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- W2895550858 abstract "Background Biological samples require one or more pretreatment steps before analysis and detection by mass spectrometry. This chapter discusses the different sample preparation steps performed in laboratories analyzing drugs and proteins in the clinical and research setting and introduces high-throughput applications. Content The general techniques discussed are dilution, centrifugation, sonication, and homogenization. Separation techniques are filtration and ultrafiltration, dialysis and microdialysis, desalting, buffer exchange, enzymatic hydrolysis, and acid-base digestion. The precipitation technique discussed is protein precipitation. Enrichment techniques are evaporation, solvent exchange, and derivatization. Extraction techniques reviewed are liquid-liquid extraction, solid-supported liquid-liquid extraction, and solid-phase extraction (off-line and online sample processing). The chromatographic techniques discussed are column-switching (single and dual column modes) for turbulent flow chromatography, restricted access media, monolithic columns, and immunoaffinity extraction. The evolving techniques described are dried blood spots, capillary microsampling, and tissue imaging." @default.
- W2895550858 created "2018-10-12" @default.
- W2895550858 creator A5008288587 @default.
- W2895550858 date "2018-01-01" @default.
- W2895550858 modified "2023-09-26" @default.
- W2895550858 title "Sample Preparation for Mass Spectrometry Applications" @default.
- W2895550858 cites W1547703061 @default.
- W2895550858 cites W1555718400 @default.
- W2895550858 cites W1612649559 @default.
- W2895550858 cites W1964263474 @default.
- W2895550858 cites W1965056844 @default.
- W2895550858 cites W1966418839 @default.
- W2895550858 cites W1967028528 @default.
- W2895550858 cites W1971038805 @default.
- W2895550858 cites W1974247636 @default.
- W2895550858 cites W1974983216 @default.
- W2895550858 cites W1975046677 @default.
- W2895550858 cites W1976236605 @default.
- W2895550858 cites W1976776660 @default.
- W2895550858 cites W1978697681 @default.
- W2895550858 cites W1979681640 @default.
- W2895550858 cites W1980409192 @default.
- W2895550858 cites W1981348524 @default.
- W2895550858 cites W1981596358 @default.
- W2895550858 cites W1982218301 @default.
- W2895550858 cites W1982781645 @default.
- W2895550858 cites W1983858391 @default.
- W2895550858 cites W1983948902 @default.
- W2895550858 cites W1986631688 @default.
- W2895550858 cites W1987116001 @default.
- W2895550858 cites W1988665133 @default.
- W2895550858 cites W1989077917 @default.
- W2895550858 cites W1990252879 @default.
- W2895550858 cites W1991417422 @default.
- W2895550858 cites W1992407106 @default.
- W2895550858 cites W1992512309 @default.
- W2895550858 cites W1993429674 @default.
- W2895550858 cites W1996453460 @default.
- W2895550858 cites W1997958695 @default.
- W2895550858 cites W1998138438 @default.
- W2895550858 cites W1998379582 @default.
- W2895550858 cites W1999159081 @default.
- W2895550858 cites W1999205867 @default.
- W2895550858 cites W1999307269 @default.
- W2895550858 cites W1999812289 @default.
- W2895550858 cites W2000542203 @default.
- W2895550858 cites W2006883119 @default.
- W2895550858 cites W2007335128 @default.
- W2895550858 cites W2007621209 @default.
- W2895550858 cites W2009738094 @default.
- W2895550858 cites W2009872638 @default.
- W2895550858 cites W2010572837 @default.
- W2895550858 cites W2010779317 @default.
- W2895550858 cites W2010878697 @default.
- W2895550858 cites W2012714851 @default.
- W2895550858 cites W2013814029 @default.
- W2895550858 cites W2014910142 @default.
- W2895550858 cites W2016022113 @default.
- W2895550858 cites W2017719009 @default.
- W2895550858 cites W2018126606 @default.
- W2895550858 cites W2019346496 @default.
- W2895550858 cites W2020458605 @default.
- W2895550858 cites W2020964839 @default.
- W2895550858 cites W2021066675 @default.
- W2895550858 cites W2022862881 @default.
- W2895550858 cites W2030018352 @default.
- W2895550858 cites W2030031586 @default.
- W2895550858 cites W2033223023 @default.
- W2895550858 cites W2037446268 @default.
- W2895550858 cites W2037998272 @default.
- W2895550858 cites W2038965519 @default.
- W2895550858 cites W2039159829 @default.
- W2895550858 cites W2040308794 @default.
- W2895550858 cites W2040474006 @default.
- W2895550858 cites W2041415567 @default.
- W2895550858 cites W2041575674 @default.
- W2895550858 cites W2043259426 @default.
- W2895550858 cites W2045460764 @default.
- W2895550858 cites W2047642236 @default.
- W2895550858 cites W2048718351 @default.
- W2895550858 cites W2049606341 @default.
- W2895550858 cites W2051683517 @default.
- W2895550858 cites W2052179000 @default.
- W2895550858 cites W2052512642 @default.
- W2895550858 cites W2053426474 @default.
- W2895550858 cites W2054531311 @default.
- W2895550858 cites W2056353108 @default.
- W2895550858 cites W2056944801 @default.
- W2895550858 cites W2057210581 @default.
- W2895550858 cites W2057699619 @default.
- W2895550858 cites W2058746843 @default.
- W2895550858 cites W2059667451 @default.
- W2895550858 cites W2060121473 @default.
- W2895550858 cites W2060839656 @default.
- W2895550858 cites W2061776657 @default.
- W2895550858 cites W2064623724 @default.
- W2895550858 cites W2065024909 @default.
- W2895550858 cites W2066826426 @default.