Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895522499> ?p ?o ?g. }
- W2895522499 endingPage "10240" @default.
- W2895522499 startingPage "10234" @default.
- W2895522499 abstract "The development of (4 + 3) cyclizations of vinyl aziridines, especially catalytic asymmetric versions, is needed in organic synthesis. This report describes an iridium-catalyzed (4 + 3) cyclization of vinyl aziridines with para-quinone methide (p-QM) derivatives, and this reaction constructs a seven-membered benzoxazepine scaffold in moderate to high yields (40% to 96%) and considerable diastereoselectivities (70:30 dr to >95:5 dr). Moreover, the catalytic asymmetric version of this (4 + 3) cyclization is accomplished in the presence of a palladium catalyst and a chiral ligand, and this modification provides chiral benzoxazepine derivatives in generally moderate diastereoselectivities (73:27 dr to 91:9 dr) and high enantioselectivities (92:8 to 96:4 er). This approach delivers a scarcely reported catalytic enantioselective (4 + 3) cyclization of vinyl aziridines and offers a metal-catalyzed (4 + 3) cyclization of p-QM derivatives." @default.
- W2895522499 created "2018-10-12" @default.
- W2895522499 creator A5027077267 @default.
- W2895522499 creator A5036274809 @default.
- W2895522499 creator A5057027283 @default.
- W2895522499 creator A5070370130 @default.
- W2895522499 creator A5086163138 @default.
- W2895522499 date "2018-10-03" @default.
- W2895522499 modified "2023-10-15" @default.
- W2895522499 title "Metal-Catalyzed (4 + 3) Cyclization of Vinyl Aziridines with <i>para</i>-Quinone Methide Derivatives" @default.
- W2895522499 cites W1594669205 @default.
- W2895522499 cites W1964579733 @default.
- W2895522499 cites W1967663014 @default.
- W2895522499 cites W2019325392 @default.
- W2895522499 cites W2025823525 @default.
- W2895522499 cites W2053530690 @default.
- W2895522499 cites W2055564123 @default.
- W2895522499 cites W2073422424 @default.
- W2895522499 cites W2082415360 @default.
- W2895522499 cites W2092309173 @default.
- W2895522499 cites W2097520612 @default.
- W2895522499 cites W2107044826 @default.
- W2895522499 cites W2115049190 @default.
- W2895522499 cites W2122735191 @default.
- W2895522499 cites W2140072993 @default.
- W2895522499 cites W2140088732 @default.
- W2895522499 cites W2143863526 @default.
- W2895522499 cites W2145147308 @default.
- W2895522499 cites W2156682732 @default.
- W2895522499 cites W2160281323 @default.
- W2895522499 cites W2232751126 @default.
- W2895522499 cites W2260924952 @default.
- W2895522499 cites W2260998514 @default.
- W2895522499 cites W2276908835 @default.
- W2895522499 cites W2320853506 @default.
- W2895522499 cites W2330349851 @default.
- W2895522499 cites W2335500056 @default.
- W2895522499 cites W2378704410 @default.
- W2895522499 cites W240973036 @default.
- W2895522499 cites W2462922148 @default.
- W2895522499 cites W2463331683 @default.
- W2895522499 cites W2467699847 @default.
- W2895522499 cites W2496994150 @default.
- W2895522499 cites W2513058735 @default.
- W2895522499 cites W2514331167 @default.
- W2895522499 cites W2514502533 @default.
- W2895522499 cites W2548894381 @default.
- W2895522499 cites W2553202693 @default.
- W2895522499 cites W2561999500 @default.
- W2895522499 cites W2562132301 @default.
- W2895522499 cites W2586920840 @default.
- W2895522499 cites W2599899755 @default.
- W2895522499 cites W2602123043 @default.
- W2895522499 cites W2604523339 @default.
- W2895522499 cites W2728867461 @default.
- W2895522499 cites W2734513052 @default.
- W2895522499 cites W2743538667 @default.
- W2895522499 cites W2759366028 @default.
- W2895522499 cites W2767428890 @default.
- W2895522499 cites W2768526259 @default.
- W2895522499 cites W2775060101 @default.
- W2895522499 cites W2782871138 @default.
- W2895522499 cites W2785024371 @default.
- W2895522499 cites W2786593092 @default.
- W2895522499 cites W2786910425 @default.
- W2895522499 cites W2787931870 @default.
- W2895522499 cites W2792923503 @default.
- W2895522499 cites W2800458446 @default.
- W2895522499 cites W2804733860 @default.
- W2895522499 cites W2805511426 @default.
- W2895522499 cites W4248757943 @default.
- W2895522499 doi "https://doi.org/10.1021/acscatal.8b03410" @default.
- W2895522499 hasPublicationYear "2018" @default.
- W2895522499 type Work @default.
- W2895522499 sameAs 2895522499 @default.
- W2895522499 citedByCount "111" @default.
- W2895522499 countsByYear W28955224992018 @default.
- W2895522499 countsByYear W28955224992019 @default.
- W2895522499 countsByYear W28955224992020 @default.
- W2895522499 countsByYear W28955224992021 @default.
- W2895522499 countsByYear W28955224992022 @default.
- W2895522499 countsByYear W28955224992023 @default.
- W2895522499 crossrefType "journal-article" @default.
- W2895522499 hasAuthorship W2895522499A5027077267 @default.
- W2895522499 hasAuthorship W2895522499A5036274809 @default.
- W2895522499 hasAuthorship W2895522499A5057027283 @default.
- W2895522499 hasAuthorship W2895522499A5070370130 @default.
- W2895522499 hasAuthorship W2895522499A5086163138 @default.
- W2895522499 hasConcept C116569031 @default.
- W2895522499 hasConcept C146686406 @default.
- W2895522499 hasConcept C161790260 @default.
- W2895522499 hasConcept C170493617 @default.
- W2895522499 hasConcept C178790620 @default.
- W2895522499 hasConcept C185592680 @default.
- W2895522499 hasConcept C21951064 @default.
- W2895522499 hasConcept C502130503 @default.
- W2895522499 hasConcept C528581852 @default.
- W2895522499 hasConcept C544153396 @default.