FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895587284> ?p ?o ?g. }

• W2895587284 endingPage "3680" @default.
• W2895587284 startingPage "3671" @default.
• W2895587284 abstract "De novo sequencing offers an alternative to database search methods for peptide identification from mass spectra. Since it does not rely on a predetermined database of expected or potential sequences in the sample, de novo sequencing is particularly appropriate for samples lacking a well-defined or comprehensive reference database. However, the low accuracy of many de novo sequence predictions has prevented the widespread use of the variety of sequencing tools currently available. Here, we present a new open-source tool, Postnovo, that postprocesses de novo sequence predictions to find high-accuracy results. Postnovo uses a predictive model to rescore and rerank candidate sequences in a manner akin to database search postprocessing tools such as Percolator. Postnovo leverages the output from multiple de novo sequencing tools in its own analyses, producing many times the length of amino acid sequence information (including both full- and partial-length peptide sequences) at an equivalent false discovery rate (FDR) compared to any individual tool. We present a methodology to reliably screen the sequence predictions to a desired FDR given the Postnovo sequence score. We validate Postnovo with multiple data sets and demonstrate its ability to identify proteins that are missed by database search even in samples with paired reference databases." @default.
• W2895587284 created "2018-10-12" @default.
• W2895587284 creator A5008870583 @default.
• W2895587284 creator A5041810225 @default.
• W2895587284 creator A5055420845 @default.
• W2895587284 date "2018-10-02" @default.
• W2895587284 modified "2023-10-12" @default.
• W2895587284 title "Postnovo: Postprocessing Enables Accurate and FDR-Controlled de Novo Peptide Sequencing" @default.
• W2895587284 cites W1965403325 @default.
• W2895587284 cites W1973592885 @default.
• W2895587284 cites W1975224781 @default.
• W2895587284 cites W1977870579 @default.
• W2895587284 cites W1991502938 @default.
• W2895587284 cites W1998149006 @default.
• W2895587284 cites W2001848433 @default.
• W2895587284 cites W2002125267 @default.
• W2895587284 cites W2002452099 @default.
• W2895587284 cites W2016266997 @default.
• W2895587284 cites W2016916625 @default.
• W2895587284 cites W2026465178 @default.
• W2895587284 cites W2028673251 @default.
• W2895587284 cites W2030984826 @default.
• W2895587284 cites W2038615001 @default.
• W2895587284 cites W2039863924 @default.
• W2895587284 cites W2046191576 @default.
• W2895587284 cites W2046373836 @default.
• W2895587284 cites W2049671843 @default.
• W2895587284 cites W2053943711 @default.
• W2895587284 cites W2055043387 @default.
• W2895587284 cites W2063218600 @default.
• W2895587284 cites W2069773272 @default.
• W2895587284 cites W2070712932 @default.
• W2895587284 cites W2083911564 @default.
• W2895587284 cites W2090647436 @default.
• W2895587284 cites W2095650214 @default.
• W2895587284 cites W2096057003 @default.
• W2895587284 cites W2099530435 @default.
• W2895587284 cites W2101879802 @default.
• W2895587284 cites W2112078820 @default.
• W2895587284 cites W2139397135 @default.
• W2895587284 cites W2196225219 @default.
• W2895587284 cites W2232431226 @default.
• W2895587284 cites W2291680095 @default.
• W2895587284 cites W2407926091 @default.
• W2895587284 cites W2461971948 @default.
• W2895587284 cites W2464250025 @default.
• W2895587284 cites W2512489438 @default.
• W2895587284 cites W2513487313 @default.
• W2895587284 cites W2523787414 @default.
• W2895587284 cites W2526956161 @default.
• W2895587284 cites W2531537628 @default.
• W2895587284 cites W2534641525 @default.
• W2895587284 cites W2561019872 @default.
• W2895587284 cites W2566894387 @default.
• W2895587284 cites W2575647550 @default.
• W2895587284 cites W2591178039 @default.
• W2895587284 cites W2592973894 @default.
• W2895587284 cites W2603081759 @default.
• W2895587284 cites W2613852274 @default.
• W2895587284 cites W2671751787 @default.
• W2895587284 cites W2736540742 @default.
• W2895587284 cites W2736859409 @default.
• W2895587284 cites W2754963868 @default.
• W2895587284 cites W752259472 @default.
• W2895587284 doi "https://doi.org/10.1021/acs.jproteome.8b00278" @default.
• W2895587284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30277077" @default.
• W2895587284 hasPublicationYear "2018" @default.
• W2895587284 type Work @default.
• W2895587284 sameAs 2895587284 @default.
• W2895587284 citedByCount "9" @default.
• W2895587284 countsByYear W28955872842019 @default.
• W2895587284 countsByYear W28955872842020 @default.
• W2895587284 countsByYear W28955872842022 @default.
• W2895587284 countsByYear W28955872842023 @default.
• W2895587284 crossrefType "journal-article" @default.
• W2895587284 hasAuthorship W2895587284A5008870583 @default.
• W2895587284 hasAuthorship W2895587284A5041810225 @default.
• W2895587284 hasAuthorship W2895587284A5055420845 @default.
• W2895587284 hasConcept C104317684 @default.
• W2895587284 hasConcept C116834253 @default.
• W2895587284 hasConcept C124101348 @default.
• W2895587284 hasConcept C193244246 @default.
• W2895587284 hasConcept C23123220 @default.
• W2895587284 hasConcept C2778112365 @default.
• W2895587284 hasConcept C41008148 @default.
• W2895587284 hasConcept C41584329 @default.
• W2895587284 hasConcept C48000682 @default.
• W2895587284 hasConcept C54355233 @default.
• W2895587284 hasConcept C59822182 @default.
• W2895587284 hasConcept C70721500 @default.
• W2895587284 hasConcept C86803240 @default.
• W2895587284 hasConcept C97854310 @default.
• W2895587284 hasConceptScore W2895587284C104317684 @default.
• W2895587284 hasConceptScore W2895587284C116834253 @default.
• W2895587284 hasConceptScore W2895587284C124101348 @default.
• W2895587284 hasConceptScore W2895587284C193244246 @default.
• W2895587284 hasConceptScore W2895587284C23123220 @default.
• W2895587284 hasConceptScore W2895587284C2778112365 @default.

• next