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- W2894964653 abstract "Previous studies found divergent effects of aspirin use on prostate cancer incidence, potentially due to studies with short durations of aspirin use and insufficient adjustment for screening. A systematic review on the association between aspirin use ≥3 years and incident prostate cancer was performed in accordance with the PRISMA and MOOSE criteria. In the cohort studies, aspirin use for at least 3 years was associated with a lower incidence rate of prostate cancer (Odds ratio (OR) 0.88, 95% CI 0.80-0.97). No protective association was established for the case-control studies (OR 0.92, 95% CI 0.68–1.23). Subgroup analysis of advanced and aggressive cancers showed a protective association (OR 0.82, 95% CI 0.71-0.94 and OR 0.75, 95% CI 0.61-0.97). This synthesis of observational studies suggests a potential protective association between long term aspirin use and incident prostate cancer. The current literature is highly heterogenous and suffers from inconsistent aspirin dose definition and measurement." @default.
- W2894964653 created "2018-10-12" @default.
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- W2894964653 date "2018-12-01" @default.
- W2894964653 modified "2023-10-13" @default.
- W2894964653 title "Effect of long term aspirin use on the incidence of prostate cancer: A systematic review and meta-analysis" @default.
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- W2894964653 doi "https://doi.org/10.1016/j.critrevonc.2018.09.013" @default.
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