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- W2895047963 abstract "This study aimed to assess the variation with age of fifty trace element contents in normal female thyroids The prevalence of thyroid dysfunction is higher in the elderly as compared to the younger population. An excess or deficiency of specific trace element contents in thyroid plays an important role in goitro- and carcinogenesis of this gland. Samples of the human thyroid were obtained from randomly selected autopsy specimens of 33 females (European-Caucasian) aged 3.5 to 87 years after a sudden death mainly from trauma. The mass fraction of trace elements in normal female thyroids was investigated using neutron activation analysis and inductively coupled plasma mass spectrometry. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for chemical element analysis. This work revealed that there is a statistically significant increase in Co, Cs, Fe, La, Pb, Rb, Sb, Se, Sn, Tl, and Zn mass fraction in the normal thyroid of female during a lifespan. Contents of such carcinogenic or potentially carcinogenic trace elements as Co, La, Pb, Sb, Sn, and Tl in thyroid of seniors are 5-10 times higher than those in thyroid of girls or young women. Results of the study showed that for elderly females there is a goitrogenic and carcinogenic association with elevated levels of thyroid parenchymal trace elements at least such as Co, Cs, Fe, La, Pb, Rb, Sb, Sn, Tl, and Zn." @default.
- W2895047963 created "2018-10-12" @default.
- W2895047963 creator A5067362841 @default.
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- W2895047963 date "2018-09-05" @default.
- W2895047963 modified "2023-09-28" @default.
- W2895047963 title "Quantitative Analysis of Age-related Variations of 50 Trace Element Contents in Thyroid of Females" @default.
- W2895047963 doi "https://doi.org/10.24294/ace.v0i0.840" @default.
- W2895047963 hasPublicationYear "2018" @default.
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