Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895501620> ?p ?o ?g. }
- W2895501620 endingPage "260" @default.
- W2895501620 startingPage "248" @default.
- W2895501620 abstract "Gold nanoparticles (AuNPs) are found in a wide range of applications and therefore expected to present increasing levels in the environment. There is however limited knowledge concerning the potential toxicity of AuNPs as well as their combined effects with other pollutants. Hence, the present study aimed to investigate the effects of AuNPs alone and combined with the pharmaceutical gemfibrozil (GEM) on different biological responses (behaviour, neurotransmission, biotransformation and oxidative stress) in one of the most consumed fish in southern Europe, the seabream Sparus aurata. Fish were exposed for 96 h to waterborne 40 nm AuNPs with two coatings – citrate and polyvinylpyrrolidone (PVP), alone or combined with GEM. Antioxidant defences were induced in liver and gills upon both AuNPs exposure. Decreased swimming performance (1600 μg.L−1) and oxidative damage in gills (4 and 80 μg.L−1) were observed following exposure to polyvinylpyrrolidone coated gold nanoparticles (PVP-AuNPs). Generally, accumulation of gold in fish tissues and deleterious effects in S. aurata were higher for PVP-AuNPs than for cAuNPs exposures. Although AuNPs and GEM combined effects in gills were generally low, in liver, they were higher than the predicted. The accumulation and effects of AuNPs showed to be dependent on the size, coating, surface charge and aggregation/agglomeration state of nanoparticles. Additionally, it was tissue' specific and dependent on the presence of other contaminants. Although, gold intake by humans is expected to not exceed the estimated tolerable daily intake, it is highly recommended to keep it on track due to the increasing use of AuNPs." @default.
- W2895501620 created "2018-10-12" @default.
- W2895501620 creator A5000511117 @default.
- W2895501620 creator A5001451049 @default.
- W2895501620 creator A5012763805 @default.
- W2895501620 creator A5012851012 @default.
- W2895501620 creator A5013971426 @default.
- W2895501620 creator A5014683731 @default.
- W2895501620 creator A5023864925 @default.
- W2895501620 creator A5056532943 @default.
- W2895501620 creator A5062628386 @default.
- W2895501620 creator A5062703001 @default.
- W2895501620 creator A5067511868 @default.
- W2895501620 creator A5082674998 @default.
- W2895501620 date "2019-01-01" @default.
- W2895501620 modified "2023-10-18" @default.
- W2895501620 title "Effects and bioaccumulation of gold nanoparticles in the gilthead seabream (Sparus aurata) – Single and combined exposures with gemfibrozil" @default.
- W2895501620 cites W1506061303 @default.
- W2895501620 cites W1545899030 @default.
- W2895501620 cites W1581414347 @default.
- W2895501620 cites W1608114173 @default.
- W2895501620 cites W1626021541 @default.
- W2895501620 cites W1739112200 @default.
- W2895501620 cites W1949636578 @default.
- W2895501620 cites W1971048984 @default.
- W2895501620 cites W1971542037 @default.
- W2895501620 cites W1971926466 @default.
- W2895501620 cites W197228448 @default.
- W2895501620 cites W1973681903 @default.
- W2895501620 cites W1977563721 @default.
- W2895501620 cites W1979380803 @default.
- W2895501620 cites W1983310681 @default.
- W2895501620 cites W1985410598 @default.
- W2895501620 cites W1989488807 @default.
- W2895501620 cites W1996642550 @default.
- W2895501620 cites W1996697333 @default.
- W2895501620 cites W2002701398 @default.
- W2895501620 cites W2006757624 @default.
- W2895501620 cites W2007108968 @default.
- W2895501620 cites W2010064606 @default.
- W2895501620 cites W2016774366 @default.
- W2895501620 cites W2019038259 @default.
- W2895501620 cites W2030516579 @default.
- W2895501620 cites W2031983314 @default.
- W2895501620 cites W2032838523 @default.
- W2895501620 cites W2033146579 @default.
- W2895501620 cites W2034286175 @default.
- W2895501620 cites W2035274454 @default.
- W2895501620 cites W2037715171 @default.
- W2895501620 cites W2038261778 @default.
- W2895501620 cites W2040999064 @default.
- W2895501620 cites W2044061165 @default.
- W2895501620 cites W2044794349 @default.
- W2895501620 cites W2046109812 @default.
- W2895501620 cites W2047939851 @default.
- W2895501620 cites W2051168680 @default.
- W2895501620 cites W2056008081 @default.
- W2895501620 cites W2057896087 @default.
- W2895501620 cites W2063576996 @default.
- W2895501620 cites W2065076368 @default.
- W2895501620 cites W2065379666 @default.
- W2895501620 cites W2068932039 @default.
- W2895501620 cites W2069045389 @default.
- W2895501620 cites W2069085012 @default.
- W2895501620 cites W2072418253 @default.
- W2895501620 cites W2072755860 @default.
- W2895501620 cites W2074313296 @default.
- W2895501620 cites W2076442468 @default.
- W2895501620 cites W2078802161 @default.
- W2895501620 cites W2079377329 @default.
- W2895501620 cites W2080466260 @default.
- W2895501620 cites W2081351223 @default.
- W2895501620 cites W2082857620 @default.
- W2895501620 cites W2084089905 @default.
- W2895501620 cites W2087350143 @default.
- W2895501620 cites W2089972286 @default.
- W2895501620 cites W2089982328 @default.
- W2895501620 cites W2103233551 @default.
- W2895501620 cites W2105234505 @default.
- W2895501620 cites W2106412044 @default.
- W2895501620 cites W2114176685 @default.
- W2895501620 cites W2114882618 @default.
- W2895501620 cites W2115029038 @default.
- W2895501620 cites W2116384075 @default.
- W2895501620 cites W2122515160 @default.
- W2895501620 cites W2126519286 @default.
- W2895501620 cites W2133897843 @default.
- W2895501620 cites W2139902021 @default.
- W2895501620 cites W2143588611 @default.
- W2895501620 cites W2145937475 @default.
- W2895501620 cites W2149178439 @default.
- W2895501620 cites W2153832339 @default.
- W2895501620 cites W2154562465 @default.
- W2895501620 cites W2158494199 @default.
- W2895501620 cites W2166885584 @default.
- W2895501620 cites W2167510934 @default.
- W2895501620 cites W2171113588 @default.
- W2895501620 cites W2171420246 @default.