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• W2895062022 endingPage "13594" @default.
• W2895062022 startingPage "13587" @default.
• W2895062022 abstract "The alkylation of C–H bonds with N-vinylphthalimide by a rhodium-catalyzed reaction of aromatic amides containing an 8-aminoquinoline moiety as the directing group is reported. N-Vinylphthalimide functions as a 2-aminoethylating reagent. The resulting alkylated products can be converted into 3,4-dihydroisoquinolin-1(2H)-one derivatives in a one-pot transformation. Deuterium-labeling experiments suggest that the reaction proceeds through a carbene mechanism." @default.
• W2895062022 created "2018-10-12" @default.
• W2895062022 creator A5023225667 @default.
• W2895062022 creator A5026772485 @default.
• W2895062022 date "2018-10-04" @default.
• W2895062022 modified "2023-10-06" @default.
• W2895062022 title "A Synthesis of 3,4-Dihydroisoquinolin-1(2H)-one via the Rhodium-Catalyzed Alkylation of Aromatic Amides with <i>N</i>-Vinylphthalimide" @default.
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• W2895062022 doi "https://doi.org/10.1021/acs.joc.8b02249" @default.
• W2895062022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30284828" @default.
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