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- W2895590295 abstract "Introduction: Indocyanine green fluorescence-guided surgery (ICG-FGS) has emerged as a potential new imaging modality for improving the detection of hepatic focal lesions in both, primary and metastatic liver tumors. We want demonstrate the technique and details for a complete and safe liver resection through using ICG-FGS surgery and to assess its potential applications. Methods: From December 2017 to 15 January 2018, 5 patients (1 primary, 4 metastatic tumors) underwent surgery with ICG-FGS. ICG (0.4 mg/kg) was injected intravenously 24 h before surgery. We perform hepatic IOUS, as usually, at every patient. Fluorescence was investigated prior to resection to detect liver lesions, during hepatic transection to guide surgery (with particular attention to assess surgical margins) and for pathological esamination. Results: All operations were successful and had a mean duration time of 224'(range 120-480). ICG- Fluorescence Imaging (ICG-FI) detected all already known lesions (n= 7) and identified 1 additional small tumor (1 metastasis, diagnostic improvement 12,5%). All metastatic nodules were hypofluorescent with a hyperfluorescent rim, whereas hepatocellular carcinoma was hyperfluorescent. In all cases, in vivo and ex vivo fluorescence revealed cleared liver margins, and postoperative pathological examination greatly benefited of liver fluorescence to assess radicality. Conclusions: ICG-FGS was shown to be an effective and safe instrument to help intraoperative staging and to assess radicality in the surgical treatment of primary and metastatic liver tumors." @default.
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- W2895590295 date "2018-09-01" @default.
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- W2895590295 title "Indocyanine green fluorescence guided surgery in primary and metastatic liver tumors: preliminary results from a single-center experience" @default.
- W2895590295 doi "https://doi.org/10.1016/j.hpb.2018.06.2987" @default.
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