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- W2895575422 abstract "Abstract We describe the case of a patient diagnosed with neurofibromatosis type 1 ( NF 1) where unusually extensive and multiple osteolytic lesions of both jaws consistent with central giant cell granulomas ( CGCG ) caused massive bone destruction and left her almost “jawless.” The patient was a 58‐year‐old woman who at the age of 15 years was diagnosed with NF 1 and at the age of 53 years underwent radiation therapy for nasal obstruction due to CGCG . The most significant intraoral findings were brown tumors on the maxillary gingiva; bilateral expansion of the hard palate; and a yellow mass on the floor of the mouth. Head and neck examination revealed mandibular asymmetry and features consistent with NF 1. Panoramic radiograph and cone beam computed tomography disclosed multiple radiolucent masses. Although the occurrence of multiple CGCG of the jaws in patients with NF 1 is rare, early diagnosis, regular follow‐up and proper therapeutic intervention may limit the extent of bone destruction." @default.
- W2895575422 created "2018-10-12" @default.
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- W2895575422 date "2018-10-05" @default.
- W2895575422 modified "2023-10-16" @default.
- W2895575422 title "Multiple osteolytic lesions of the jaws in a patient with neurofibromatosis type I. A case report and focused literature review" @default.
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- W2895575422 doi "https://doi.org/10.1111/ors.12389" @default.
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