Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895046502> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2895046502 endingPage "e646" @default.
- W2895046502 startingPage "e640" @default.
- W2895046502 abstract "Both stereotactic radiosurgery (SRS) and fractionated radiation therapy (FRT) techniques are used for treatment of intracranial meningiomas with excellent local control (LC) rates. Although SRS techniques are convenient, toxicity including treatment-related edema can significantly impact patient quality of life. The long-term clinical outcomes of patients with magnetic resonance imaging (MRI)–defined meningiomas treated with radiation therapy (RT) alone are reported. The charts of 211 patients with meningiomas diagnosed by contrast-enhanced MRI treated with either SRS or FRT between 1991 and 2012 at a single institution were reviewed. Actuarial rates for LC and development of treatment-related radiographic edema (TRE) were determined by the Kaplan-Meier method. There were 211 patients who received radiation therapy for 223 lesions. Median follow-up was 5.7 years. Eleven patients experienced a local failure; of these, 2 were ultimately found to have pathologically proven metastatic carcinoma. Two- and 5-year LC was 97.8% and 94.6%, respectively, with no significant difference based on modality of therapy. Actuarial rate for development of TRE at 1 and 2 years was 30.1% and 34.6% for the SRS group and 1.6% and 2.5% for the FRT group, respectively (P < 0.001). RT alone using a limited margin is an effective treatment option for MRI-defined meningiomas and should be considered even without biopsy if surgery will present significant morbidity. Although LC with SRS versus FRT was comparable, FRT was associated with a significantly decreased risk of TRE." @default.
- W2895046502 created "2018-10-12" @default.
- W2895046502 creator A5013571534 @default.
- W2895046502 creator A5016594403 @default.
- W2895046502 creator A5022827643 @default.
- W2895046502 creator A5030707431 @default.
- W2895046502 creator A5032332424 @default.
- W2895046502 creator A5043541884 @default.
- W2895046502 creator A5080153222 @default.
- W2895046502 date "2019-01-01" @default.
- W2895046502 modified "2023-10-18" @default.
- W2895046502 title "Fractionated Radiotherapy Is Associated with Lower Rates of Treatment-Related Edema than Stereotactic Radiosurgery in Magnetic Resonance Imaging–Defined Meningiomas" @default.
- W2895046502 cites W1562000508 @default.
- W2895046502 cites W1965342128 @default.
- W2895046502 cites W1978648170 @default.
- W2895046502 cites W1983716488 @default.
- W2895046502 cites W2021283222 @default.
- W2895046502 cites W2023465389 @default.
- W2895046502 cites W2031363332 @default.
- W2895046502 cites W2043494567 @default.
- W2895046502 cites W2049571882 @default.
- W2895046502 cites W2064180091 @default.
- W2895046502 cites W2076834992 @default.
- W2895046502 cites W2095900366 @default.
- W2895046502 cites W2148977460 @default.
- W2895046502 cites W2158680624 @default.
- W2895046502 cites W2346289363 @default.
- W2895046502 cites W4211003749 @default.
- W2895046502 cites W4245392732 @default.
- W2895046502 doi "https://doi.org/10.1016/j.wneu.2018.09.179" @default.
- W2895046502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6407415" @default.
- W2895046502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30292026" @default.
- W2895046502 hasPublicationYear "2019" @default.
- W2895046502 type Work @default.
- W2895046502 sameAs 2895046502 @default.
- W2895046502 citedByCount "11" @default.
- W2895046502 countsByYear W28950465022019 @default.
- W2895046502 countsByYear W28950465022020 @default.
- W2895046502 countsByYear W28950465022021 @default.
- W2895046502 countsByYear W28950465022022 @default.
- W2895046502 countsByYear W28950465022023 @default.
- W2895046502 crossrefType "journal-article" @default.
- W2895046502 hasAuthorship W2895046502A5013571534 @default.
- W2895046502 hasAuthorship W2895046502A5016594403 @default.
- W2895046502 hasAuthorship W2895046502A5022827643 @default.
- W2895046502 hasAuthorship W2895046502A5030707431 @default.
- W2895046502 hasAuthorship W2895046502A5032332424 @default.
- W2895046502 hasAuthorship W2895046502A5043541884 @default.
- W2895046502 hasAuthorship W2895046502A5080153222 @default.
- W2895046502 hasBestOaLocation W28950465022 @default.
- W2895046502 hasConcept C126838900 @default.
- W2895046502 hasConcept C141071460 @default.
- W2895046502 hasConcept C143409427 @default.
- W2895046502 hasConcept C2778256017 @default.
- W2895046502 hasConcept C2780387249 @default.
- W2895046502 hasConcept C2780886150 @default.
- W2895046502 hasConcept C2989005 @default.
- W2895046502 hasConcept C509974204 @default.
- W2895046502 hasConcept C71924100 @default.
- W2895046502 hasConceptScore W2895046502C126838900 @default.
- W2895046502 hasConceptScore W2895046502C141071460 @default.
- W2895046502 hasConceptScore W2895046502C143409427 @default.
- W2895046502 hasConceptScore W2895046502C2778256017 @default.
- W2895046502 hasConceptScore W2895046502C2780387249 @default.
- W2895046502 hasConceptScore W2895046502C2780886150 @default.
- W2895046502 hasConceptScore W2895046502C2989005 @default.
- W2895046502 hasConceptScore W2895046502C509974204 @default.
- W2895046502 hasConceptScore W2895046502C71924100 @default.
- W2895046502 hasFunder F4320332161 @default.
- W2895046502 hasFunder F4320333204 @default.
- W2895046502 hasLocation W28950465021 @default.
- W2895046502 hasLocation W28950465022 @default.
- W2895046502 hasLocation W28950465023 @default.
- W2895046502 hasLocation W28950465024 @default.
- W2895046502 hasOpenAccess W2895046502 @default.
- W2895046502 hasPrimaryLocation W28950465021 @default.
- W2895046502 hasRelatedWork W1490990766 @default.
- W2895046502 hasRelatedWork W1966770639 @default.
- W2895046502 hasRelatedWork W2003467035 @default.
- W2895046502 hasRelatedWork W2077579868 @default.
- W2895046502 hasRelatedWork W2173310068 @default.
- W2895046502 hasRelatedWork W2277147420 @default.
- W2895046502 hasRelatedWork W2756955015 @default.
- W2895046502 hasRelatedWork W3032177237 @default.
- W2895046502 hasRelatedWork W4292594305 @default.
- W2895046502 hasRelatedWork W72122836 @default.
- W2895046502 hasVolume "121" @default.
- W2895046502 isParatext "false" @default.
- W2895046502 isRetracted "false" @default.
- W2895046502 magId "2895046502" @default.
- W2895046502 workType "article" @default.