FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895404077> ?p ?o ?g. }

• W2895404077 endingPage "6247" @default.
• W2895404077 startingPage "6235" @default.
• W2895404077 abstract "Novel nanomedical systems are being developed as multiple therapeutic modalities because the combinational therapies for cancer on a single platform can have larger chance to address tumor heterogeneity and drug resistance than any mono-therapeutic modality.In this study, photothermal therapy (PTT) and chemotherapy (CT) were combined to treat squamous cell carcinoma by using a novel type of noninvasive plaster composed of carboxylated-reduced graphene oxide (rGO-COOH), gold nanorods (Au NRs), and doxorubicin (DOX). Firstly, DOX was loaded onto rGO-COOH to form DOX_rGO-COOH. Then, the obtained DOX_rGO-COOH and Au NRs were co-assembled to obtain nanocomposite multilayer. rGO-COOH and Au NRs were combined together to obtain high light-to-heat conversion efficiency. Using them as photothermal agents for PTT and using DOX in rGO-COOH as an anticancer drug for CT, their synergistic combination therapy could be applicable practically.As a result, DOX_rGO-COOH/Au NRs showed higher photothermal effects than that showed by rGO-COOH or Au NRs alone. It also showed higher therapeutic effects than DOX_rGO-COOH (for CT) or Au nr (for PTT) alone. Moreover, the system can repeatedly produce heat and simultaneously stimulate the release of the encapsulated anticancer drug into the tumor upon being irradiated by near-infrared laser. In vivo experiments demonstrated that the squamous cell carcinoma-bearing mice treated with DOX_rGO-COOH/Au NRs were healthy for more than 60 days without tumor recurrence.The as-developed DOX_rGO-COOH/Au NRs plaster could be an effective, convenient, and noninvasive treatment option for treating superficial tumors." @default.
• W2895404077 created "2018-10-12" @default.
• W2895404077 creator A5008415127 @default.
• W2895404077 creator A5040171366 @default.
• W2895404077 creator A5053725057 @default.
• W2895404077 creator A5089774868 @default.
• W2895404077 date "2018-10-01" @default.
• W2895404077 modified "2023-10-17" @default.
• W2895404077 title "Nanocomposite plasters for the treatment of superficial tumors by chemo-photothermal combination therapy" @default.
• W2895404077 cites W1500801605 @default.
• W2895404077 cites W1504787922 @default.
• W2895404077 cites W1912498426 @default.
• W2895404077 cites W1929670869 @default.
• W2895404077 cites W1969868337 @default.
• W2895404077 cites W1977791081 @default.
• W2895404077 cites W1980107343 @default.
• W2895404077 cites W1988783116 @default.
• W2895404077 cites W1991610238 @default.
• W2895404077 cites W2004131005 @default.
• W2895404077 cites W2004164927 @default.
• W2895404077 cites W2005069692 @default.
• W2895404077 cites W2005626048 @default.
• W2895404077 cites W2012326766 @default.
• W2895404077 cites W2015883442 @default.
• W2895404077 cites W2030651891 @default.
• W2895404077 cites W2033156964 @default.
• W2895404077 cites W2033527100 @default.
• W2895404077 cites W2037315056 @default.
• W2895404077 cites W2039171477 @default.
• W2895404077 cites W2064394331 @default.
• W2895404077 cites W2070772667 @default.
• W2895404077 cites W2070921755 @default.
• W2895404077 cites W2085526373 @default.
• W2895404077 cites W2093833846 @default.
• W2895404077 cites W2094871883 @default.
• W2895404077 cites W2095121454 @default.
• W2895404077 cites W2096786458 @default.
• W2895404077 cites W2107944405 @default.
• W2895404077 cites W2134188586 @default.
• W2895404077 cites W2151467658 @default.
• W2895404077 cites W2164586886 @default.
• W2895404077 cites W2178692850 @default.
• W2895404077 cites W2192189823 @default.
• W2895404077 cites W2313248184 @default.
• W2895404077 cites W2314634653 @default.
• W2895404077 cites W2326443463 @default.
• W2895404077 cites W2329345175 @default.
• W2895404077 cites W2331721211 @default.
• W2895404077 cites W2396545253 @default.
• W2895404077 cites W2406897790 @default.
• W2895404077 cites W2410691776 @default.
• W2895404077 cites W2413326287 @default.
• W2895404077 cites W2530653483 @default.
• W2895404077 cites W2564209474 @default.
• W2895404077 cites W2568141451 @default.
• W2895404077 cites W2577934459 @default.
• W2895404077 cites W2594639002 @default.
• W2895404077 cites W2598092272 @default.
• W2895404077 cites W2613635666 @default.
• W2895404077 cites W2614402247 @default.
• W2895404077 cites W2762608270 @default.
• W2895404077 cites W2789765839 @default.
• W2895404077 doi "https://doi.org/10.2147/ijn.s170209" @default.
• W2895404077 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6188105" @default.
• W2895404077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30349247" @default.
• W2895404077 hasPublicationYear "2018" @default.
• W2895404077 type Work @default.
• W2895404077 sameAs 2895404077 @default.
• W2895404077 citedByCount "10" @default.
• W2895404077 countsByYear W28954040772019 @default.
• W2895404077 countsByYear W28954040772020 @default.
• W2895404077 countsByYear W28954040772021 @default.
• W2895404077 countsByYear W28954040772022 @default.
• W2895404077 crossrefType "journal-article" @default.
• W2895404077 hasAuthorship W2895404077A5008415127 @default.
• W2895404077 hasAuthorship W2895404077A5040171366 @default.
• W2895404077 hasAuthorship W2895404077A5053725057 @default.
• W2895404077 hasAuthorship W2895404077A5089774868 @default.
• W2895404077 hasBestOaLocation W28954040771 @default.
• W2895404077 hasConcept C126201875 @default.
• W2895404077 hasConcept C136229726 @default.
• W2895404077 hasConcept C141071460 @default.
• W2895404077 hasConcept C150903083 @default.
• W2895404077 hasConcept C171250308 @default.
• W2895404077 hasConcept C182606246 @default.
• W2895404077 hasConcept C192562407 @default.
• W2895404077 hasConcept C207001950 @default.
• W2895404077 hasConcept C2776694085 @default.
• W2895404077 hasConcept C2776999253 @default.
• W2895404077 hasConcept C2779820397 @default.
• W2895404077 hasConcept C2781303535 @default.
• W2895404077 hasConcept C502942594 @default.
• W2895404077 hasConcept C509974204 @default.
• W2895404077 hasConcept C71924100 @default.
• W2895404077 hasConcept C86803240 @default.
• W2895404077 hasConcept C92880739 @default.
• W2895404077 hasConcept C98274493 @default.
• W2895404077 hasConceptScore W2895404077C126201875 @default.

• next