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- W2895727527 abstract "Introduction: The choice of total pancreatectomy (TP) for the treatment of pancreatic lesions is conditioned by the postoperative morbidity, postoperative mortality and complications associated with this technique, such as diabetes mellitus, exocrine insufficiency and impaired quality of life (QOL) The current improvement of postoperative management is conditioning an increase in the indication of this surgery. Method: We present four patients with TP and discuss the indications. Results: A 79-years-old man with intraductal papillary mucinous neoplasia (IPMN) with main duct >1 cm and pancreatic atrophy. He was chosen for obstruction of main pancreatic duct. A 53-years-old woman with IPMN and recurrent pancreatitis. TP was performed due to multifocal IPMN. A 71-years-old woman with IPMN. She was chosen for the obstruction of Wirsung. A 73-years-old woman with pancreatic adenocarcinoma and portal infiltration. TP was performed due to risk of anastomotic leakage. Discussion: The mortality related to TP has decrease in the last time and the survival and quality of life associated with this technique is similar to cephalic duodenopancreatectomy. Indications of TP include both benign and malignant pancreatic diseases. This technique may be indicated preoperatively due to multifocal tumors or pancreatic obstruction, or intraoperatively due to soft pancreatic remainder or risk of anastomotic leakage. Conclusion: TP is a treatment option in selected patients with low morbi-mortality and good results in QOL. The decision to perform a TP is a challenge for the patient and the surgeon and must be carried out with caution." @default.
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- W2895727527 date "2018-09-01" @default.
- W2895727527 modified "2023-10-14" @default.
- W2895727527 title "When to consider total pancreatectomy?" @default.
- W2895727527 doi "https://doi.org/10.1016/j.hpb.2018.06.2361" @default.
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