Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895093105> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2895093105 endingPage "S292" @default.
- W2895093105 startingPage "S292" @default.
- W2895093105 abstract "Introduction: Sphincter of Oddi laxity (SOL) has been proven a high risk factor of hepatolithiasis recurrence and Roux-en-Y hepaticojejunostomy is the most widely used intervention. However, no prospective studies have demonstrated its efficacy so far. Methods: In this single-center open-label randomized controlled trial, we randomly assigned hepatolithiasis patients with SOL to receive either Roux-en-Y hepaticojejunostomy (intervention group) or merely calculus removal (control group). The primary endpoint was recurrence of calculus. Results: Of the 110 patients who underwent randomization, 83 were included in the intention-to-treat analysis. At a median follow-up of 27 month, the primary-endpoint event occurred in 11 of the 43 patients (25.6%) in the intervention group as compared with 10 of the 40 patients (25.0%) in the control group (relative risk[RR], 1.023; 95% confidence interval [CI], 0.488 to 2.145; P=0.951). Cholangitis attack occurred in 8 patients (18.6%) in the intervention group and in 7 patients (17.5%) in the control group (RR, 1.063; 95% CI, 0.424 to 2.664; P=0.896). Cholangiocarcinoma occurred in 1 patients (2.3%) in the intervention group and in 2 patients (5.0%) in the control group (RR, 0.465; 95% CI, 0.044 to 4.934; P=0.607). Conclusion: Based on our current data, Roux-en-Y hepaticojejunostomy did not help prevent calculus recurrence in hepatolithiasis patients with SOL in the short-medium term. A larger sample size and a longer follow-up may be needed to evaluate the efficacy of Roux-en-Y hepaticojejunostomy in the treatment of hepatolithiasis. (ClinicalTrials.gov number, NCT01459549)." @default.
- W2895093105 created "2018-10-12" @default.
- W2895093105 creator A5000292144 @default.
- W2895093105 creator A5003319267 @default.
- W2895093105 creator A5004829334 @default.
- W2895093105 creator A5044014447 @default.
- W2895093105 creator A5074777324 @default.
- W2895093105 creator A5085378930 @default.
- W2895093105 date "2018-09-01" @default.
- W2895093105 modified "2023-10-15" @default.
- W2895093105 title "Will Roux-en-Y hepaticojejunostomy help prevent calculus recurrence in hepatolithiasis patient with sphincter of oddi laxity: an ongoing randomized controlled trial" @default.
- W2895093105 doi "https://doi.org/10.1016/j.hpb.2018.06.275" @default.
- W2895093105 hasPublicationYear "2018" @default.
- W2895093105 type Work @default.
- W2895093105 sameAs 2895093105 @default.
- W2895093105 citedByCount "0" @default.
- W2895093105 crossrefType "journal-article" @default.
- W2895093105 hasAuthorship W2895093105A5000292144 @default.
- W2895093105 hasAuthorship W2895093105A5003319267 @default.
- W2895093105 hasAuthorship W2895093105A5004829334 @default.
- W2895093105 hasAuthorship W2895093105A5044014447 @default.
- W2895093105 hasAuthorship W2895093105A5074777324 @default.
- W2895093105 hasAuthorship W2895093105A5085378930 @default.
- W2895093105 hasBestOaLocation W28950931051 @default.
- W2895093105 hasConcept C126322002 @default.
- W2895093105 hasConcept C141071460 @default.
- W2895093105 hasConcept C159110652 @default.
- W2895093105 hasConcept C168563851 @default.
- W2895093105 hasConcept C199343813 @default.
- W2895093105 hasConcept C203092338 @default.
- W2895093105 hasConcept C204243189 @default.
- W2895093105 hasConcept C2776909242 @default.
- W2895093105 hasConcept C2777002071 @default.
- W2895093105 hasConcept C2777686260 @default.
- W2895093105 hasConcept C2777891700 @default.
- W2895093105 hasConcept C44249647 @default.
- W2895093105 hasConcept C71924100 @default.
- W2895093105 hasConcept C82789193 @default.
- W2895093105 hasConceptScore W2895093105C126322002 @default.
- W2895093105 hasConceptScore W2895093105C141071460 @default.
- W2895093105 hasConceptScore W2895093105C159110652 @default.
- W2895093105 hasConceptScore W2895093105C168563851 @default.
- W2895093105 hasConceptScore W2895093105C199343813 @default.
- W2895093105 hasConceptScore W2895093105C203092338 @default.
- W2895093105 hasConceptScore W2895093105C204243189 @default.
- W2895093105 hasConceptScore W2895093105C2776909242 @default.
- W2895093105 hasConceptScore W2895093105C2777002071 @default.
- W2895093105 hasConceptScore W2895093105C2777686260 @default.
- W2895093105 hasConceptScore W2895093105C2777891700 @default.
- W2895093105 hasConceptScore W2895093105C44249647 @default.
- W2895093105 hasConceptScore W2895093105C71924100 @default.
- W2895093105 hasConceptScore W2895093105C82789193 @default.
- W2895093105 hasLocation W28950931051 @default.
- W2895093105 hasOpenAccess W2895093105 @default.
- W2895093105 hasPrimaryLocation W28950931051 @default.
- W2895093105 hasRelatedWork W2088544186 @default.
- W2895093105 hasRelatedWork W2094278111 @default.
- W2895093105 hasRelatedWork W2113780394 @default.
- W2895093105 hasRelatedWork W2235155022 @default.
- W2895093105 hasRelatedWork W2343654171 @default.
- W2895093105 hasRelatedWork W2584850773 @default.
- W2895093105 hasRelatedWork W3030276453 @default.
- W2895093105 hasRelatedWork W3116716503 @default.
- W2895093105 hasRelatedWork W4244057383 @default.
- W2895093105 hasRelatedWork W4244069386 @default.
- W2895093105 hasVolume "20" @default.
- W2895093105 isParatext "false" @default.
- W2895093105 isRetracted "false" @default.
- W2895093105 magId "2895093105" @default.
- W2895093105 workType "article" @default.