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• W2895743625 startingPage "6449" @default.
• W2895743625 abstract "A novel multicomponent reaction of p-(trifluoromethyl)-p-quinolsilyl ethers, ketones, and nitriles was developed for the efficient synthesis of p-trifluoromethylated N-benzylamides. The key step of the reaction involves the formation of an unstable condensation precursor in situ generated form the condensation of p-(trifluoromethyl)-p-quinolsilyl ethers with ketones. This work provides a significant expansion to the Ritter-type reaction, and the reaction can proceed under mild reaction conditions and tolerate various nitriles including both aryl and aliphatic nitriles." @default.
• W2895743625 created "2018-10-12" @default.
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• W2895743625 date "2018-10-05" @default.
• W2895743625 modified "2023-10-15" @default.
• W2895743625 title "A Ritter-Type Route to <i>N</i>-Benzylamides by Multicomponent Reaction Based on <i>p</i>-(Trifluoromethyl)-<i>p</i>-quinols" @default.
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• W2895743625 doi "https://doi.org/10.1021/acs.orglett.8b02762" @default.
• W2895743625 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30289266" @default.
• W2895743625 hasPublicationYear "2018" @default.
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