FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895068265> ?p ?o ?g. }

• W2895068265 endingPage "1595" @default.
• W2895068265 startingPage "1585" @default.
• W2895068265 abstract "Renal mass lesions with a follicular architecture resembling atrophic kidney have been described, but their distinction from thyroid-like follicular carcinoma of the kidney remains controversial. We collected 8 cases of this purported “atrophic kidney”–like lesion to fully describe their clinical and histologic spectrum, their possible etiology, and to discuss their distinction from other renal neoplasms. Eight total cases were identified with patient ages ranging from 9 to 48 years (mean: 29 y; median: 28.5 y). Four patients were female and 4 were male. The tumors were unifocal and size ranged from 1.6 to 4.9 cm (mean: 3.4 cm; median: 3.4 cm). All 8 tumors had a remarkably similar histology. Each was enveloped by a smooth muscle rich capsule and had an overall low power “follicular” architecture. The luminal spaces of the “follicles” (or cysts) contained eosinophilic secretions and the lining epithelium was often flattened and atrophic, but some had more rounded cells with a distinctive hobnail arrangement. Many cysts contained discohesive round cells floating within the eosinophilic material, and some contained small intraluminal tufts with features of markedly atrophic glomeruli. Periodic acid-Schiff stains highlighted basement membrane material extending into these glomerular-like tufts, and some contained small distinct capillaries surrounded by endothelial cells, interspersed mesangial-like cells, and rare surrounding podocyte-like cells, providing additional evidence for glomerulocystic structures. Scattered calcifications were present within cysts (or within cyst walls) in varying numbers and were characterized by 2 types: psammoma body–like or more amorphous deposits. The tissue between cystic glomeruli contained predominantly small atrophic tubular structures, but collagenized stroma and smaller collapsed glomeruli were also present. The 2 tumors from the oldest 2 patients (48 and 39 y) had a more striking degree of stromal hyalinization. Immunohistochemically, the cyst lining cells had a predominant WT-positive/PAX-8 negative/CK7-negative phenotype, while tubules were typically WT-1 negative/PAX-8 positive/CK7-positive. Upon comparison to a control group of 10 kidneys containing incidental non–mass-forming glomerulocystic change, the morphologic features and immunophenotype were identical. To date, no patient has had any recurrence or aggressive clinical behavior based on follow status in 7 of 8 cases (follow-up range: 9 to 168 mo; median: 24 mo; mean: 40 mo). In summary, we describe the clinicopathologic features of 8 unique, benign “atrophic kidney”–like lesions that may simply represent a non-neoplastic form of organizing tubular atrophy and glomerulocystic change, and emphasize their distinction from thyroid-like follicular carcinoma of the kidney." @default.
• W2895068265 created "2018-10-12" @default.
• W2895068265 creator A5006631709 @default.
• W2895068265 creator A5007583682 @default.
• W2895068265 creator A5034716746 @default.
• W2895068265 creator A5038770194 @default.
• W2895068265 creator A5045150707 @default.
• W2895068265 creator A5049749003 @default.
• W2895068265 creator A5070192160 @default.
• W2895068265 creator A5071485060 @default.
• W2895068265 creator A5078972851 @default.
• W2895068265 creator A5090422201 @default.
• W2895068265 date "2018-12-01" @default.
• W2895068265 modified "2023-09-29" @default.
• W2895068265 title "“Atrophic Kidney”–like Lesion" @default.
• W2895068265 cites W1605575783 @default.
• W2895068265 cites W1963854739 @default.
• W2895068265 cites W1983228128 @default.
• W2895068265 cites W1986344981 @default.
• W2895068265 cites W1990291410 @default.
• W2895068265 cites W1990782643 @default.
• W2895068265 cites W1997536543 @default.
• W2895068265 cites W2003526230 @default.
• W2895068265 cites W2006414337 @default.
• W2895068265 cites W2036038574 @default.
• W2895068265 cites W2047498379 @default.
• W2895068265 cites W2048666206 @default.
• W2895068265 cites W2056244095 @default.
• W2895068265 cites W2060223397 @default.
