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- W2895344763 abstract "Introduction: Patient comorbidities and body mass index (BMI) analysis for prediction of morbidity after pancreatoduodenectomy (PD). Methods: Prospective cohort analysis of consecutive PD performed during 2015, 2016 and 2017 at Rio-Hortega University Hospital (Valladolid, Spain). Outcomes: Overall morbidity (OM), Clavien ≥III morbidity, surgical site infection (SSI). Secondary outcomes: gastroparesis, pancreatic fistula (PF), hemorrhage (according to ISGPS: no appearance versus grades A, B and C). Rate of these outcomes were compared between cohort of patients presenting or not cardiovascular diseases (including hypertension), diabetes, hyperlipidemia, smoking. Cohorts according to ASA score (I, II versus III, IV) and BMI (<25 versus 25–30 versus >30) were also compared. Highest relative risks (RR) will be notified. Statistics: SPSS 24. Results: 41 patients (age 64.1 ± 10.5 years, 61% males). Rates of OM, Clavien ≥III morbidity, SSI, gastroparesis, PF, hemorrhage were respectively: 87.8%, 34.1%, 19.5%, 37.5%, 26.8%, 24.4%. Statistical differences between cohorts are shown in Table 1.EP02D-065 Table 1OMClavien ≥IIISSIGastroparesisPFHemorrhageDiabetes (no/yes)90% / 60% p=0.047n.s.n.s.n.s.35% / 0% p=0.039n.s.Hyperlipidemia (no/yes)n.s.22% / 50% ** p<0.10n.s.22% / 59% p=0.024n.s.n.s.Smoking (no/yes)n.s.n.s.n.s.n.s.n.s.17%/46% ** p<0.10ASA (I,II / III,IV)n.s.25% / 54% ** p<0.10n.s.25% / 67% p=0.0318% / 46% ** p<0.10n.s.BMI (<25 / 25-30 / >30)n.s.17% / 31% / 75% p=0.0196% / 19% / 50% p=0.04218% / 44% / 71% p=0.0346% / 37% / 50% p=0.02n.s.Highest RR (for BMI: <25 versus >30)BMI (RR=14.0, 95%CI=1.8-106.5)BMI (RR=16.0, 95%CI=1.4-185.4)BMI (RR=11.7, 95%CI=1.5 -91.5)BMI (RR=16.0, 95%CI=1.4-185.4) Open table in a new tab CV diseases did not obtain statistical significance for any outcome. Conclusion: Some baseline patient's comorbidities worsen outcomes after PD. Obesity has an important impact, increasing postoperative complications rate. Inconsistent results for diabetes as protective factor are probably due to low heterogeneous sample size." @default.
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- W2895344763 date "2018-09-01" @default.
- W2895344763 modified "2023-10-16" @default.
- W2895344763 title "Patient’s BMI and some baseline comorbidities are associated with complications after whipple procedure" @default.
- W2895344763 doi "https://doi.org/10.1016/j.hpb.2018.06.2153" @default.
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