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• W2895535090 abstract "Background Numerous studies have suggested that quantitative susceptibility mapping (QSM) and transverse relaxation rates ( ) are useful to monitor neurological diseases. For clinical use of QSM and , reproducibility is an important feature. However, respiration‐induced local magnetic field variation makes artifacts in gradient echo‐based images and reduces the reproducibility of QSM and . Purpose To investigate the improvement of reproducibility of QSM and after the correction of respiration‐induced field variation, and to assess the effect of varying types of the region of interest (ROI) analysis on reproducibility. Study Type Reproducibility study. Population Ten controls. Field Strength/Sequence 3T/multiecho gradient echo sequence. Assessment Intrascan reproducibility of QSM and was investigated in ROIs before and after the respiration correction. Statistical Tests Reproducibility was obtained by the square of voxel‐wise correlation coefficients between scans. A paired t ‐test was performed for comparison between before and after the respiration correction and between QSM and . Results Based on the ROI analysis, reproducibility increased after the respiration correction. Reproducibility in the white matter (11.89% increased in QSM and 23.38% in , P = 0.009 and 0.024, respectively) and deep gray matter (5.50% increased in QSM and 13.96% in , P = 0.024 and 0.019, respectively) increased significantly after the respiration correction. Reproducibility of was higher than that of QSM in the whole brain and cortical gray matter, while QSM maps showed higher reproducibility than in the white matter and deep gray matter. Data Conclusion Respiration‐induced error correction significantly improved reproducibility in QSM and mapping. QSM and mapping showed a different level of reproducibility depending on the types of ROI analysis. Level of Evidence: 4 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018." @default.
• W2895535090 created "2018-10-12" @default.
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• W2895535090 date "2018-10-04" @default.
• W2895535090 modified "2023-10-17" @default.
• W2895535090 title "Improvement of reproducibility in quantitative susceptibility mapping (QSM) and transverse relaxation rates () after physiological noise correction" @default.
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• W2895535090 doi "https://doi.org/10.1002/jmri.26522" @default.
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