• W2895068265 cites W2070233538 @default.
• W2895068265 cites W2079233013 @default.
• W2895068265 cites W2079501748 @default.
• W2895068265 cites W2081829830 @default.
• W2895068265 cites W2088985776 @default.
• W2895068265 cites W2096806980 @default.
• W2895068265 cites W2109160066 @default.
• W2895068265 cites W2111867681 @default.
• W2895068265 cites W2112199099 @default.
• W2895068265 cites W2139565424 @default.
• W2895068265 cites W2158219227 @default.
• W2895068265 cites W2160453337 @default.
• W2895068265 cites W2169380328 @default.
• W2895068265 cites W2344364145 @default.
• W2895068265 cites W2460244481 @default.
• W2895068265 cites W2501566241 @default.
• W2895068265 cites W2549602223 @default.
• W2895068265 cites W2602067579 @default.
• W2895068265 cites W2767623795 @default.
• W2895068265 doi "https://doi.org/10.1097/pas.0000000000001157" @default.
• W2895068265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30285996" @default.
• W2895068265 hasPublicationYear "2018" @default.
• W2895068265 type Work @default.
• W2895068265 sameAs 2895068265 @default.
• W2895068265 citedByCount "15" @default.
• W2895068265 countsByYear W28950682652019 @default.
• W2895068265 countsByYear W28950682652020 @default.
• W2895068265 countsByYear W28950682652021 @default.
• W2895068265 countsByYear W28950682652022 @default.
• W2895068265 countsByYear W28950682652023 @default.
• W2895068265 crossrefType "journal-article" @default.
• W2895068265 hasAuthorship W2895068265A5006631709 @default.
• W2895068265 hasAuthorship W2895068265A5007583682 @default.
• W2895068265 hasAuthorship W2895068265A5034716746 @default.
• W2895068265 hasAuthorship W2895068265A5038770194 @default.
• W2895068265 hasAuthorship W2895068265A5045150707 @default.
• W2895068265 hasAuthorship W2895068265A5049749003 @default.
• W2895068265 hasAuthorship W2895068265A5070192160 @default.
• W2895068265 hasAuthorship W2895068265A5071485060 @default.
• W2895068265 hasAuthorship W2895068265A5078972851 @default.
• W2895068265 hasAuthorship W2895068265A5090422201 @default.
• W2895068265 hasConcept C105702510 @default.
• W2895068265 hasConcept C134018914 @default.
• W2895068265 hasConcept C142724271 @default.
• W2895068265 hasConcept C2779758542 @default.
• W2895068265 hasConcept C2780091579 @default.
• W2895068265 hasConcept C2780597408 @default.
• W2895068265 hasConcept C2781156865 @default.
• W2895068265 hasConcept C71924100 @default.
• W2895068265 hasConcept C86803240 @default.
• W2895068265 hasConceptScore W2895068265C105702510 @default.
• W2895068265 hasConceptScore W2895068265C134018914 @default.
• W2895068265 hasConceptScore W2895068265C142724271 @default.
• W2895068265 hasConceptScore W2895068265C2779758542 @default.
• W2895068265 hasConceptScore W2895068265C2780091579 @default.
• W2895068265 hasConceptScore W2895068265C2780597408 @default.
• W2895068265 hasConceptScore W2895068265C2781156865 @default.
• W2895068265 hasConceptScore W2895068265C71924100 @default.
• W2895068265 hasConceptScore W2895068265C86803240 @default.
• W2895068265 hasIssue "12" @default.
• W2895068265 hasLocation W28950682651 @default.
• W2895068265 hasLocation W28950682652 @default.
• W2895068265 hasOpenAccess W2895068265 @default.
• W2895068265 hasPrimaryLocation W28950682651 @default.
• W2895068265 hasRelatedWork W140678246 @default.
• W2895068265 hasRelatedWork W1966846596 @default.
• W2895068265 hasRelatedWork W1974980412 @default.
• W2895068265 hasRelatedWork W1996950638 @default.
• W2895068265 hasRelatedWork W2034831011 @default.

• next