FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895533361> ?p ?o ?g. }

• W2895533361 abstract "Abstract Observational studies have identified surgical factors that are associated with a reduced risk of mortality after joint replacement. It is not clear whether these are causal or reflect patient selection. Data on the first primary hip (n = 424,156) and knee replacements (n = 469,989) performed for osteoarthritis in the National Joint Registry were analysed. Flexible parametric survival modelling was used to determine if risk factors for mortality in the perioperative period persisted. To explore selection bias, standardised mortality ratios were calculated for all-cause, respiratory and smoking related cancer mortality using population rates. Selection was apparent for hip resurfacing, combined spinal and general anaesthetic and unicondylar knee implants; reduced mortality was observed for many years for both all and other causes of mortality with a waning effect. Mechanical thromboprophylaxis was also suggestive of selection although patients receiving aspirin had sustained reduced mortality, possibly due to to a cardioprotective effect. Posterior approach for hips was ambiguous with a possible causal component. Spinal anaesthesia was suggestive of a causal effect. We are reliant on observational data when it is not feasible to undertake randomised trials. Our approach of looking at long term mortality risks for perioperative interventions provides further insights to differentiate causal interventions from selection. We recommend the use of aspirin chemothromboprophylaxis, the posterior approach and spinal anaesthetic in total hip replacement due to the apparent causal effect on reduced mortality." @default.
• W2895533361 created "2018-10-12" @default.
• W2895533361 creator A5003846428 @default.
• W2895533361 creator A5071306973 @default.
• W2895533361 creator A5072210649 @default.
• W2895533361 creator A5072895418 @default.
• W2895533361 creator A5076039186 @default.
• W2895533361 date "2018-10-09" @default.
• W2895533361 modified "2023-09-25" @default.
• W2895533361 title "Using long term mortality to determine which perioperative risk factors of mortality following hip and knee replacement may be causal" @default.
• W2895533361 cites W1480729244 @default.
• W2895533361 cites W1978185279 @default.
• W2895533361 cites W1993873451 @default.
• W2895533361 cites W1994482675 @default.
• W2895533361 cites W2000445173 @default.
• W2895533361 cites W2005426927 @default.
• W2895533361 cites W2024352468 @default.
• W2895533361 cites W2061326496 @default.
• W2895533361 cites W2084995544 @default.
• W2895533361 cites W2114788387 @default.
• W2895533361 cites W2125404215 @default.
• W2895533361 cites W2135369095 @default.
• W2895533361 cites W2138771533 @default.
• W2895533361 cites W2152785980 @default.
• W2895533361 cites W2169705708 @default.
• W2895533361 cites W2253964039 @default.
• W2895533361 cites W2302319728 @default.
• W2895533361 cites W2307912464 @default.
• W2895533361 cites W2367710406 @default.
• W2895533361 cites W2567606864 @default.
• W2895533361 cites W2616131010 @default.
• W2895533361 cites W2988641574 @default.
• W2895533361 cites W4239471829 @default.
• W2895533361 cites W4290747706 @default.
• W2895533361 doi "https://doi.org/10.1038/s41598-018-33314-0" @default.
• W2895533361 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6177450" @default.
• W2895533361 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30302017" @default.
• W2895533361 hasPublicationYear "2018" @default.
• W2895533361 type Work @default.
• W2895533361 sameAs 2895533361 @default.
• W2895533361 citedByCount "10" @default.
• W2895533361 countsByYear W28955333612019 @default.
• W2895533361 countsByYear W28955333612020 @default.
• W2895533361 countsByYear W28955333612021 @default.
• W2895533361 countsByYear W28955333612022 @default.
• W2895533361 crossrefType "journal-article" @default.
• W2895533361 hasAuthorship W2895533361A5003846428 @default.
• W2895533361 hasAuthorship W2895533361A5071306973 @default.
• W2895533361 hasAuthorship W2895533361A5072210649 @default.
• W2895533361 hasAuthorship W2895533361A5072895418 @default.
• W2895533361 hasAuthorship W2895533361A5076039186 @default.
• W2895533361 hasBestOaLocation W28955333611 @default.
• W2895533361 hasConcept C126322002 @default.
• W2895533361 hasConcept C141071460 @default.
• W2895533361 hasConcept C142724271 @default.
• W2895533361 hasConcept C177713679 @default.
• W2895533361 hasConcept C179755657 @default.
• W2895533361 hasConcept C204787440 @default.
• W2895533361 hasConcept C23131810 @default.
• W2895533361 hasConcept C2776164576 @default.
• W2895533361 hasConcept C2777417762 @default.
• W2895533361 hasConcept C2777628954 @default.
• W2895533361 hasConcept C2778104916 @default.
• W2895533361 hasConcept C2778336525 @default.
• W2895533361 hasConcept C2908647359 @default.
• W2895533361 hasConcept C3018792137 @default.
• W2895533361 hasConcept C31174226 @default.
• W2895533361 hasConcept C71924100 @default.
• W2895533361 hasConcept C99454951 @default.
• W2895533361 hasConceptScore W2895533361C126322002 @default.
• W2895533361 hasConceptScore W2895533361C141071460 @default.
• W2895533361 hasConceptScore W2895533361C142724271 @default.
• W2895533361 hasConceptScore W2895533361C177713679 @default.
• W2895533361 hasConceptScore W2895533361C179755657 @default.
• W2895533361 hasConceptScore W2895533361C204787440 @default.
• W2895533361 hasConceptScore W2895533361C23131810 @default.
• W2895533361 hasConceptScore W2895533361C2776164576 @default.
• W2895533361 hasConceptScore W2895533361C2777417762 @default.
• W2895533361 hasConceptScore W2895533361C2777628954 @default.
• W2895533361 hasConceptScore W2895533361C2778104916 @default.
• W2895533361 hasConceptScore W2895533361C2778336525 @default.
• W2895533361 hasConceptScore W2895533361C2908647359 @default.
• W2895533361 hasConceptScore W2895533361C3018792137 @default.
• W2895533361 hasConceptScore W2895533361C31174226 @default.
• W2895533361 hasConceptScore W2895533361C71924100 @default.
• W2895533361 hasConceptScore W2895533361C99454951 @default.
• W2895533361 hasIssue "1" @default.
• W2895533361 hasLocation W28955333611 @default.
• W2895533361 hasLocation W28955333612 @default.
• W2895533361 hasLocation W28955333613 @default.
• W2895533361 hasLocation W28955333614 @default.
• W2895533361 hasLocation W28955333615 @default.
• W2895533361 hasOpenAccess W2895533361 @default.
• W2895533361 hasPrimaryLocation W28955333611 @default.
• W2895533361 hasRelatedWork W2054856593 @default.
• W2895533361 hasRelatedWork W2081380118 @default.
• W2895533361 hasRelatedWork W2115095217 @default.
• W2895533361 hasRelatedWork W2402197575 @default.
• W2895533361 hasRelatedWork W2613064683 @default.
• W2895533361 hasRelatedWork W2953217707 @default.

• next