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• W2895511134 endingPage "1409" @default.
• W2895511134 startingPage "1403" @default.
• W2895511134 abstract "Studies have shown that supplementing probiotics in a nasal spray can provide prophylaxis against upper respiratory tract infections. Previously, we found that spraying with Bacillusreduced the concentration of atmospheric ammonia and airborne microbiological aerosols in broiler houses. In the present study, we evaluated the effects of spraying with Bacillus amyloliquefacienson the respiratory mucosal barrier in broilers. Two Trials were conducted simultaneously in four environmentally controlled chambers. In each trail, 320 1-d-old male broilers were randomly assigned to control (CON) and B. amyloliquefaciens(BAQ) group. Eight cages containing 20 birds per cage were placed in two chambers. The BAQ group chambers were sprayed with B. amyloliquefaciensat 4 × 109CFU/m2each day for 42 d. Spraying with B. amyloliquefaciensincreased average daily gain and average daily feed intake in broilers (P< 0.01), but had no effects on FCR (P> 0.05). The relative weights of the bursa (21 d) and spleen (42 d) were higher in the BAQ group (P< 0.05). The serum IgG, IgM (21 d), and IgA, Ig M (42 d) levels were improved in BAQ group (P< 0.05). The sIgA levels in tracheal lavage fluid were significantly higher in the BAQ group than the CON group (P< 0.05). Furthermore, treatment with BAQ downregulated IL-6 and IFN-γ (P< 0.05), but upregulated IL-2, occludin, and mucin-2 (P< 0.05). In addition, the number of acidic goblet cells was significantly higher in the tracheas of treated broilers than untreated broilers (P< 0.05). In conclusion, spraying with B. amyloliquefaciens may help to enhance the growth performance and improve the respiratory mucosal barrier in broiler chickens." @default.
• W2895511134 created "2018-10-12" @default.
• W2895511134 creator A5035549083 @default.
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• W2895511134 date "2019-03-01" @default.
• W2895511134 modified "2023-10-15" @default.
• W2895511134 title "Bacillus amyloliquefaciens spray improves the growth performance, immune status, and respiratory mucosal barrier in broiler chickens" @default.
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• W2895511134 doi "https://doi.org/10.3382/ps/pey478" @default.
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