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- W2895743478 abstract "Background The need for dose adjustment in patients with renal impairment is well known. Despite globally implemented interventions for improvement in dose adjustment, there is dazing noncompliance to dosing recommendations in renal impairment, which came into focus in the 21 st century. Purpose To determine the degree of drug dose adjustment in hospitalised patients with renal impairment, frequency and type of drugs that need to be adjusted with regard to creatinine clearance (CrCl). To assess the acceptance rate of the clinical pharmacist interventions addressed to doctors. Material and methods Prospective interventional study was conducted at the Department of Internal Medicine during a 3 month period. Using the Cockroft–Gault equation, patients with renal impairment were identified at admission and their pharmacotherapy were reviewed daily. Prescribed drugs which required dose adjustment in renal impairment were classified as adjusted or unadjusted. For the latter, written pharmaceutical intervention was sent to the concerned doctor. Results Almost one-third of all admitted patients had CrCl Conclusion Nearly every third admitted patient had impaired renal function. Frequent dose unadjustments increase the risk of adverse drug reactions. Clinical pharmacists can increase the rate of proper dose adjustments in patients with renal impairment. The implementation of systemically provided pharmaceutical care in hospital wards can facilitate positive treatment outcomes and increase patient safety. References and/or Acknowledgements Many thanks to Professor Vesna Bacic Vrca No conflict of interest" @default.
- W2895743478 created "2018-10-12" @default.
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- W2895743478 date "2018-03-01" @default.
- W2895743478 modified "2023-09-24" @default.
- W2895743478 title "4CPS-220 Clinical pharmacist interventions in hospitalised patients with renal impairment" @default.
- W2895743478 doi "https://doi.org/10.1136/ejhpharm-2018-eahpconf.310" @default.
- W2895743478 hasPublicationYear "2018" @default.
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