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• W2894965360 abstract "The past decade has seen incredible advances in the field of stem cell biology that have greatly improved our understanding of development and provided important insights into pathological processes. Transcription factors (TFs) play a central role in mediating stem cell proliferation, quiescence, and differentiation. One TF that contributes to these processes is Nuclear Factor One X (NFIX). Recently, NFIX activity has been shown to be essential in multiple organ systems and to have important translational impacts for human health. Here, we describe recent studies showing the contribution of NFIX to muscle development and muscular dystrophies, hematopoiesis, cancer, and neural stem cell biology, highlighting the importance of this knowledge in the development of therapeutic targets." @default.
• W2894965360 created "2018-10-12" @default.
• W2894965360 creator A5020780564 @default.
• W2894965360 creator A5028690309 @default.
• W2894965360 creator A5086214764 @default.
• W2894965360 date "2019-01-01" @default.
• W2894965360 modified "2023-10-08" @default.
• W2894965360 title "Nuclear Factor One X in Development and Disease" @default.
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• W2894965360 doi "https://doi.org/10.1016/j.tcb.2018.09.003" @default.
• W2894965360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30287093" @default.
• W2894965360 hasPublicationYear "2019" @default.
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