Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894953165> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2894953165 abstract "Abstract Background Since the initial report of the finished human genome reference sequence in 2004, 1 cancer genetics research has focused on using this reference as a template for characterizing the somatic genomic alterations that underlie cancer's development and the germline genomic alterations that underlie human susceptibility to develop cancer. Because technology has enabled a transition from polymerase chain reaction (PCR)–based mutation discovery, to microarray-based copy number detection, to massively parallel sequencing (MPS) assays that provide a comprehensive somatic landscape of the cancer genome, our understanding of cancer genome alterations has increased in scope while becoming increasingly refined. 2 Content Modern day cancer diagnostic assays have been devised based on the cumulative knowledge gained from large-scale cancer genomics discovery efforts. These studies of tens to thousands of cancers across many tissues of origin have catalogued the genomic landscape of human cancers by MPS and often included data from RNA expression and DNA methylation. This chapter outlines aspects of these molecular assays of solid tissue malignancies in the clinical setting that have been enabled by research-based discovery work over the past approximately 20 years." @default.
- W2894953165 created "2018-10-12" @default.
- W2894953165 creator A5054642128 @default.
- W2894953165 date "2018-01-01" @default.
- W2894953165 modified "2023-09-28" @default.
- W2894953165 title "Solid Tumor Genomics" @default.
- W2894953165 doi "https://doi.org/10.1016/b978-0-12-816061-9.00007-2" @default.
- W2894953165 hasPublicationYear "2018" @default.
- W2894953165 type Work @default.
- W2894953165 sameAs 2894953165 @default.
- W2894953165 citedByCount "0" @default.
- W2894953165 crossrefType "book-chapter" @default.
- W2894953165 hasAuthorship W2894953165A5054642128 @default.
- W2894953165 hasConcept C104317684 @default.
- W2894953165 hasConcept C109825262 @default.
- W2894953165 hasConcept C121608353 @default.
- W2894953165 hasConcept C13514818 @default.
- W2894953165 hasConcept C141231307 @default.
- W2894953165 hasConcept C189206191 @default.
- W2894953165 hasConcept C197077220 @default.
- W2894953165 hasConcept C205270622 @default.
- W2894953165 hasConcept C501734568 @default.
- W2894953165 hasConcept C51679486 @default.
- W2894953165 hasConcept C54355233 @default.
- W2894953165 hasConcept C70721500 @default.
- W2894953165 hasConcept C86803240 @default.
- W2894953165 hasConceptScore W2894953165C104317684 @default.
- W2894953165 hasConceptScore W2894953165C109825262 @default.
- W2894953165 hasConceptScore W2894953165C121608353 @default.
- W2894953165 hasConceptScore W2894953165C13514818 @default.
- W2894953165 hasConceptScore W2894953165C141231307 @default.
- W2894953165 hasConceptScore W2894953165C189206191 @default.
- W2894953165 hasConceptScore W2894953165C197077220 @default.
- W2894953165 hasConceptScore W2894953165C205270622 @default.
- W2894953165 hasConceptScore W2894953165C501734568 @default.
- W2894953165 hasConceptScore W2894953165C51679486 @default.
- W2894953165 hasConceptScore W2894953165C54355233 @default.
- W2894953165 hasConceptScore W2894953165C70721500 @default.
- W2894953165 hasConceptScore W2894953165C86803240 @default.
- W2894953165 hasLocation W28949531651 @default.
- W2894953165 hasOpenAccess W2894953165 @default.
- W2894953165 hasPrimaryLocation W28949531651 @default.
- W2894953165 hasRelatedWork W1483228480 @default.
- W2894953165 hasRelatedWork W151134776 @default.
- W2894953165 hasRelatedWork W1530621036 @default.
- W2894953165 hasRelatedWork W1920935675 @default.
- W2894953165 hasRelatedWork W1936243389 @default.
- W2894953165 hasRelatedWork W1965856472 @default.
- W2894953165 hasRelatedWork W1978937944 @default.
- W2894953165 hasRelatedWork W1979881273 @default.
- W2894953165 hasRelatedWork W2009811758 @default.
- W2894953165 hasRelatedWork W2076481272 @default.
- W2894953165 hasRelatedWork W2095893999 @default.
- W2894953165 hasRelatedWork W2103258359 @default.
- W2894953165 hasRelatedWork W2112961146 @default.
- W2894953165 hasRelatedWork W2161955640 @default.
- W2894953165 hasRelatedWork W2164418361 @default.
- W2894953165 hasRelatedWork W2354545445 @default.
- W2894953165 hasRelatedWork W2508012553 @default.
- W2894953165 hasRelatedWork W2620690700 @default.
- W2894953165 hasRelatedWork W3720132 @default.
- W2894953165 hasRelatedWork W963665113 @default.
- W2894953165 isParatext "false" @default.
- W2894953165 isRetracted "false" @default.
- W2894953165 magId "2894953165" @default.
- W2894953165 workType "book-chapter" @default.