Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895527090> ?p ?o ?g. }
- W2895527090 endingPage "1580" @default.
- W2895527090 startingPage "1574" @default.
- W2895527090 abstract "Raman spectroscopy offers an attractive platform for real‐time monitoring and control of metabolites and feeds in cell culture processes, including mammalian cell culture for biopharmaceutical production. However, specific cell culture processes may generate substantial concentrations of chemical species and byproducts with high levels of autofluorescence when excited with the standard 785 nm wavelength. Shifting excitation further toward the near‐infrared allows reduction or elimination of process autofluorescence. We demonstrate such a reduction in a highly autofluorescent mammalian cell culture process. Using the Kaiser RXN2–1000 platform, which utilizes excitation at 993 nm, we developed multivariate glucose models in a cell culture process which was previously impossible using 785 nm excitation. Additionally, the glucose level in the production bioreactor was controlled entirely by Raman adaptive feeding, allowing for maintenance of glucose levels at an arbitrary set point for the duration of the culture. © 2018 American Institute of Chemical Engineers Biotechnol. Prog ., 34:1574–1580, 2018" @default.
- W2895527090 created "2018-10-12" @default.
- W2895527090 creator A5006442093 @default.
- W2895527090 creator A5028889544 @default.
- W2895527090 creator A5030409674 @default.
- W2895527090 creator A5059259138 @default.
- W2895527090 creator A5059609760 @default.
- W2895527090 creator A5077314703 @default.
- W2895527090 creator A5089189548 @default.
- W2895527090 date "2018-10-03" @default.
- W2895527090 modified "2023-10-12" @default.
- W2895527090 title "Glucose monitoring and adaptive feeding of mammalian cell culture in the presence of strong autofluorescence by near infrared Raman spectroscopy" @default.
- W2895527090 cites W1750907832 @default.
- W2895527090 cites W1973888845 @default.
- W2895527090 cites W1987191121 @default.
- W2895527090 cites W2006947259 @default.
- W2895527090 cites W2021199190 @default.
- W2895527090 cites W2029878671 @default.
- W2895527090 cites W2030678467 @default.
- W2895527090 cites W2044366780 @default.
- W2895527090 cites W2057328981 @default.
- W2895527090 cites W2073927666 @default.
- W2895527090 cites W2168931684 @default.
- W2895527090 cites W2179091795 @default.
- W2895527090 cites W2399070630 @default.
- W2895527090 cites W2515226110 @default.
- W2895527090 cites W2783157746 @default.
- W2895527090 cites W3123379167 @default.
- W2895527090 doi "https://doi.org/10.1002/btpr.2711" @default.
- W2895527090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30281947" @default.
- W2895527090 hasPublicationYear "2018" @default.
- W2895527090 type Work @default.
- W2895527090 sameAs 2895527090 @default.
- W2895527090 citedByCount "23" @default.
- W2895527090 countsByYear W28955270902019 @default.
- W2895527090 countsByYear W28955270902020 @default.
- W2895527090 countsByYear W28955270902021 @default.
- W2895527090 countsByYear W28955270902022 @default.
- W2895527090 countsByYear W28955270902023 @default.
- W2895527090 crossrefType "journal-article" @default.
- W2895527090 hasAuthorship W2895527090A5006442093 @default.
- W2895527090 hasAuthorship W2895527090A5028889544 @default.
- W2895527090 hasAuthorship W2895527090A5030409674 @default.
- W2895527090 hasAuthorship W2895527090A5059259138 @default.
- W2895527090 hasAuthorship W2895527090A5059609760 @default.
- W2895527090 hasAuthorship W2895527090A5077314703 @default.
- W2895527090 hasAuthorship W2895527090A5089189548 @default.
- W2895527090 hasConcept C113196181 @default.
- W2895527090 hasConcept C120665830 @default.
- W2895527090 hasConcept C121332964 @default.
- W2895527090 hasConcept C12554922 @default.
- W2895527090 hasConcept C1491633281 @default.
- W2895527090 hasConcept C158355884 @default.
- W2895527090 hasConcept C168170006 @default.
- W2895527090 hasConcept C178790620 @default.
- W2895527090 hasConcept C179687394 @default.
- W2895527090 hasConcept C185592680 @default.
- W2895527090 hasConcept C192562407 @default.
- W2895527090 hasConcept C31332276 @default.
- W2895527090 hasConcept C32891209 @default.
- W2895527090 hasConcept C40003534 @default.
- W2895527090 hasConcept C43571822 @default.
- W2895527090 hasConcept C43617362 @default.
- W2895527090 hasConcept C54355233 @default.
- W2895527090 hasConcept C55493867 @default.
- W2895527090 hasConcept C62520636 @default.
- W2895527090 hasConcept C81885089 @default.
- W2895527090 hasConcept C86803240 @default.
- W2895527090 hasConcept C91881484 @default.
- W2895527090 hasConceptScore W2895527090C113196181 @default.
- W2895527090 hasConceptScore W2895527090C120665830 @default.
- W2895527090 hasConceptScore W2895527090C121332964 @default.
- W2895527090 hasConceptScore W2895527090C12554922 @default.
- W2895527090 hasConceptScore W2895527090C1491633281 @default.
- W2895527090 hasConceptScore W2895527090C158355884 @default.
- W2895527090 hasConceptScore W2895527090C168170006 @default.
- W2895527090 hasConceptScore W2895527090C178790620 @default.
- W2895527090 hasConceptScore W2895527090C179687394 @default.
- W2895527090 hasConceptScore W2895527090C185592680 @default.
- W2895527090 hasConceptScore W2895527090C192562407 @default.
- W2895527090 hasConceptScore W2895527090C31332276 @default.
- W2895527090 hasConceptScore W2895527090C32891209 @default.
- W2895527090 hasConceptScore W2895527090C40003534 @default.
- W2895527090 hasConceptScore W2895527090C43571822 @default.
- W2895527090 hasConceptScore W2895527090C43617362 @default.
- W2895527090 hasConceptScore W2895527090C54355233 @default.
- W2895527090 hasConceptScore W2895527090C55493867 @default.
- W2895527090 hasConceptScore W2895527090C62520636 @default.
- W2895527090 hasConceptScore W2895527090C81885089 @default.
- W2895527090 hasConceptScore W2895527090C86803240 @default.
- W2895527090 hasConceptScore W2895527090C91881484 @default.
- W2895527090 hasIssue "6" @default.
- W2895527090 hasLocation W28955270901 @default.
- W2895527090 hasLocation W28955270902 @default.
- W2895527090 hasOpenAccess W2895527090 @default.
- W2895527090 hasPrimaryLocation W28955270901 @default.
- W2895527090 hasRelatedWork W1982369016 @default.
- W2895527090 hasRelatedWork W2002347108 @default.