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- W2895469056 abstract "Abstract Denitrogenative ortho ‐arylation, vinylation and methylation of 1,2,3‐benzotriazin‐4‐(3 H )‐ones with organic boronic acids catalyzed by nickel complexes to give a wide range of o‐ substituted benzamides were demonstrated. Further, the catalytic reaction is successfully applied to the synthesis of the popular hypertensive drugs losartan and irbesartan in high yields. magnified image" @default.
- W2895469056 created "2018-10-12" @default.
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- W2895469056 date "2018-10-30" @default.
- W2895469056 modified "2023-10-16" @default.
- W2895469056 title "Nickel-Catalyzed Denitrogenative<i>ortho</i>-Arylation of Benzotriazinones with Organic Boronic Acids: an Efficient Route to Losartan and Irbesartan Drug Molecules" @default.
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- W2895469056 doi "https://doi.org/10.1002/adsc.201800923" @default.
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