FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895027077> ?p ?o ?g. }

• W2895027077 abstract "ABO-incompatible living related kidney transplantation (ABO-iLKT) has increased the possibilities for kidney transplantation in patients with end stage renal disease. Due to advancements in immunosuppressive agents and the identification of immunological conditions following ABO-iLKT, this transplantation technique has achieved the same success rate as ABO-compatible LKT. However, some patients continue to generate anti-blood type antibodies, despite conventional immunosuppressant treatment.A 60-year-old man was referred to our hospital for kidney transplantation. The proposed transplant was ABO incompatible, from a donor with blood-type A to a recipient with blood-type O. The recipient's anti-A blood-type IgG antibody titer was measured at 4096-fold dilution. Following desensitization therapy, including mycophenolate mofetil (MMF) 750 mg/day for 3 months, intravenous Rituximab 200 mg, and two sessions of double filtration plasmapheresis, the anti-A blood-type IgG antibody titer decreased to only 516-fold dilution and did not meet our target of less than 128-fold dilution. MMF was thus continued for an additional 4 months and four additional sessions of plasmapheresis were undertaken. Following these interventions, antibody titers decreased to 128-fold dilution and ABO-iLKT was performed. Following transplant, antibody-mediated rejection was not observed and renal function was preserved. However, a post-operative renal biopsy 1.5 months later showed evidence of T-cell-mediated rejection IB. The patient was treated with steroids, with no increase in serum creatinine.Our findings suggest that the long-term single MMF desensitization therapy could be a suitable option for ABO-iLKT with high refractory and rebound anti-blood type antibody. Further studies are required to establish the optimal immunosuppression regimen to control B cell- mediated immunity in ABO-iLKT." @default.
• W2895027077 created "2018-10-12" @default.
• W2895027077 creator A5006111506 @default.
• W2895027077 creator A5022478812 @default.
• W2895027077 creator A5025729327 @default.
• W2895027077 creator A5038105097 @default.
• W2895027077 creator A5044574879 @default.
• W2895027077 creator A5046859907 @default.
• W2895027077 creator A5063467149 @default.
• W2895027077 creator A5073433877 @default.
• W2895027077 creator A5091311343 @default.
• W2895027077 date "2018-10-05" @default.
• W2895027077 modified "2023-10-06" @default.
• W2895027077 title "Long-term desensitization for ABO-incompatible living related kidney transplantation recipients with high refractory and rebound anti-blood type antibody: case report" @default.
• W2895027077 cites W1571769103 @default.
• W2895027077 cites W1598727077 @default.
• W2895027077 cites W1652931526 @default.
• W2895027077 cites W1720974273 @default.
• W2895027077 cites W1957503569 @default.
• W2895027077 cites W1973433723 @default.
• W2895027077 cites W1976465529 @default.
• W2895027077 cites W1990798689 @default.
• W2895027077 cites W1996853835 @default.
• W2895027077 cites W2014009378 @default.
• W2895027077 cites W2023026125 @default.
• W2895027077 cites W2026399893 @default.
• W2895027077 cites W2036650250 @default.
• W2895027077 cites W2039673503 @default.
• W2895027077 cites W2054552187 @default.
• W2895027077 cites W2068681520 @default.
• W2895027077 cites W2076501076 @default.
• W2895027077 cites W2088401889 @default.
• W2895027077 cites W2092628378 @default.
• W2895027077 cites W2094473847 @default.
• W2895027077 cites W2107783558 @default.
• W2895027077 cites W226632190 @default.
• W2895027077 cites W2341675640 @default.
• W2895027077 cites W2461733144 @default.
• W2895027077 cites W2606452793 @default.
• W2895027077 cites W291902516 @default.
• W2895027077 doi "https://doi.org/10.1186/s12882-018-1053-8" @default.
• W2895027077 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6173835" @default.
• W2895027077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30290778" @default.
• W2895027077 hasPublicationYear "2018" @default.
• W2895027077 type Work @default.
• W2895027077 sameAs 2895027077 @default.
• W2895027077 citedByCount "3" @default.
• W2895027077 countsByYear W28950270772018 @default.
• W2895027077 countsByYear W28950270772019 @default.
• W2895027077 crossrefType "journal-article" @default.
• W2895027077 hasAuthorship W2895027077A5006111506 @default.
• W2895027077 hasAuthorship W2895027077A5022478812 @default.
• W2895027077 hasAuthorship W2895027077A5025729327 @default.
• W2895027077 hasAuthorship W2895027077A5038105097 @default.
• W2895027077 hasAuthorship W2895027077A5044574879 @default.
• W2895027077 hasAuthorship W2895027077A5046859907 @default.
• W2895027077 hasAuthorship W2895027077A5063467149 @default.
• W2895027077 hasAuthorship W2895027077A5073433877 @default.
• W2895027077 hasAuthorship W2895027077A5091311343 @default.
• W2895027077 hasBestOaLocation W28950270771 @default.
• W2895027077 hasConcept C126322002 @default.
• W2895027077 hasConcept C126894567 @default.
• W2895027077 hasConcept C159641895 @default.
• W2895027077 hasConcept C159654299 @default.
• W2895027077 hasConcept C170493617 @default.
• W2895027077 hasConcept C176080213 @default.
• W2895027077 hasConcept C184113351 @default.
• W2895027077 hasConcept C203014093 @default.
• W2895027077 hasConcept C2778842783 @default.
• W2895027077 hasConcept C2779779143 @default.
• W2895027077 hasConcept C2780303639 @default.
• W2895027077 hasConcept C2780653079 @default.
• W2895027077 hasConcept C2911091166 @default.
• W2895027077 hasConcept C71924100 @default.
• W2895027077 hasConcept C90924648 @default.
• W2895027077 hasConceptScore W2895027077C126322002 @default.
• W2895027077 hasConceptScore W2895027077C126894567 @default.
• W2895027077 hasConceptScore W2895027077C159641895 @default.
• W2895027077 hasConceptScore W2895027077C159654299 @default.
• W2895027077 hasConceptScore W2895027077C170493617 @default.
• W2895027077 hasConceptScore W2895027077C176080213 @default.
• W2895027077 hasConceptScore W2895027077C184113351 @default.
• W2895027077 hasConceptScore W2895027077C203014093 @default.
• W2895027077 hasConceptScore W2895027077C2778842783 @default.
• W2895027077 hasConceptScore W2895027077C2779779143 @default.
• W2895027077 hasConceptScore W2895027077C2780303639 @default.
• W2895027077 hasConceptScore W2895027077C2780653079 @default.
• W2895027077 hasConceptScore W2895027077C2911091166 @default.
• W2895027077 hasConceptScore W2895027077C71924100 @default.
• W2895027077 hasConceptScore W2895027077C90924648 @default.
• W2895027077 hasIssue "1" @default.
• W2895027077 hasLocation W28950270771 @default.
• W2895027077 hasLocation W28950270772 @default.
• W2895027077 hasLocation W28950270773 @default.
• W2895027077 hasLocation W28950270774 @default.
• W2895027077 hasOpenAccess W2895027077 @default.
• W2895027077 hasPrimaryLocation W28950270771 @default.
• W2895027077 hasRelatedWork W1481414706 @default.
• W2895027077 hasRelatedWork W2038277169 @default.
• W2895027077 hasRelatedWork W2587983904 @default.

• next