FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895094872> ?p ?o ?g. }

• W2895094872 endingPage "e12579" @default.
• W2895094872 startingPage "e12579" @default.
• W2895094872 abstract "As an important metabolic enzyme, it is necessary to investigate the genetic polymorphisms of CYP2J2 among healthy Tibetan individuals. Genetic polymorphisms of CYP2J2 could affect enzyme activity and lead to differences among individual responses to drugs.We sequenced the whole gene of CYP2J2 in 100 unrelated, healthy Tibetan volunteers from the Tibet Autonomous Region and screened for genetic variants in the promoters, introns, exons, and the 3'-UTR regions.We detected 4 novel genetic polymorphisms of the CYP2J2 gene. The allelic frequencies of CYP2D6*1 and *7 were 0.955 and 0.045, respectively. CYP2D6*1/*7 decreased the activity of CYP2J2 and was expressed in 9% of the sample population.Our results provided basic data about CYP2J2 polymorphisms in a Tibetan population, suggested that the enzymatic activities of CYP2J2 might be different within the ethnic group, and offered a theoretical basis for individualized medical treatment and drug genomics studies." @default.
• W2895094872 created "2018-10-12" @default.
• W2895094872 creator A5001660941 @default.
• W2895094872 creator A5010445257 @default.
• W2895094872 creator A5035292460 @default.
• W2895094872 creator A5047312662 @default.
• W2895094872 creator A5052596795 @default.
• W2895094872 creator A5078869065 @default.
• W2895094872 creator A5086058158 @default.
• W2895094872 date "2018-10-01" @default.
• W2895094872 modified "2023-09-25" @default.
• W2895094872 title "Genetic polymorphisms of the drug-metabolizing enzyme CYP2J2 in a Tibetan population" @default.
• W2895094872 cites W1976408418 @default.
• W2895094872 cites W2006383191 @default.
• W2895094872 cites W2009078912 @default.
• W2895094872 cites W2011455194 @default.
• W2895094872 cites W2012291194 @default.
• W2895094872 cites W2017706049 @default.
• W2895094872 cites W2019308980 @default.
• W2895094872 cites W2024662014 @default.
• W2895094872 cites W2037113953 @default.
• W2895094872 cites W2037340856 @default.
• W2895094872 cites W2041345281 @default.
• W2895094872 cites W2051429795 @default.
• W2895094872 cites W2078624050 @default.
• W2895094872 cites W2080417453 @default.
• W2895094872 cites W2084786467 @default.
• W2895094872 cites W2092442566 @default.
• W2895094872 cites W2092811430 @default.
• W2895094872 cites W2093486401 @default.
• W2895094872 cites W2107995531 @default.
• W2895094872 cites W2109099152 @default.
• W2895094872 cites W2111668019 @default.
• W2895094872 cites W2123454607 @default.
• W2895094872 cites W2126568266 @default.
• W2895094872 cites W2133191593 @default.
• W2895094872 cites W2147575903 @default.
• W2895094872 cites W2147945288 @default.
• W2895094872 cites W2224907889 @default.
• W2895094872 cites W67906366 @default.
• W2895094872 doi "https://doi.org/10.1097/md.0000000000012579" @default.
• W2895094872 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6200477" @default.
• W2895094872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30290621" @default.
• W2895094872 hasPublicationYear "2018" @default.
• W2895094872 type Work @default.
• W2895094872 sameAs 2895094872 @default.
• W2895094872 citedByCount "3" @default.
• W2895094872 countsByYear W28950948722020 @default.
• W2895094872 countsByYear W28950948722021 @default.
• W2895094872 countsByYear W28950948722023 @default.
• W2895094872 crossrefType "journal-article" @default.
• W2895094872 hasAuthorship W2895094872A5001660941 @default.
• W2895094872 hasAuthorship W2895094872A5010445257 @default.
• W2895094872 hasAuthorship W2895094872A5035292460 @default.
• W2895094872 hasAuthorship W2895094872A5047312662 @default.
• W2895094872 hasAuthorship W2895094872A5052596795 @default.
• W2895094872 hasAuthorship W2895094872A5078869065 @default.
• W2895094872 hasAuthorship W2895094872A5086058158 @default.
• W2895094872 hasBestOaLocation W28950948721 @default.
• W2895094872 hasConcept C101762097 @default.
• W2895094872 hasConcept C104317684 @default.
• W2895094872 hasConcept C135763542 @default.
• W2895094872 hasConcept C149737253 @default.
• W2895094872 hasConcept C150194340 @default.
• W2895094872 hasConcept C180754005 @default.
• W2895094872 hasConcept C2908647359 @default.
• W2895094872 hasConcept C33664856 @default.
• W2895094872 hasConcept C36823959 @default.
• W2895094872 hasConcept C37463918 @default.
• W2895094872 hasConcept C54355233 @default.
• W2895094872 hasConcept C55775858 @default.
• W2895094872 hasConcept C71924100 @default.
• W2895094872 hasConcept C86803240 @default.
• W2895094872 hasConcept C99454951 @default.
• W2895094872 hasConceptScore W2895094872C101762097 @default.
• W2895094872 hasConceptScore W2895094872C104317684 @default.
• W2895094872 hasConceptScore W2895094872C135763542 @default.
• W2895094872 hasConceptScore W2895094872C149737253 @default.
• W2895094872 hasConceptScore W2895094872C150194340 @default.
• W2895094872 hasConceptScore W2895094872C180754005 @default.
• W2895094872 hasConceptScore W2895094872C2908647359 @default.
• W2895094872 hasConceptScore W2895094872C33664856 @default.
• W2895094872 hasConceptScore W2895094872C36823959 @default.
• W2895094872 hasConceptScore W2895094872C37463918 @default.
• W2895094872 hasConceptScore W2895094872C54355233 @default.
• W2895094872 hasConceptScore W2895094872C55775858 @default.
• W2895094872 hasConceptScore W2895094872C71924100 @default.
• W2895094872 hasConceptScore W2895094872C86803240 @default.
• W2895094872 hasConceptScore W2895094872C99454951 @default.
• W2895094872 hasIssue "40" @default.
• W2895094872 hasLocation W28950948721 @default.
• W2895094872 hasLocation W28950948722 @default.
• W2895094872 hasLocation W28950948723 @default.
• W2895094872 hasLocation W28950948724 @default.
• W2895094872 hasOpenAccess W2895094872 @default.
• W2895094872 hasPrimaryLocation W28950948721 @default.
• W2895094872 hasRelatedWork W2020364677 @default.
• W2895094872 hasRelatedWork W2372413397 @default.

• next