Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895547776> ?p ?o ?g. }
- W2895547776 endingPage "e12463" @default.
- W2895547776 startingPage "e12463" @default.
- W2895547776 abstract "Vitamin D maintains calcium balance and has immunomodulatory effects. Only few studies have revealed the relationship between vitamin D and its associated factors in Mycobacterium avium complex (MAC) infection. This study aimed to investigate the effects of MAC infection on serum vitamin D, human cationic antimicrobial protein 18, its C-terminal 37 amino acid fragment (hCAP18/LL-37) levels, and bone mineral density (BMD).We enrolled 58 patients with MAC lung disease and 15 control participants. Serum 25-hydroxyvitamin D and hCAP18/LL-37 levels were measured via enzyme-linked immunosorbent assay. Lastly, computed tomography scan density readings of the BMD of the thoracic and lumbar vertebral bones (Th4, Th7, Th10, and L1) were assessed.No significant differences in patient characteristics and serum vitamin D levels were observed. Patients with MAC lung disease had significantly low serum hCAP18/LL-37 levels (P = .049). Moreover, low BMD of the mean thoracic and lumbar vertebrae was observed (mean Th, P = .012; L1, P = .48, respectively). A higher prevalence of scoliosis (P = .031) was observed in the participants with low BMD compared with the control participants. Based on a multivariate analysis, patients with MAC lung disease had significantly lower body mass index [odds ratio (OR), 19.1; 95% confidence interval (CI), 2.0-419.0; P < .01] and vertebral BMD (OR, 12.4; 95% CI, 1.7-160.6; P = .012) than control participants.Serum hCAP18/LL-37 level and BMD were significantly decreased in patients with MAC lung disease without relation to serum vitamin D level. The vitamin D-independent pathway might affect the waning of antimicrobial peptides and decrease in BMD." @default.
- W2895547776 created "2018-10-12" @default.
- W2895547776 creator A5048538074 @default.
- W2895547776 creator A5050972585 @default.
- W2895547776 creator A5054170761 @default.
- W2895547776 creator A5062985377 @default.
- W2895547776 creator A5069366555 @default.
- W2895547776 creator A5084313756 @default.
- W2895547776 date "2018-09-01" @default.
- W2895547776 modified "2023-10-18" @default.
- W2895547776 title "Association between Mycobacterium avium complex lung disease and serum vitamin D status, antimicrobial peptide levels, and bone mineral density" @default.
- W2895547776 cites W1066618571 @default.
- W2895547776 cites W1504356861 @default.
- W2895547776 cites W1525208545 @default.
- W2895547776 cites W1532643142 @default.
- W2895547776 cites W1551028857 @default.
- W2895547776 cites W1579698247 @default.
- W2895547776 cites W1985492756 @default.
- W2895547776 cites W2000049370 @default.
- W2895547776 cites W2003293061 @default.
- W2895547776 cites W2004547921 @default.
- W2895547776 cites W2016368666 @default.
- W2895547776 cites W2026449016 @default.
- W2895547776 cites W2070800711 @default.
- W2895547776 cites W2074963908 @default.
- W2895547776 cites W2084954530 @default.
- W2895547776 cites W2104071542 @default.
- W2895547776 cites W2113926700 @default.
- W2895547776 cites W2119869365 @default.
- W2895547776 cites W2123708792 @default.
- W2895547776 cites W2124580054 @default.
- W2895547776 cites W2126984784 @default.
- W2895547776 cites W2129155846 @default.
- W2895547776 cites W2136984894 @default.
- W2895547776 cites W2142447693 @default.
- W2895547776 cites W2155638837 @default.
- W2895547776 cites W2165877084 @default.
- W2895547776 cites W2172055936 @default.
- W2895547776 cites W2335512024 @default.
- W2895547776 cites W2543191549 @default.
- W2895547776 cites W2552907436 @default.
- W2895547776 doi "https://doi.org/10.1097/md.0000000000012463" @default.
- W2895547776 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6160122" @default.
- W2895547776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30235737" @default.
- W2895547776 hasPublicationYear "2018" @default.
- W2895547776 type Work @default.
- W2895547776 sameAs 2895547776 @default.
- W2895547776 citedByCount "10" @default.
- W2895547776 countsByYear W28955477762019 @default.
- W2895547776 countsByYear W28955477762020 @default.
- W2895547776 countsByYear W28955477762021 @default.
- W2895547776 countsByYear W28955477762022 @default.
- W2895547776 countsByYear W28955477762023 @default.
- W2895547776 crossrefType "journal-article" @default.
- W2895547776 hasAuthorship W2895547776A5048538074 @default.
- W2895547776 hasAuthorship W2895547776A5050972585 @default.
- W2895547776 hasAuthorship W2895547776A5054170761 @default.
- W2895547776 hasAuthorship W2895547776A5062985377 @default.
- W2895547776 hasAuthorship W2895547776A5069366555 @default.
- W2895547776 hasAuthorship W2895547776A5084313756 @default.
- W2895547776 hasBestOaLocation W28955477761 @default.
- W2895547776 hasConcept C124490489 @default.
- W2895547776 hasConcept C126322002 @default.
- W2895547776 hasConcept C134018914 @default.
- W2895547776 hasConcept C156957248 @default.
- W2895547776 hasConcept C2776541429 @default.
- W2895547776 hasConcept C2776886416 @default.
- W2895547776 hasConcept C2777714996 @default.
- W2895547776 hasConcept C2779329777 @default.
- W2895547776 hasConcept C2780221984 @default.
- W2895547776 hasConcept C71924100 @default.
- W2895547776 hasConcept C90924648 @default.
- W2895547776 hasConceptScore W2895547776C124490489 @default.
- W2895547776 hasConceptScore W2895547776C126322002 @default.
- W2895547776 hasConceptScore W2895547776C134018914 @default.
- W2895547776 hasConceptScore W2895547776C156957248 @default.
- W2895547776 hasConceptScore W2895547776C2776541429 @default.
- W2895547776 hasConceptScore W2895547776C2776886416 @default.
- W2895547776 hasConceptScore W2895547776C2777714996 @default.
- W2895547776 hasConceptScore W2895547776C2779329777 @default.
- W2895547776 hasConceptScore W2895547776C2780221984 @default.
- W2895547776 hasConceptScore W2895547776C71924100 @default.
- W2895547776 hasConceptScore W2895547776C90924648 @default.
- W2895547776 hasIssue "38" @default.
- W2895547776 hasLocation W28955477761 @default.
- W2895547776 hasLocation W28955477762 @default.
- W2895547776 hasLocation W28955477763 @default.
- W2895547776 hasLocation W28955477764 @default.
- W2895547776 hasLocation W28955477765 @default.
- W2895547776 hasOpenAccess W2895547776 @default.
- W2895547776 hasPrimaryLocation W28955477761 @default.
- W2895547776 hasRelatedWork W1530295206 @default.
- W2895547776 hasRelatedWork W1972798482 @default.
- W2895547776 hasRelatedWork W2046809491 @default.
- W2895547776 hasRelatedWork W2057982124 @default.
- W2895547776 hasRelatedWork W2139984428 @default.
- W2895547776 hasRelatedWork W2359070681 @default.
- W2895547776 hasRelatedWork W2555847803 @default.