Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894968905> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2894968905 abstract "Background To evaluate the analytical performance of five commercial acetaminophen assays and select the best method for routine use. Methods Imprecision, accuracy, linearity, and interferences of three enzymatic assays (Beckman Coulter AU Paracetamol, Abbott MULTIGENT Acetaminophen, and Sekisui Acetaminophen L3K) and two immunoassay‐based assays (Beckman Coulter SYNCHRON ACTM (Acetaminophen) Reagent and Siemens SYVA Emit‐tox Acetaminophen) were evaluated on a Beckman Coulter AU680 chemistry analyzer. Hook effect for immunoassay‐based assays and recovery in ultrafiltrate for enzymatic methods were studied. Results Within‐run and between‐run imprecision of the enzymatic assays ranged 0.26%‐0.82% and 0.53%‐2.86%, respectively, while that for the immunoassay‐based methods ranged 0.96%‐6.34% and 1.50%‐11.33%, respectively. All assays except the SYNCHRON assay fell within the program analytical performance specifications (±20 µmol/L or 10%) for external quality assurance (EQA) samples, with the highest positive bias (31.7%) observed in the SYNCHRON assay. Icteric interference was demonstrated most significantly in the Abbott assay (up to 88 μmol/L positive bias in blank serum). The lipemic interference on the SYNCHRON was significant (up to 110% positive bias at level of 100 μmol/L). The immunoassay‐based methods were less susceptible to hemolytic interference, while the Abbott and AU assays were more susceptible to N‐acetylcysteine interference. Both immunoassay‐based methods showed no hook effect up to 18 000 μmol/L. Ultrafiltration recoveries for enzymatic methods were satisfactory, ranging from 80.0% ± 5.1% to 89.5% ± 3.0%. Conclusions Proportional bias was observed in the SYNCHRON assay, while the Siemens and Sekisui assays were minimally affected by bilirubin interferences." @default.
- W2894968905 created "2018-10-12" @default.
- W2894968905 creator A5023281727 @default.
- W2894968905 creator A5054328104 @default.
- W2894968905 creator A5057339120 @default.
- W2894968905 creator A5072566445 @default.
- W2894968905 creator A5074079624 @default.
- W2894968905 creator A5086470199 @default.
- W2894968905 creator A5087202559 @default.
- W2894968905 date "2018-10-04" @default.
- W2894968905 modified "2023-09-30" @default.
- W2894968905 title "Performance evaluation of five commercial assays for detection of acetaminophen" @default.
- W2894968905 cites W1963868566 @default.
- W2894968905 cites W1981477338 @default.
- W2894968905 cites W2011598573 @default.
- W2894968905 cites W2045514536 @default.
- W2894968905 cites W2093269952 @default.
- W2894968905 cites W2096839956 @default.
- W2894968905 cites W2256857306 @default.
- W2894968905 cites W2601005943 @default.
- W2894968905 cites W4237226120 @default.
- W2894968905 doi "https://doi.org/10.1002/jcla.22683" @default.
- W2894968905 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6818599" @default.
- W2894968905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30288787" @default.
- W2894968905 hasPublicationYear "2018" @default.
- W2894968905 type Work @default.
- W2894968905 sameAs 2894968905 @default.
- W2894968905 citedByCount "5" @default.
- W2894968905 countsByYear W28949689052020 @default.
- W2894968905 countsByYear W28949689052022 @default.
- W2894968905 countsByYear W28949689052023 @default.
- W2894968905 crossrefType "journal-article" @default.
- W2894968905 hasAuthorship W2894968905A5023281727 @default.
- W2894968905 hasAuthorship W2894968905A5054328104 @default.
- W2894968905 hasAuthorship W2894968905A5057339120 @default.
- W2894968905 hasAuthorship W2894968905A5072566445 @default.
- W2894968905 hasAuthorship W2894968905A5074079624 @default.
- W2894968905 hasAuthorship W2894968905A5086470199 @default.
- W2894968905 hasAuthorship W2894968905A5087202559 @default.
- W2894968905 hasBestOaLocation W28949689051 @default.
- W2894968905 hasConcept C159654299 @default.
- W2894968905 hasConcept C185592680 @default.
- W2894968905 hasConcept C203014093 @default.
- W2894968905 hasConcept C2780420688 @default.
- W2894968905 hasConcept C43617362 @default.
- W2894968905 hasConcept C50817676 @default.
- W2894968905 hasConcept C71924100 @default.
- W2894968905 hasConceptScore W2894968905C159654299 @default.
- W2894968905 hasConceptScore W2894968905C185592680 @default.
- W2894968905 hasConceptScore W2894968905C203014093 @default.
- W2894968905 hasConceptScore W2894968905C2780420688 @default.
- W2894968905 hasConceptScore W2894968905C43617362 @default.
- W2894968905 hasConceptScore W2894968905C50817676 @default.
- W2894968905 hasConceptScore W2894968905C71924100 @default.
- W2894968905 hasIssue "2" @default.
- W2894968905 hasLocation W28949689051 @default.
- W2894968905 hasLocation W28949689052 @default.
- W2894968905 hasLocation W28949689053 @default.
- W2894968905 hasOpenAccess W2894968905 @default.
- W2894968905 hasPrimaryLocation W28949689051 @default.
- W2894968905 hasRelatedWork W1970910281 @default.
- W2894968905 hasRelatedWork W1994033534 @default.
- W2894968905 hasRelatedWork W2000793212 @default.
- W2894968905 hasRelatedWork W2008373365 @default.
- W2894968905 hasRelatedWork W2034256531 @default.
- W2894968905 hasRelatedWork W2069842851 @default.
- W2894968905 hasRelatedWork W2079372671 @default.
- W2894968905 hasRelatedWork W2084401751 @default.
- W2894968905 hasRelatedWork W2091822078 @default.
- W2894968905 hasRelatedWork W2415923358 @default.
- W2894968905 hasVolume "33" @default.
- W2894968905 isParatext "false" @default.
- W2894968905 isRetracted "false" @default.
- W2894968905 magId "2894968905" @default.
- W2894968905 workType "article" @default.