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- W2895056126 abstract "Celiac disease is an autoimmune enteropathy characterized by the presence of antigliadin antibodies and small intestinal mucosal injury, mediated by the adaptive immune system in response to gluten. Gastrointestinal symptoms typically include diarrhea, malabsorption/weight loss, and bloating/abdominal pain. Extra-intestinal symptoms often occur. The most commonly reported neurological syndromes are peripheral neuropathy, headache, and “gluten ataxia.” Gluten ataxia may occur in the setting of celiac disease or with non-celiac gluten sensitivity. Consistent with this being a cerebellar phenomenon, autopsy studies demonstrate inflammatory infiltration and Purkinje cell loss. Cerebellar atrophy as well as white matter abnormalities may be evident on MRI. Treatment is institution of a gluten-free diet. Intravenous immune globulin may also be helpful in select patients." @default.
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- W2895056126 date "2018-08-01" @default.
- W2895056126 modified "2023-09-22" @default.
- W2895056126 title "A Case of Cognitive Impairment and Ataxia" @default.
- W2895056126 doi "https://doi.org/10.1093/med/9780190693190.003.0012" @default.
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