FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895537614> ?p ?o ?g. }

• W2895537614 endingPage "96" @default.
• W2895537614 startingPage "89" @default.
• W2895537614 abstract "Chitosan (CS), a nature-derived polysaccharide, is a promising nano-carrier material with good biocompatibility and biodegradability. However, the biomedical applications of CS are hindered because of its poor aqueous solubility. To circumvent this drawback, a series of Brij-grafted-chitosan copolymers (BCs) with various grafting degree of Brij-S20 were first developed and reported. The results indicated that the water solubility of BCs (from 9.13 to 9.54 mg/mL) were much higher than that of CS (0.32 mg/mL), due to the broken intra- and/or inter-molecular hydrogen bonds and the decreased initial crystallinity in BCs. The amphiphilic structure of BCs presented lower critical micelle concentration (0.116–0.376 mg/mL) thus facilitating its self-aggregation into micelles for drug encapsulation. Moreover, BCs markedly enhanced the intracellular uptake of rhodamine-123 in MDCK-MDR1 cells. This inhibition on Pgp-mediated efflux was also confirmed by confocal microscopy. In conclusion, BCs could be further developed as polymeric nano-carriers for those drugs with Pgp-mediated efflux." @default.
• W2895537614 created "2018-10-12" @default.
• W2895537614 creator A5003056918 @default.
• W2895537614 creator A5023736282 @default.
• W2895537614 creator A5030600034 @default.
• W2895537614 creator A5041150039 @default.
• W2895537614 creator A5043034094 @default.
• W2895537614 creator A5050209085 @default.
• W2895537614 creator A5052625603 @default.
• W2895537614 creator A5082175651 @default.
• W2895537614 creator A5090434715 @default.
• W2895537614 date "2019-01-01" @default.
• W2895537614 modified "2023-10-01" @default.
• W2895537614 title "Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations" @default.
• W2895537614 cites W1964470226 @default.
• W2895537614 cites W1975392076 @default.
• W2895537614 cites W1979917539 @default.
• W2895537614 cites W1994986226 @default.
• W2895537614 cites W1997154876 @default.
• W2895537614 cites W2002115431 @default.
• W2895537614 cites W2007080192 @default.
• W2895537614 cites W2009914452 @default.
• W2895537614 cites W2014747990 @default.
• W2895537614 cites W2032222317 @default.
• W2895537614 cites W2037192290 @default.
• W2895537614 cites W2037621239 @default.
• W2895537614 cites W2053437387 @default.
• W2895537614 cites W2056096741 @default.
• W2895537614 cites W2056983596 @default.
• W2895537614 cites W2057988233 @default.
• W2895537614 cites W2078877172 @default.
• W2895537614 cites W2086514756 @default.
• W2895537614 cites W2087421919 @default.
• W2895537614 cites W2097154067 @default.
• W2895537614 cites W2118822263 @default.
• W2895537614 cites W2121325790 @default.
• W2895537614 cites W2124131536 @default.
• W2895537614 cites W2125439185 @default.
• W2895537614 cites W2154828915 @default.
• W2895537614 cites W2250347759 @default.
• W2895537614 cites W2258098269 @default.
• W2895537614 cites W2320831021 @default.
• W2895537614 cites W2324431764 @default.
• W2895537614 cites W2324775542 @default.
• W2895537614 cites W2471767856 @default.
• W2895537614 cites W2609615149 @default.
• W2895537614 cites W2626389078 @default.
• W2895537614 cites W2754920172 @default.
• W2895537614 cites W2809920884 @default.
• W2895537614 doi "https://doi.org/10.1016/j.carbpol.2018.10.007" @default.
• W2895537614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30366546" @default.
• W2895537614 hasPublicationYear "2019" @default.
• W2895537614 type Work @default.
• W2895537614 sameAs 2895537614 @default.
• W2895537614 citedByCount "15" @default.
• W2895537614 countsByYear W28955376142019 @default.
• W2895537614 countsByYear W28955376142020 @default.
• W2895537614 countsByYear W28955376142021 @default.
• W2895537614 countsByYear W28955376142022 @default.
• W2895537614 countsByYear W28955376142023 @default.
• W2895537614 crossrefType "journal-article" @default.
• W2895537614 hasAuthorship W2895537614A5003056918 @default.
• W2895537614 hasAuthorship W2895537614A5023736282 @default.
• W2895537614 hasAuthorship W2895537614A5030600034 @default.
• W2895537614 hasAuthorship W2895537614A5041150039 @default.
• W2895537614 hasAuthorship W2895537614A5043034094 @default.
• W2895537614 hasAuthorship W2895537614A5050209085 @default.
• W2895537614 hasAuthorship W2895537614A5052625603 @default.
• W2895537614 hasAuthorship W2895537614A5082175651 @default.
• W2895537614 hasAuthorship W2895537614A5090434715 @default.
• W2895537614 hasConcept C101335993 @default.
• W2895537614 hasConcept C11268172 @default.
• W2895537614 hasConcept C127413603 @default.
• W2895537614 hasConcept C13245373 @default.
• W2895537614 hasConcept C13965031 @default.
• W2895537614 hasConcept C155574463 @default.
• W2895537614 hasConcept C15920480 @default.
• W2895537614 hasConcept C178790620 @default.
• W2895537614 hasConcept C184651966 @default.
• W2895537614 hasConcept C185592680 @default.
• W2895537614 hasConcept C188027245 @default.
• W2895537614 hasConcept C2777230088 @default.
• W2895537614 hasConcept C2779732960 @default.
• W2895537614 hasConcept C2779820397 @default.
• W2895537614 hasConcept C42360764 @default.
• W2895537614 hasConcept C46275449 @default.
• W2895537614 hasConcept C521977710 @default.
• W2895537614 hasConcept C64237528 @default.
• W2895537614 hasConcept C67407626 @default.
• W2895537614 hasConcept C8010536 @default.
• W2895537614 hasConceptScore W2895537614C101335993 @default.
• W2895537614 hasConceptScore W2895537614C11268172 @default.
• W2895537614 hasConceptScore W2895537614C127413603 @default.
• W2895537614 hasConceptScore W2895537614C13245373 @default.
• W2895537614 hasConceptScore W2895537614C13965031 @default.
• W2895537614 hasConceptScore W2895537614C155574463 @default.
• W2895537614 hasConceptScore W2895537614C15920480 @default.
• W2895537614 hasConceptScore W2895537614C178790620 @default.

• next