Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895540934> ?p ?o ?g. }
- W2895540934 endingPage "63" @default.
- W2895540934 startingPage "49" @default.
- W2895540934 abstract "<b><i>Background:</i></b> Studying the impact of genetic testing interventions on lifestyle behaviour change has been a priority area of research in recent years. Substantial heterogeneity exists in the results and conclusions of this literature, which has yet to be explained using validated behaviour change theory and an assessment of the quality of genetic interventions. The theory of planned behaviour (TPB) helps to explain key contributors to behaviour change. It has been hypothesized that <i>personalization</i> could be added to this theory to help predict changes in health behaviours. <b><i>Purpose:</i></b> This systematic review provides a detailed, comprehensive identification, assessment, and summary of primary research articles pertaining to lifestyle behaviour change (nutrition, physical activity, sleep, and smoking) resulting from genetic testing interventions. The present review further aims to provide in-depth analyses of studies conducted to date within the context of the TPB and the quality of genetic interventions provided to participants while aiming to determine whether or not genetic testing facilitates changes in lifestyle habits. This review is timely in light of a recently published “call-to-action” paper, highlighting the need to incorporate the TPB into personalized healthcare behaviour change research. <b><i>Methods:</i></b> Three bibliographic databases, one key website, and article reference lists were searched for relevant primary research articles. The PRISMA Flow Diagram and PRISMA Checklist were used to guide the search strategy and manuscript preparation. Out of 32,783 titles retrieved, 26 studies met the inclusion criteria. Three quality assessments were conducted and included: (1) risk of bias, (2) quality of genetic interventions, and (3) consideration of theoretical underpinnings – primarily the TPB. <b><i>Results:</i></b> Risk of bias in studies was overall rated to be “fair.” Consideration of the TPB was “poor,” with no study making reference to this validated theory. While some studies (<i>n</i> = 11; 42%) made reference to other behaviour change theories, these theories were generally mentioned briefly, and were not thoroughly incorporated into the study design or analyses. The genetic interventions provided to participants were overall of “poor” quality. However, a separate analysis of studies using controlled intervention research methods demonstrated the use of higher-quality genetic interventions (overall rated to be “fair”). The provision of actionable recommendations informed by genetic testing was more likely to facilitate behaviour change than the provision of genetic information without actionable lifestyle recommendations. Several studies of good quality demonstrated changes in lifestyle habits arising from the provision of genetic interventions. The most promising lifestyle changes were changes in nutrition. <b><i>Conclusions:</i></b> It is possible to facilitate behaviour change using genetic testing as the catalyst. Future research should ensure that high-quality genetic interventions are provided to participants, and should consider validated theories such as the TPB in their study design and analyses. Further recommendations for future research are provided." @default.
- W2895540934 created "2018-10-12" @default.
- W2895540934 creator A5007111141 @default.
- W2895540934 creator A5016716846 @default.
- W2895540934 creator A5017315432 @default.
- W2895540934 creator A5019934328 @default.
- W2895540934 creator A5059259910 @default.
- W2895540934 date "2018-01-01" @default.
- W2895540934 modified "2023-10-14" @default.
- W2895540934 title "A Systematic Review of Genetic Testing and Lifestyle Behaviour Change: Are We Using High-Quality Genetic Interventions and Considering Behaviour Change Theory?" @default.
- W2895540934 cites W1549312923 @default.
- W2895540934 cites W1902859384 @default.
- W2895540934 cites W1972508135 @default.
- W2895540934 cites W1975771460 @default.
- W2895540934 cites W1976355719 @default.
- W2895540934 cites W1979221467 @default.
- W2895540934 cites W1979581505 @default.
- W2895540934 cites W1980078249 @default.
- W2895540934 cites W1981476403 @default.
- W2895540934 cites W1987178383 @default.
- W2895540934 cites W1989072690 @default.
- W2895540934 cites W1989879035 @default.
- W2895540934 cites W1997390555 @default.
