Matches in SemOpenAlex for { <https://semopenalex.org/work/W2895591211> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2895591211 abstract "Trastuzumab is a monoclonal antibody effective in treating metastatic breast carcinomas. Cardiotoxicity is the most commonly reported adverse event occurring when used in combination with anthracycline derivatives. Even though pulmonary toxicities are uncommon, immediate withdrawal of the drug is recommended and only reinitiates after the vitals of the patient have become normal. Here, we discuss the case of an 81-year-old female patient who was treated with Injection Trastuzumab for the treatment of breast cancer with metastasis to lungs and received 6 cycles without any major complications. However, 24 h post the last dose; the patient developed a sudden onset of breathlessness and desaturation and was intubated in view of severe metabolic and respiratory acidosis. Blood investigations revealed elevated brain natriuretic peptide, aspartate transaminase, and alkaline phosphatase. Her blood and urine cultures were found to be sterile. She was managed with IV antibiotics, nebulizations, IV fluids, and other supportive medications and had improved considerably. However, on the 11th day, her condition had deteriorated and developed bradycardia. The patient could not be revived and died. Review of the patient’s medication did not reveal the presence of any other possible drugs capable of producing pulmonary toxicity. Trastuzumab should be avoided in patients with underlying respiratory or cardiac issues." @default.
- W2895591211 created "2018-10-12" @default.
- W2895591211 creator A5037993510 @default.
- W2895591211 creator A5058326187 @default.
- W2895591211 creator A5076220056 @default.
- W2895591211 date "2018-10-07" @default.
- W2895591211 modified "2023-09-24" @default.
- W2895591211 title "TRASTUZUMAB-INDUCED RESPIRATORY DISTRESS: A CASE REPORT" @default.
- W2895591211 doi "https://doi.org/10.22159/ajpcr.2018.v11i10.24343" @default.
- W2895591211 hasPublicationYear "2018" @default.
- W2895591211 type Work @default.
- W2895591211 sameAs 2895591211 @default.
- W2895591211 citedByCount "1" @default.
- W2895591211 countsByYear W28955912112018 @default.
- W2895591211 crossrefType "journal-article" @default.
- W2895591211 hasAuthorship W2895591211A5037993510 @default.
- W2895591211 hasAuthorship W2895591211A5058326187 @default.
- W2895591211 hasAuthorship W2895591211A5076220056 @default.
- W2895591211 hasBestOaLocation W28955912111 @default.
- W2895591211 hasConcept C121608353 @default.
- W2895591211 hasConcept C126322002 @default.
- W2895591211 hasConcept C141983124 @default.
- W2895591211 hasConcept C197934379 @default.
- W2895591211 hasConcept C2775930923 @default.
- W2895591211 hasConcept C2777495988 @default.
- W2895591211 hasConcept C2777953023 @default.
- W2895591211 hasConcept C2778233292 @default.
- W2895591211 hasConcept C2779786085 @default.
- W2895591211 hasConcept C29730261 @default.
- W2895591211 hasConcept C42219234 @default.
- W2895591211 hasConcept C530470458 @default.
- W2895591211 hasConcept C534529494 @default.
- W2895591211 hasConcept C71924100 @default.
- W2895591211 hasConcept C84393581 @default.
- W2895591211 hasConceptScore W2895591211C121608353 @default.
- W2895591211 hasConceptScore W2895591211C126322002 @default.
- W2895591211 hasConceptScore W2895591211C141983124 @default.
- W2895591211 hasConceptScore W2895591211C197934379 @default.
- W2895591211 hasConceptScore W2895591211C2775930923 @default.
- W2895591211 hasConceptScore W2895591211C2777495988 @default.
- W2895591211 hasConceptScore W2895591211C2777953023 @default.
- W2895591211 hasConceptScore W2895591211C2778233292 @default.
- W2895591211 hasConceptScore W2895591211C2779786085 @default.
- W2895591211 hasConceptScore W2895591211C29730261 @default.
- W2895591211 hasConceptScore W2895591211C42219234 @default.
- W2895591211 hasConceptScore W2895591211C530470458 @default.
- W2895591211 hasConceptScore W2895591211C534529494 @default.
- W2895591211 hasConceptScore W2895591211C71924100 @default.
- W2895591211 hasConceptScore W2895591211C84393581 @default.
- W2895591211 hasLocation W28955912111 @default.
- W2895591211 hasOpenAccess W2895591211 @default.
- W2895591211 hasPrimaryLocation W28955912111 @default.
- W2895591211 hasRelatedWork W2032820594 @default.
- W2895591211 hasRelatedWork W2034690275 @default.
- W2895591211 hasRelatedWork W2131513128 @default.
- W2895591211 hasRelatedWork W2147529602 @default.
- W2895591211 hasRelatedWork W2192030523 @default.
- W2895591211 hasRelatedWork W2895591211 @default.
- W2895591211 hasRelatedWork W2990994911 @default.
- W2895591211 hasRelatedWork W4210633330 @default.
- W2895591211 hasRelatedWork W4225390758 @default.
- W2895591211 hasRelatedWork W2134331647 @default.
- W2895591211 isParatext "false" @default.
- W2895591211 isRetracted "false" @default.
- W2895591211 magId "2895591211" @default.
- W2895591211 workType "article" @default.