W2604193981 @default.
• W2894948944 cites W2727474048 @default.
• W2894948944 cites W2739217805 @default.
• W2894948944 cites W4249688612 @default.
• W2894948944 doi "https://doi.org/10.3892/ol.2018.9542" @default.
• W2894948944 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6256290" @default.
• W2894948944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30546460" @default.
• W2894948944 hasPublicationYear "2018" @default.
• W2894948944 type Work @default.
• W2894948944 sameAs 2894948944 @default.
• W2894948944 citedByCount "3" @default.
• W2894948944 countsByYear W28949489442020 @default.
• W2894948944 countsByYear W28949489442021 @default.
• W2894948944 countsByYear W28949489442022 @default.
• W2894948944 crossrefType "journal-article" @default.
• W2894948944 hasAuthorship W2894948944A5004655295 @default.
• W2894948944 hasAuthorship W2894948944A5012115431 @default.
• W2894948944 hasAuthorship W2894948944A5014646068 @default.
• W2894948944 hasAuthorship W2894948944A5014954218 @default.
• W2894948944 hasAuthorship W2894948944A5018146056 @default.
• W2894948944 hasAuthorship W2894948944A5018268432 @default.
• W2894948944 hasAuthorship W2894948944A5021773480 @default.
• W2894948944 hasAuthorship W2894948944A5026524817 @default.
• W2894948944 hasAuthorship W2894948944A5031632066 @default.
• W2894948944 hasAuthorship W2894948944A5036527872 @default.
• W2894948944 hasAuthorship W2894948944A5038954107 @default.
• W2894948944 hasAuthorship W2894948944A5041744762 @default.
• W2894948944 hasAuthorship W2894948944A5045259409 @default.
• W2894948944 hasAuthorship W2894948944A5067378665 @default.
• W2894948944 hasAuthorship W2894948944A5086122888 @default.
• W2894948944 hasAuthorship W2894948944A5089181888 @default.
• W2894948944 hasBestOaLocation W28949489441 @default.
• W2894948944 hasConcept C121608353 @default.
• W2894948944 hasConcept C126322002 @default.
• W2894948944 hasConcept C134018914 @default.
• W2894948944 hasConcept C170493617 @default.
• W2894948944 hasConcept C23589133 @default.
• W2894948944 hasConcept C2781018059 @default.
• W2894948944 hasConcept C29537977 @default.
• W2894948944 hasConcept C502942594 @default.
• W2894948944 hasConcept C530470458 @default.
• W2894948944 hasConcept C67082663 @default.
• W2894948944 hasConcept C71315377 @default.
• W2894948944 hasConcept C71924100 @default.
• W2894948944 hasConcept C84606932 @default.
• W2894948944 hasConcept C86803240 @default.
• W2894948944 hasConcept C98717036 @default.
• W2894948944 hasConceptScore W2894948944C121608353 @default.
• W2894948944 hasConceptScore W2894948944C126322002 @default.
• W2894948944 hasConceptScore W2894948944C134018914 @default.
• W2894948944 hasConceptScore W2894948944C170493617 @default.
• W2894948944 hasConceptScore W2894948944C23589133 @default.

• next