- W2895540934 cites W2004109309 @default.
- W2895540934 cites W2007817238 @default.
- W2895540934 cites W2024006092 @default.
- W2895540934 cites W2041615463 @default.
- W2895540934 cites W2050455383 @default.
- W2895540934 cites W2054128321 @default.
- W2895540934 cites W2054610007 @default.
- W2895540934 cites W2067404301 @default.
- W2895540934 cites W2069499175 @default.
- W2895540934 cites W2073532670 @default.
- W2895540934 cites W2075059741 @default.
- W2895540934 cites W2087689337 @default.
- W2895540934 cites W2093551683 @default.
- W2895540934 cites W2099697766 @default.
- W2895540934 cites W2116181900 @default.
- W2895540934 cites W2118276768 @default.
- W2895540934 cites W2120118206 @default.
- W2895540934 cites W2122561085 @default.
- W2895540934 cites W2131500117 @default.
- W2895540934 cites W2132470305 @default.
- W2895540934 cites W2140969549 @default.
- W2895540934 cites W2141687508 @default.
- W2895540934 cites W2142912849 @default.
- W2895540934 cites W2149278098 @default.
- W2895540934 cites W2152095411 @default.
- W2895540934 cites W2153483268 @default.
- W2895540934 cites W2158822657 @default.
- W2895540934 cites W2169816221 @default.
- W2895540934 cites W2270835494 @default.
- W2895540934 cites W2299533639 @default.
- W2895540934 cites W2387702243 @default.
- W2895540934 cites W2470544577 @default.
- W2895540934 cites W2579226296 @default.
- W2895540934 cites W2592900884 @default.
- W2895540934 cites W2596170870 @default.
- W2895540934 cites W2597054569 @default.
- W2895540934 cites W2614578122 @default.
- W2895540934 cites W2616414475 @default.
- W2895540934 cites W2619282411 @default.
- W2895540934 cites W2768705105 @default.
- W2895540934 cites W4294215472 @default.
- W2895540934 doi "https://doi.org/10.1159/000488086" @default.
- W2895540934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29635250" @default.
- W2895540934 hasPublicationYear "2018" @default.
- W2895540934 type Work @default.
- W2895540934 sameAs 2895540934 @default.
- W2895540934 citedByCount "62" @default.
- W2895540934 countsByYear W28955409342018 @default.
- W2895540934 countsByYear W28955409342019 @default.
- W2895540934 countsByYear W28955409342020 @default.
- W2895540934 countsByYear W28955409342021 @default.
- W2895540934 countsByYear W28955409342022 @default.
- W2895540934 countsByYear W28955409342023 @default.
- W2895540934 crossrefType "journal-article" @default.
- W2895540934 hasAuthorship W2895540934A5007111141 @default.
- W2895540934 hasAuthorship W2895540934A5016716846 @default.
- W2895540934 hasAuthorship W2895540934A5017315432 @default.
- W2895540934 hasAuthorship W2895540934A5019934328 @default.
- W2895540934 hasAuthorship W2895540934A5059259910 @default.
- W2895540934 hasBestOaLocation W28955409341 @default.
- W2895540934 hasConcept C118552586 @default.
- W2895540934 hasConcept C14262774 @default.
- W2895540934 hasConcept C151730666 @default.
- W2895540934 hasConcept C154945302 @default.
- W2895540934 hasConcept C15744967 @default.
- W2895540934 hasConcept C180747234 @default.
- W2895540934 hasConcept C189708586 @default.
- W2895540934 hasConcept C27415008 @default.
- W2895540934 hasConcept C2775924081 @default.
- W2895540934 hasConcept C2779343474 @default.
- W2895540934 hasConcept C2779356329 @default.
- W2895540934 hasConcept C2779473830 @default.
- W2895540934 hasConcept C3020759390 @default.
- W2895540934 hasConcept C41008148 @default.
- W2895540934 hasConcept C55493867 @default.