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- W2895791058 abstract "Abstract As a prototype of a single‐cell detecting technique, a single silicon nanowire‐based (SiNW‐based) fluorescent sensor for endogenous hypochlorite in a macrophage is constructed. The fluorescent sensor for hypochlorite is prepared by decorating a near‐infrared dye, IR780 onto the surface of SiNWs. The sensor exhibits high sensitivity and linear dependence of the fluorescence intensities on the hypochlorite concentrations. With the help of micromanipulation and laser scanning confocal microscopy, detection of endogenous hypochlorite in a single macrophage is realized by penetrating the single SiNW‐based sensor into individual cells. The current SiNW‐based sensor will possess potential value in revealing the role of hypochlorite in physiology and pathology. Such single‐cell detecting techniques can be expanded to other fields. This work will open a new door to a variety of novel studies by combining the strengths of single‐cell detecting techniques with biology." @default.
- W2895791058 created "2018-10-26" @default.
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- W2895791058 date "2018-10-09" @default.
- W2895791058 modified "2023-10-14" @default.
- W2895791058 title "Single Silicon Nanowire‐Based Fluorescent Sensor for Endogenous Hypochlorite in an Individual Cell" @default.
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- W2895791058 doi "https://doi.org/10.1002/adbi.201800213" @default.
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