Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895083798> ?p ?o ?g. }
- W2895083798 endingPage "9515" @default.
- W2895083798 startingPage "9481" @default.
- W2895083798 abstract "This review presents an update on the current knowledge of the secondary metabolite potential of the major fungal species used in industrial biotechnology, i.e., Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei. These species have a long history of safe use for enzyme production. Like most microorganisms that exist in a challenging environment in nature, these fungi can produce a large variety and number of secondary metabolites. Many of these compounds present several properties that make them attractive for different industrial and medical applications. A description of all known secondary metabolites produced by these species is presented here. Mycotoxins are a very limited group of secondary metabolites that can be produced by fungi and that pose health hazards in humans and other vertebrates when ingested in small amounts. Some mycotoxins are species-specific. Here, we present scientific basis for (1) the definition of mycotoxins including an update on their toxicity and (2) the clarity on misclassification of species and their mycotoxin potential reported in literature, e.g., A. oryzae has been wrongly reported as an aflatoxin producer, due to misclassification of Aspergillus flavus strains. It is therefore of paramount importance to accurately describe the mycotoxins that can potentially be produced by a fungal species that is to be used as a production organism and to ensure that production strains are not capable of producing mycotoxins during enzyme production. This review is intended as a reference paper for authorities, companies, and researchers dealing with secondary metabolite assessment, risk evaluation for food or feed enzyme production, or considerations on the use of these species as production hosts." @default.
- W2895083798 created "2018-10-12" @default.
- W2895083798 creator A5006359706 @default.
- W2895083798 creator A5021559678 @default.
- W2895083798 creator A5028557780 @default.
- W2895083798 creator A5048036989 @default.
- W2895083798 creator A5077487249 @default.
- W2895083798 date "2018-10-06" @default.
- W2895083798 modified "2023-10-14" @default.
- W2895083798 title "Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei" @default.
- W2895083798 cites W103378508 @default.
- W2895083798 cites W10392240 @default.
- W2895083798 cites W106470263 @default.
- W2895083798 cites W1078014187 @default.
- W2895083798 cites W1270235818 @default.
- W2895083798 cites W1420976997 @default.
- W2895083798 cites W1493716876 @default.
- W2895083798 cites W1497889441 @default.
- W2895083798 cites W1547033011 @default.
- W2895083798 cites W1547891980 @default.
- W2895083798 cites W1554312516 @default.
- W2895083798 cites W1560471104 @default.
- W2895083798 cites W1566564355 @default.
- W2895083798 cites W1577880077 @default.
- W2895083798 cites W1578369216 @default.
- W2895083798 cites W1587528859 @default.
- W2895083798 cites W1596718820 @default.
- W2895083798 cites W1599960378 @default.
- W2895083798 cites W160160382 @default.
- W2895083798 cites W1643756615 @default.
- W2895083798 cites W169008966 @default.
- W2895083798 cites W1756131747 @default.
- W2895083798 cites W1794268913 @default.
- W2895083798 cites W1826293425 @default.
- W2895083798 cites W182741576 @default.
- W2895083798 cites W183099184 @default.
- W2895083798 cites W1845631646 @default.
- W2895083798 cites W1850010945 @default.
- W2895083798 cites W1856371146 @default.
- W2895083798 cites W1897374662 @default.
- W2895083798 cites W1953389048 @default.
- W2895083798 cites W1964501057 @default.
- W2895083798 cites W1964680319 @default.
- W2895083798 cites W1964829601 @default.
- W2895083798 cites W1965054959 @default.
- W2895083798 cites W1965127842 @default.
- W2895083798 cites W1965679720 @default.
- W2895083798 cites W1965694168 @default.
- W2895083798 cites W1966832052 @default.
- W2895083798 cites W1967243300 @default.
- W2895083798 cites W1968269586 @default.
- W2895083798 cites W1969531656 @default.
- W2895083798 cites W1970731470 @default.
- W2895083798 cites W1971441180 @default.
- W2895083798 cites W1972444713 @default.
- W2895083798 cites W1972667600 @default.
- W2895083798 cites W1972777695 @default.
- W2895083798 cites W1973900289 @default.
- W2895083798 cites W1973943676 @default.
- W2895083798 cites W1973948454 @default.
- W2895083798 cites W1974221702 @default.
- W2895083798 cites W1974861916 @default.
- W2895083798 cites W1974897143 @default.
- W2895083798 cites W1975736231 @default.
- W2895083798 cites W1976392461 @default.
- W2895083798 cites W1977177177 @default.
- W2895083798 cites W1977180652 @default.
- W2895083798 cites W1978543515 @default.
- W2895083798 cites W1978749493 @default.
- W2895083798 cites W1979180793 @default.
- W2895083798 cites W1979278060 @default.
- W2895083798 cites W1979670427 @default.
- W2895083798 cites W1982877322 @default.
- W2895083798 cites W1983779523 @default.
- W2895083798 cites W1984132593 @default.
- W2895083798 cites W1984220526 @default.
- W2895083798 cites W1984734657 @default.
- W2895083798 cites W1984752698 @default.
- W2895083798 cites W1985482877 @default.
- W2895083798 cites W1985836007 @default.
- W2895083798 cites W1986946453 @default.
- W2895083798 cites W1986984232 @default.
- W2895083798 cites W1987024972 @default.
- W2895083798 cites W1987407704 @default.
- W2895083798 cites W1988112668 @default.
- W2895083798 cites W1988486502 @default.
- W2895083798 cites W1988497640 @default.
- W2895083798 cites W1988601378 @default.
- W2895083798 cites W1988708592 @default.
- W2895083798 cites W1989243951 @default.
- W2895083798 cites W1989519916 @default.
- W2895083798 cites W1989858973 @default.
- W2895083798 cites W1990969694 @default.
- W2895083798 cites W1992370416 @default.
- W2895083798 cites W1992394945 @default.
- W2895083798 cites W1992534722 @default.
- W2895083798 cites W1992584883 @default.
- W2895083798 cites W1994082338 @default.